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Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease caused by both genetic and environmental factors. Genome scans in families with SLE point to multiple potential chromosomal regions that harbor SLE susceptibility genes, and association studies in different populations have suggested several susceptibility alleles for SLE. Increased production of type I interferon (IFN) an

Perceived participation in life situations in persons with late effects of polio

Objective: To investigate how persons with late effects of polio perceive their participation and problems with participation in life situations and to determine the association between perceived problems with participation and sex, age, marital status, use of mobility aids and access to instrumental support. Design: Cross-sectional. Subjects: A total of 160 persons with prior polio 6-30 months af

Productivity, vitality and utility in a group of healthy professionally active individuals with nocturia

OBJECTIVES To assess the effect of nocturia on productivity, vitality and utility in a selected group of professionally active individuals with nocturia, compared with matched controls, and investigate the effect of symptom severity, to test the hypothesis that lack of sleep caused by frequent sleep interruptions could reduce an individuals' daytime energy and activity levels. SUBJECTS AND METHODS

Participation in Green Consumer Policies: Deliberative Democracy under the Wrong Conditions?

In policy debates about reducing environmental and social harms, political consumerism is often called for by actors from a broad political spectrum. This paper examines traits of deliberative democracy in cases where instruments of political consumerism (eco-labelling, certificates and standards) are developed. The empirical cases are processes surrounding eco-labelled, standardised forestry, foo

Non-invasive, label-free cell counting and quantitative analysis of adherent cells using digital holography

Manual cell counting is time consuming and requires a high degree of skill on behalf of the person performing the count. Here we use a technique that utilizes digital holography, allowing label-free and completely non-invasive cell counting directly in cell culture vessels with adherent viable cells. The images produced can provide both quantitative and qualitative phase information from a single

Cellulase production based on hemicellulose hydrolysate from steam-pretreated willow

The production cost of cellulolytic enzymes is a major contributor to the high cost of ethanol production from lignocellulosics using enzymatic hydrolysis. The aim of the present study was to investigate the cellulolytic enzyme production of Trichoderma reesei Rut C 30, which is known as a good cellulase secreting micro-organism, using willow as the carbon source. The willow, which is a fast-growi

Twins studies as a model for studies on the interaction between smoking and genetic factors in the development of chronic bronchitis

Smoking is the main risk factor for COPD (chronic obstructive pulmonary disease) but genetic factors are of importance, since only a subset of smokers develops the disease. Sex differences have been suggested both in disease prevalence and response to environmental exposures. Furthermore, it has been shown that acquisition of 'addiction' to smoking is partly genetically mediated. Disease cases and

Activity concentrations of radionuclides in energy production from peat, wood chips and straw

In this thesis quantitative analyses of radionuclide concentrations in bioenergy fuels such as peat, wood chips and straw are presented. For comparison a brief description is included of radionuclide concentrations and radiation doses from other sources of power and also from some industrial applications. Radiation is a natural phenomenon and radionuclides occur naturally. The first man-made spre

An observation study of the level at which parents participate in decisions during their child’s hospitalisation

Abstract When a child is hospitalized, the parents find themselves in an unfamiliar environment and their parental role changes. They are in a stressful and often anxiety-filled situation and it may be difficult for them to participate in decisions. The purpose of this study was to examine the extent to which parents participate in decisions during the course of events when their child is hospital

The Surprise of Candour: Employee Cynicism and technological Change in Late Modernity Work

As an attitude characterized by frustration, hopelessness, betrayal and disillusionment (Andersson, 1996; Wanous et al. 1994) employee cynicism or organizational cynicism could be considered a specific attitude of interest to the research of information system (IS) implementations. Today a broad literature body has emerged within the IS research community investigating the organizational consequen

Professional Digital Encyclopaedias as Socio-Technical Systems

This paper presents on-going research on the production of knowledge in contemporary professional digital encyclopaedias. By adopting a theoretical perspective that considers the interplay of humans, non-humans and practices at the same level, it develops further a socio-technical perspective on knowledge production. Methodologically, the project involves an ethnographic study staring from two edi

Predictive text entry using syntax and semantics

Most cellular telephones use numeric keypads, where texting is supported by dictionaries and frequency models. Given a key sequence, the entry system recognizes the matching words and proposes a rank-ordered list of candidates. The ranking quality is instrumental to an effective entry. This paper describes a new method to enhance entry that combines syntax and language models. We first investigat

Investigation of the Effects of Leaching on the Scaling Resistance of Concrete

Damage to the concrete surface can be observed at the waterline of hydraulic structures in fresh water bodies in cold climates. Gradual deterioration of the concrete surface leads to exposure of coarse aggregate. Superficial damage at the waterline is commonly assumed to be caused by drifting ice floes. However, deterioration of concrete at the waterline may also involve leaching and frost action.