Search results

The patterns in dissolved organic carbon (DOC) photo-mineralization along the freshwater continuum from land to sea are poorly known. Specifically, it has not been resolved how the photo-degradation of DOC into CO2 (PD) depends on the combination of intrinsic properties of DOC and extrinsic variables that affect the photo-reactions. We measured PD per unit of absorbed ultraviolet light energy (PD-

Importance: Preterm birth has been associated with cardiometabolic, respiratory, and neuropsychiatric disorders in adulthood. However, the prevalence of survival without any major comorbidities is unknown. Objective: To determine the prevalence of survival without major comorbidities in adulthood among persons born preterm vs full-term. Design, Setting, and Participants: National cohort study of a

Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1 (832/13) cells. Microarray and RNA sequencing data showed that PLCXD3 is among the highly expressed

This article focuses on the negotiated distinction between commercial and non-commercial spheres of life through the phenomenon of lifestyle entrepreneurship. Lifestyle entrepreneurship is a concept used for a form of self-employment, based on the business owner´s own hobby or lifestyle. The article is based on a study of lifestyle enterprising in the tourism and hospitality industries in southern

BACKGROUND: Individuals with mental health problems often need support from vocational rehabilitation professionals in their return-To-work (RTW) process. Research has shown that this support can be deficient, with vocational rehabilitation professionals lacking relevant knowledge and an underlying belief in the individual's ability to resume a working life. More understanding is therefore needed

Complement component C3 is central to the complement system, a humoral effector mechanism of innate immune defense. When activated, C3 covalently binds to target particles, marking them for uptake and clearance by phagocytosis. We now show that C3 also exists within the cytosol where it interacts with ATG16L1, and is therefore involved in the intracellular clearance and recycling of material by ma

LSTM architectures (Hochreiter and Schmidhuber, 1997) have become standard to recognize named entities (NER) in text (Lample et al., 2016; Chiu and Nichols, 2016). Nonetheless, Zhang et al. (2015) recently proposed an approach based on fixed-size ordinally forgetting encoding (FOFE) to translate variable-length contexts into fixed-length features. This encoding method can be used with feed-forward

Epigenetic mechanisms control gene activity and the development of an organism. The epigenome includes DNA methylation, histone modifications, and RNA-mediated processes, and disruption of this balance may cause several pathologies and contribute to obesity and type 2 diabetes (T2D). This Review summarizes epigenetic signatures obtained from human tissues of relevance for metabolism—i.e., adipose

Early empirical studies in labour and urban economics addressing the role of commuting (on, e.g., wages and locational choice) have typically been confined to the use of survey data. Researchers are, however, increasingly getting access to large register databases with detailed information on where individuals live and work. A variety of methods have thus emerged to exploit the geocoded characteri