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The activities of cluster initiatives operating as systemic intermediaries and supporting networking activities have been discussed in prior studies. We integrate insights from the cluster theory and the literature on sustainability transitions to study the activities of clusters acting as systemic intermediaries in the different phases of the development of a forest-based bioeconomy, namely (1) p

Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored. Abnormal biliverdin reductase-A (BVR-A) levels were observed in both T2D and AD and were associated with insulin resistance. Here, we demonstrate that re

Intra-islet crosstalk has become a focus area to fully understand the regulation of insulin secretion and impaired β-cell function in type 2 diabetes (T2D). Here, we put forward evidence for insulin-like growth factor binding protein 7 (IGFBP7) as a potential protein involved in autocrine and paracrine β-cell regulation. We showed presence of IGFBP7 in granules of both human α- and β-cells and mea

Qatar 2022 has become a symbol of sportswashing, a flagpost for discussions about accountability, responsibility, and morality within different sport disciplines, football being a prime example. “Moral violation” has been listed as the crime surrounding sportswashing (Fruh, Archer & Wojtowicz 2023, 103). After frenzied use of the word in connection to the last football world cup 2022, there ca

Diplomatihistorien hör till en av historievetenskapens giganter som under sin livsbana ofta ifrågasatts och utmanats. Denna artikel inleds med en historiografisk tillbakablick på framväxten av New Diplomatic History, dess definitioner av tidigmodern diplomati, samt en överblick av aktuella forskningsteman och frågor i internationell forskning. Särskilt fokus läggs på nordisk diplomatihistoria via Diplomatic history is one of the giants of historical scholarship, which has often been questioned and challenged throughout its lifetime. This article discusses the field of New Diplomatic History centered on definitions of diplomacy in general and specifically on research on the early modern period during the last decades. Special focus is placed on Nordic early modern diplomatic history through

Involving older people through co-design has become increasingly attractive as an approach to develop technologies for them. However, less attention has been paid to the internal dynamics and localized socio-material arrangements that enact this method in practice. In this paper, we show how the outcomes that can be achieved with user involvement often pertain to learning, but their content can di

Cells have an incredible ability to physically interact with neighboring cells and their environment. They can detect and respond to mechanical forces by converting mechanical stimuli into biochemical signals in a process known as mechanotransduction. This is a key process for the adaption of vascular smooth muscle and endothelial cells to altered flow and pressure conditions. Mechanical stimuli,

The division between rural and urban values and practices is a classic theme in disciplines such as European ethnology. During the last decades, the urban/rural divide seem to be renegotiated. Traditional, small scale agriculture and food production encapsulates values on display at many dinner tables of the upper middle urban class. This has lead to new business opportunities for rural actors, of

In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+) In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+)

The present article explores the implication of fairness as a regulatory and competition law concept applied to digital and Artificial Intelligence markets, in light of recent law and policy developments targeting the interaction between data, market power and competition law. Much of the policy discussions, legislative proposals as well some emerging case law elevate the matter of “fairness” in tThe present article explores the implication of fairness as a regulatory and competition law concept applied to digital and Artificial Intelligence markets, in light of recent law and policy developments targeting the interaction between data, market power and competition law.Much of the policy discussions, legislative proposals as well some emerging case law elevate the matter of “fairness” in th

This paper introduces a new framework – RoadRAT - to calculate the probability of inundation, wave runup, and storm erosion impacting coastal roads. Extreme value analysis is applied to annual maxima of observed and simulated still water level levels (SWL), total water levels (SWL + runup), and storm erosion volumes. The probability of impact on the road is derived both for the present conditions

Positive Energy Districts (PEDs) have rapidly emerged as a dominant policy instrument in Europe to accelerate urban climate transitions. PEDs target the district scale to optimise energy system performance through a combination of technical and social interventions. These activities are driven by an engineering logic that considers energy infrastructures to be rational, integrated, and governable.

Public libraries are increasingly acknowledged as important social infrastructures that can stimulate a sense of community, social cohesion and mental wellbeing. This paper investigates how (inter)national, provincial and local policies conceptualise and fund libraries as social infrastructures in three European cities. Drawing on 32 semi-structured interviews with library management and associatiPublic libraries are increasingly acknowledged as important social infrastructures that can stimulate a sense of community, social cohesion and mental wellbeing. This paper investigates how (inter)national, provincial and local policies conceptualise and fund libraries as social infrastructures in three European cities. Drawing on 32 semi-structured interviews with library management and associati

This cross-over experimental study aimed to examine the effects of filled chocolate consumption on blood glucose, insulin and ghrelin levels in 20 volunteers. After a one-week run-in period, study participants consumed two chocolate-based products, the tested biscuit or water for 21 days as a morning snack. After a two-week wash-out period, participants consumed another tested food for another 21