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The immune system is integral to cardiovascular health and disease. Targeting inflammation ameliorates adverse cardiovascular outcomes. Atherosclerosis, a major underlying cause of cardiovascular disease, is conceptualized as lipid-driven inflammation in which macrophages play a nonredundant role. However, evidence emerging so far from single-cell atlases suggests a dichotomy between lipid-associa

The art of living and the art of eating: Professor Linnaeus recommends. By Gunnar Broberg. As professor of medicine, Linnaeus taught dietetics. He followed the pattern outlined by Galen and Regimen salernitatis, adding an extensive material originating from general cultural history and his own experience.Early in his life he wrote Diaeta naturalis, a collection of rules focusing the blessings of n

Regular exercise leads to widespread salutary effects, and there is increasing recognition that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited data exist regarding the plasma proteomic changes that occur in response to regular exercise. Here, we perform large-scale plasma proteomic profiling in 654 healthy human study participants before and after a supe

Despite their detrimental circumstances, the number of refugee-owned businesses is on the rise—a situation referred to as “the paradox of refugee entrepreneurship.” However, a key question is how refugees, having undergone extreme life disruption due to war, conflict, and forced displacement, fare as entrepreneurs in their host country. Extant studies do not address this question, as they primaril

Short-chain fatty acids (SCFA) are involved in immune system and inflammatory responses. We comprehensively assessed the host genetic and gut microbial contribution to a panel of eight serum and stool SCFAs in two cohorts (TwinsUK, n = 2507; ZOE PREDICT-1, n = 328), examined their postprandial changes and explored their links with chronic and acute inflammatory responses in healthy individuals and

Research centers represent a specific organizational format for linking the traditional university organization with external actors, goals, and processes in time-limited, concentrated efforts of research and collaboration. Yet, the center format contains large variations, and centers act as interfaces between university organizations, societal actors, and research funders in multifaceted ways. In

As a dominant representative of biobased construction materials, an increased use of timber bears potential to contribute to climate change mitigation. This work investigated public attitudes towards timber as a building material, particularly focussing on the perception of fire safety properties and associated risks. In past studies timber’s susceptibility to fire was often acknowledged by stakeh

With the world facing severe ecological degradation, we hear calls for radical change more and more often. One of these calls is for degrowth in materially wealthy nations, including the Nordics. Degrowth fundamentally challenges the modern assumption that economic growth is good for humanity and the planet, and therefore necessitates change in civil society, state and production. In the contempor

The chapter discusses the importance of the EU continuing to promote improved living and working conditions for its citizens without simultaneously risking competition between workers from different member states. The problem discussion is based on the significance of social improvements for the EU to maintain support among citizens and the challenges that arise when EU law encounters the differen

Background: Summary statistics often hide individual patients' suffering, thereby impeding quality improvement efforts. Objectives: We aimed to show the experience of a population with health care toward the end of life while preserving the experience of the individual. Design: We developed a data display method called per-patient illness trajectory analysis. We tested it using a demonstration coh