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The islets of Langerhans harbor multiple endocrine cell types that continuously respond to circulating nutrient levels in order to adjust their secretion of catabolic and anabolic hormones. Stimulus–secretion coupling in these cells is largely of metabolic nature; that is, metabolism of nutrient fuels yields signals that trigger and amplify secretion of hormones. Hence, metabolism in this micro-or
This chapter identifies factors impacting artists’ and cultural workers’ mental health. Structural conditions constitute power imbalances, such as inclusion mechanisms that influence privilege and possibilities to exhibit/publish artwork. Structural conditions also have an impact on the distribution of financial resources and the forming of new collective and inclusive networks, creating alternati
The construction industry is ranked number one compared to other sectors when it comes to waste generated in the European Union. Reuse of products is a priority within the European Union to reduce the need for virgin materials and to reduce waste. Looking back at past practices, various approaches have been suggested to increase reuse of construction products, although these approaches have fallen
I Sverige erbjuds förebyggande stödgrupper av socialtjänsten för barn som växer upp i familjer där det förekommer våld, missbruk eller psykisk ohälsa. Stigma som är kopplad till föräldrars problem och till socialtjänstens inblandning utgör hinder för barns deltagande i stödgrupper. I denna artikel undersöks barns och föräldrars upplevda motiv, hinder och fördelar med deltagandet genom att utforska
Abstract:Background Type 1 diabetes (T1D) is one of the most common childhood autoimmune diseases, with rising incidence worldwide with a male predominance. The etiology behind the disease is mostly unknown and it is essential to understand the factors that impact its development to prevent the disease and personalize the treatment. This thesis aims to examine sex-specific differences in T1D, expl
Music therapy is a “vocally demanding profession” [1, p. 46]. Currently, little is known about the prevalence and about the possible risk factors for voice disorders within music therapy. As music therapy workspaces may not always be ideal in terms of acoustics, the aim of the study is to investigate room acoustics and noise as risk factors for possible voice disorders among music therapists in Fi
Upon preschool enrollment, the child-teacher relationship becomes important for the child’s continued development. We suggest that parents may be essential in supporting the establishment of such relationships from the first weeks of the child’s preschool enrollment, the so-called “introduction process”. Recent data indicates that Nordic preschools organize this aspect of preschool introduction di
During the last few years Europe has made enormous progress towards free electron laser (FEL)-based research infrastructures. The FLASH facility [1] at DESY in Hamburg, Germany, has been in user operation since the summer of 2005; FERMI@Elettra [2] in Trieste, Italy, is under construction; the European XFEL [3] in Hamburg will start construction in summer 2008; and several other FEL projects are b
The world is becoming more and more data driven. There are many ways to collect, analyse and disseminate data, and data ecosystems are among the most important environments that we have for facilitating this. Spatial data is one of the data types in data ecosystems, and data ecosystems play a key role in further value creation of the spatial data created, maintained and shared in the SDI. The work
Obesity is a complex and chronic disease affecting hundreds of millions of people worldwide and has reached epidemic proportions. It is important to understand the underlying mechanisms to tackle this devastating disease, thus preventing its comorbidities. The epigenome, including DNA methylation and histone modifications, appears to be the link between genetics and nongenetic factors, modulating
Background: Pragmatics is the functional use of language in ever-changing social contexts. One early pragmatic ability is decontextualized language;to talk about events and things beyond here and now. Pragmatic difficulties are practically universal in ASD, but we don’t know about impairmentsin early pragmatic development. Further, the roles of early socio-communication and linguistic abilities in
Recent scholarly attention has focused on YouTubers' advertising practices and their influence on young followers' understanding of commercial content. Although previous studies primarily explore children's advertising literacy, they often treat YouTubers' influencer marketing as a unified phenomenon. This article distinguishes between two types of advertising: sponsored content and merchandise (m
BACKGROUND AND OBJECTIVES: Dementia cases are expected to triple during the next 30 years, highlighting the importance of finding modifiable risk factors for dementia. The aim of this study is to investigate whether adherence to conventional dietary recommendations or to a modified Mediterranean diet are associated with subsequent lower risk of developing all-cause dementia, Alzheimer's disease (A
Recent socioeconomic changes have created and intensified paradoxical organizational tensions that companies in numerous industries, including the construction sector, need to address when organizing and managing their activities. The nature of these tensions has not been sufficiently explored in the existing construction management literature. Thus, this study analyzes tensions between control an
Temporariness of refugee protection has started to emerge as a new standard in the policies of European countries. Given this development, the article focuses on one specific issue related to this temporariness: how refugee status intertwines with the conditions for the granting, revocation and prolongation of national residence permits. What are the interconnections between refugee status, includ
