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Management of asymptomatic carotid disease continues to challenge medical practice and present evidence is often conflicting. Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis. Randomized trials provided support for Guidelines and Recommendations to intervene on asymptomatic stenosis, but at a known cost of
Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased organ donors aged 1–81 years. The transcriptomes of the extracted islets were analysed using Ion AmpliSeq sequencing. 346 genes that co-vary signific
The aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi’s What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomob
Over the last two decades, electrification has gained importance as a means to decarbonise the transport sector. As the number of Electric Vehicles (EVs) increases, it is important to consider broader system aspects as well, especially when deciding the type, coverage, size and location of the charging infrastructure required. This article proposes a new approach using agent-based simulations to a
This study assessed whether methods for capturing the pedestrian experience of outdoor lighting, previously evaluated in a full‐scale laboratory, were applicable in a real‐world setting. It applied an approach capturing the human response to outdoor lighting in a systematic way, by assessing perception, evaluation and behaviour in the lit environment. The study involved 81 participants from two ag
Omräkning av barns (≥2 år) kreatininvärden till motsvarande värden vid 18 års ålder och applicerade i Lund–Malmö-formeln för vuxna ledde till avsevärt förbättrad skattning av GFR bland barn vid uppmätt GFR <75, bibehållen noggrannhet ≥75 ml/min/1,73m2 och likvärdig med pediatriska formler.Lund–Malmö-formeln kan användas under hela livet ≥2 år utan plötsliga artificiella förändringar i skattad GFR
Preventive home visits (PHVs) are offered to older persons with the purpose of promoting health and preventing risks on an individual level. However, aspects of health need to be considered on a societal level as well. This study aims to get a deeper understanding of perceptions of the usability of the information compiled during the PHVs to promote health, among older persons, on a societal level
C-terminal α-amidation is the final and essential step in the biosynthesis of several peptide hormones. Peptidylglycine α-amidating monooxygenase (PAM) is the only known enzyme to catalyse this reaction. PAM amidating activity (AMA) is known to be present in human circulation, but its physiological role and significance as a clinical biomarker remains unclear. We developed a PAM-specific amidation
Barnamordsbrottet ansågs under 1600-talet i Sverige vara den mest samhällsfarliga handling som kunde begås och gav lagstiftaren något vi idag skulle kalla som moralpanik. Moralen låg i att värna äktenskapet genom att fördöma de som ingick sexuella relationer innan äktenskapets ingående. Paniken kan illustreras genom att allt strängare straff och till slut oåterkalleliga straff utdömdes. Nya laga
I denna uppsats behandlas det migrationsrättsliga frihetsberövandet förvarstagande och vilken rättslig domän detta kan anses tillhöra. För att svara på vilken rättslig domän förvarstagande tillhör har jag studerat förvaltningsrättsliga och straffprocessuella frihetsberövanden och de syften som motiverar dessa. Således behandlas tre olika former av frihetsberövanden, förvarstagande enligt utlänningThis thesis examines what legal body detention within migration law is considered belonging to. In order to find this out, I have studied detention within the bodies of administrative- and criminal law, along with the reasons that motivates the different types of detention within these. Three types are examined; migration detention according to the Aliens Act, detention as compulsory care accordin
Trots att bemanningsbranschens utveckling på arbetsmarknaden har ökat de senaste åren har forskningen och kunskapen om bemanningsanställda inte ökat i samma takt. Den psykosociala arbetsmiljön har förändrats de senaste decennierna i och med framväxten av alternativa anställningar. Både den fysiska och psykosociala arbetsmiljön har betonats som viktig för personers hälsa och välbefinnande. I arbetsThe development of temporary agencys on the labormarket has been increasing over the past years, despite of this the research and knowledge about temporary workers has not increased in the same pace. The psychosocial environment has changed the past decades with the emergence of alternative empolyments. The importance of the physical and the psychosocial work environment has been emphasized for th
In current experiments at the high-power laser facility at the Lund Laser Centre, electrons accelerated to hundreds of MeV over short distances by means of laser wakefield acceleration in produced plasmas. To determine the amount of secondary radiation generated when accelerated electrons interact with surrounding materials is of interest to ensure a safe working environment. In this thesis, the
Över tid har våldtäktsbrottet varit ett omdiskuterat ämne, inte minst bland politiker och jurister men även bland befolkningen som helhet. Protester, debatter, nyhetsartiklar och hashtags är inte ovanligt förekommande inom diskussionen. Syftet med förevarande uppsats har varit att ge en övergripande blick över gränserna för det juridiska begreppet våldtäkt och har ämnat att besvara vilka de ursprOver time the crime rape has been a discussed topic, non the least among politicians and jurists but also among the common people. Protests, debates, newsarticles and hashtags are not unusually occuring in the discussion. The object of this essay has been to give an overall look at the boundaries for the legal word rape and aims to anwser where the original boundaries were drawn and how the bound
