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Coeliac disease and type 1 diabetes are the most common paediatric autoimmune disorders. Both conditions have increasing incidence and can often coexist in a patient. The diseases share many genetic and immunological features, but diagnostic and treatment approaches vary substantially worldwide. Because of the often subtle presentation of coeliac disease in children with type 1 diabetes, many are

In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood pressure SNPs and 53 rare variants in genome-wide association studies of systolic, diastolic and pulse pressure in up to 776,078 participants from the Million Veteran Program

Dysregulation of autophagy has been observed in obesity and type 2 diabetes. Salt-inducible kinase 2 (SIK2), a member of the AMPK-related kinase family, is downregulated in adipocytes from obese or insulin resistant individuals and was previously demonstrated to regulate autophagy in cancer and normal cell lines. The aim of this study was thus to investigate a potential role of SIK2 in the regulat

Characterizing system performance under disruption is a growing area of research, particularly for describing a system's resilience to disruptive events. Within the framework of system resilience, this study approaches the minimization of a multiple-commodity system's vulnerability to multiple disruptions. The vulnerability of a system is defined by the degree to which commodities can no longer fl

This study is concerned with how impact from research and innovation (R&I) programmes is accounted for in impact evaluation reports. Establishing causal links between a research funding instrument and different effects, poses well known methodological difficulties. In the light of such challenges, textual accounts about causal links ought to be carefully written. Nevertheless, impact evaluatio

Family contributes to immigrant entrepreneurs’ business development in different ways. Family provides financial resources, accept lower salaries and offer volunteer based work. However, there is a lack of research investigating the role of family in the oppoertunity creation process.Thereby the aim of this paper is to explore how family influences the process of entrepreneurial opportunity create

Among the many unique flight behaviours of Common Swifts Apus apus, the most puzzling may be their ascents to high altitudes during both dusk and dawn. Twilight ascents have been hypothesized to be functionally related to information acquisition, including integration of celestial orientation cues, high-altitude visual landmarks and sampling of weather conditions. However, their exact purpose rema

White Paper For reprint orders, please contact: reprints@futuremedicine.com Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform Glyn N Stacey*,1, Peter W Andrews2, Ivana Barbaric2, Charlotta Boiers3,4, Amit Chandra5, Giulio Cossu6, Lynn Csontos7, Thomas JR Frith2, Jason A Halliwell2, Zoe Hewitt2, Mark McCall8, Harry D Moore2, M

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_regen_med.pdf - 2026-05-05