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Following decades of international collaboration to restore the Baltic Sea, we provide an assessment of the domestic implementation of measures agreed to limit diffuse agricultural pollution and the patterns of policy instruments applied. Despite the Helsinki Convention being unusually specific in detailing what measures countries should introduce, we find many shortcomings. These are most pronoun

Dipeptidyl peptidase-4 (DPP-4) inhibition is a glucose-lowering medication for type 2 diabetes. It works through stimulation of insulin secretion and inhibition of glucagon secretion in a glucose-dependent manner, resulting in lowered fasting and postprandial glycemia with low risk of hypoglycemia. As impaired insulin secretion and augmented glucagon secretion are key factors underlying hyperglyce

The majority of studies on internal brand equity examine its various dimensions and relationships between them. While prior research specifies organizational practices relevant for successful internal branding, the insights about the impact of essential organizational factors on internal brand equity are still limited. This study focuses on organizational resilience that is vital for the existenceThe majority of studies on internal brand equity examine its various dimensions and relationships between them. While prior research specifes organizational practices relevant for successful internal branding, the insights about the impact of essential organizational factors on internal brand equity are still limited. This study focuses on organizational resilience that is vital for the existence

Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and function and constitute risk factors for cognitive impairment. Alterations to taurine homeostasis can impact a number of biological processes, such as osmolarity control, calcium homeostasis, and inhibitory neurotransmission, and have been reported in both metabolic and neurodegenerative disorders. Models of n

TRPV2 is a ligand-operated temperature sensor with poorly defined pharmacology. Here, we combine calcium imaging and patch-clamp electrophysiology with cryo-electron microscopy (cryo-EM) to explore how TRPV2 activity is modulated by the phytocannabinoid Δ9-tetrahydrocannabiorcol (C16) and by probenecid. C16 and probenecid act in concert to stimulate TRPV2 responses including histamine release from

This interview-based study seeks to gain insight into the varying motivations behind car usage across different societal groups, alongside their attitudes towards travel behavior and transportation options. Its overarching goal is to delve deeper into the factors and constraints that influences individuals’ car use and mode choice. The research methodology involves collecting one-month travel data

Background In this study we examine whether the association between internet use and drinking could be different for different types of internet activities among adolescents. We also adjust for a number of theoretically relevant factors such as peer influence, unstructured activities, impulsivity and parental monitoring. Method The data are drawn from four cross-sectional surveys from the years 20

Economic crimes are – often – abstract crimes. Even for a somewhat well-trained accounting expert, these crimes are ambiguous, hard to detect and difficult to interpret. The abstract character of economic crimes is a problem in need of a solution. The abstractness needs to be reduced in order to make the court case judicially manageable, i.e. possible to work with during the process of trial and l

Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a

Research on early postwar documentation efforts related to the Second World War and the Holocaust conducted by survivors of Nazi persecution has expanded over the past two decades. Yet, research on how knowledge circulatedtween these efforts – especially across various “borders” – is still nascent. This chapter seeks to gain a better understanding of the role of women’s informalworks during the ea

We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) study. Fasting maternal insulin at 18-20gw was associated with abdominal/total fat mass ratio in newborns inde

Thirty years on, gender mainstreaming is still a dominant strategy for working with gender equality, even though its effectiveness is debated. This is also the case in Sweden. This study focuses on how organisations in public administration, particularly municipalities and regions, are introduced to and approach gender mainstreaming. It aims to contribute with in-depth knowledge of how organisatio