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The rationale was to longitudinally follow-up interviews performed with heart recipients at their one-year examination in order to deepen the understanding of the meaning of surviving a heart transplant. The aim was to explore the meaning of surviving three years after a heart transplant compared to one year and to identify what constitutes the change process. A phenomenological–hermeneutic method
Food additives such as emulsifiers are used in increasing quantities in the food industry. The aim of this study was to compare three different emulsifiers (polysorbate 80 (P80), carboxymethyl cellulose (CMC), and β-lactoglobulin (β-lac) with regards to their effect on the stimulation of immune cells and intestinal permeability. The immune stimulatory effects were studied in the myeloid cell line
The curiosity of how the built environment, implicitly and explicitly, affects how citizens and users make choices in their everyday life related to climate change is on the rise. If there is a nicely designed bike lane, the choice to bike to work is much more easily taken than if the only option is a densely trafficked road. But which responsibility does the built environment have for citizens to
The present dissertation concerns how brain tissue properties reflect proficiency in two aspects of language use: the ability to use tonal cues on word stems to predict how words will end and the aptitude for learning foreign languages. While it is known that people differ in their language abilities and that damage to brain tissue cause loss of cognitive functions, it is largely unknown if differ
Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 genomic regions at a false dicovery rate (FDR) < 0.05 threshold and prioritize genes at 31, with five highli
The benefits of related variety on regional employment growth have become a prevailing view. However, these remain potential benefits unless channels (e.g. labour flows, inter-firm cooperation) and regional capabilities are in place to convert them into actual growth. This paper focuses on the labour mobility channel and proposes a way to measure the realized part of related variety. It demonstrat
District heating and cooling systems have been undergoing continuous development and have now reached the fifth-generation. In this innovative technology, connected buildings share local excess energy that otherwise would be wasted, which consequently reduces primary energy demands and carbon emissions. To date, the issue of implementing fifth-generation district systems on existing buildings has
Forced migration has dramatically increased around the world during the last decade. Integration, including health and work among migrants, is an important topic in many European countries; thus, it is crucial to develop relevant approaches to address challenges that arise in tandem with migration and work. Nature-based intervention is one such approach that addresses different kinds of challenges
What happens to dominant narratives and settled self-images of so-called peace nations when experiencing actual combat in out-of-area military missions? This question arises when studying the contemporary international engagement of small states that previously have mostly been engaged in peacekeeping with limited mandates and non-use of force restrictions. As today's international missions have a
Cancer is a highly heterogeneous disease caused by dysregulation in different cell types and tissues. However, different cancers may share common mechanisms. It is critical to identify decisive genes involved in the development and progression of cancer, and joint analysis of multiple cancers may help to discover overlapping mechanisms among different cancers. In this study, we proposed a fusion f
Fluctuations of neuronal activities in the brain may underlie relatively slow components of neurofunctional alterations, which can be modulated by food intake and related systemic metabolic statuses. Glutamatergic neurotransmission plays a major role in the regulation of excitatory tones in the central nervous system, although just how dietary elements contribute to the tuning of this system remai
This anthology explores the memory work performed by Baltic and Central and East European far-right actors in the online space. Situated at the crossroads between memory studies, far-right studies, and media studies, the volume’s seven chapters show how a wide range of far-right actors, from small movements to major parties, have exploited digital communication technologies in order to establish t
Previous research showed that living closer to bus stops could be a factor in promoting a healthy and active lifestyle. However, most of the studies relied on self-reported measures of distance, which might be affected by several confounders. In this study, self-reported distances among study participants were compared to actual ones, computed by the use of GIS (Geographic Information System) tech
Policies for shifting household electricity load are in focus in several countries, aimed at optimizing grid operation and tackling current and expected challenges from consumption patterns, like increased peak loads on the grid. Central here are recent developments in capacity charges, where the use of significant amounts of grid capacity is priced high, compared to the traditional pricing of ele
One of the hallmarks of type 1 but also type 2 diabetes is pancreatic islet inflammation, associated with altered pancreatic islet function and structure, if unresolved. IL-1β is a proinflammatory cytokine which detrimentally affects β-cell function. In the course of diabetes, complement components, including the central complement protein C3, are deregulated. Previously, we reported high C3 expre
