Objectives This study sought to study the second-generation everolimus-eluting stent (EES) as compared with first-generation sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) in diabetes mellitus (DM) patients. Background There are limited data available comparing clinical outcomes in this setting with EES and SES, whereas studies comparing EES with PES are not powered for low-frequency

Background Comparison of patients with coronary heart disease and controls in genome-wide association studies has revealed several single nucleotide polymorphisms (SNPs) associated with coronary heart disease. We aimed to establish the external validity of these findings and to obtain more precise risk estimates using a prospective cohort design. Methods We tested 13 recently discovered SNPs for a

Background: A hip fracture is a common cause of morbidity, functional disability, and decreased health-related quality of life (HRQOL). With demographic changes showing a growing proportion of older people, hip fractures will be an increasing challenge for healthcare services in the future. Hip fractures threaten the independence of individuals in their everyday lives. In Sweden, more than one thi

Denna doktorsavhandling undersöker samtal om personliga problem i mötet med en specialist i radio. I synnerhet handlar studien om den dynamiska process då förståelse skapas – när upplevelser av personliga bekymmer förklaras och definieras som problem av särskilda slag. Denna meningsskapande process undersöks i detalj så som den utspelar sig i dialoger i radio och mellan programdeltagare och radiolThe dissertation examines how personal troubles are talked about in an encounter with a professional on the public arena of radio broadcasting, where the professional has to meet the challenge of making professional advice not only useful for the person seeking help, but also relevant or interesting for the radio audience. The study explores the dynamic process of shaping an understanding of probl

Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. Clinically, MM is characterized by bone marrow failure, lytic bone lesions, hypercalcemia, and kidney failure. It is preceded by mono

A sustainable development of the built environment asks for changes in urban residents’ mobility patterns. The extensive use of the car contributes to sedentary lifestyle and negative environmental impact in many respects. Children living in urban areas are faced with limits of their independent use of the environment both in terms of travel and outdoor play. Many parents hold favourable attitudes

There is concern over the high risk of cardiovascular complications, hypertensive disorders, and other adverse obstetric outcomes among pregnant women with Turner syndrome (TS). A diagnosis of TS is made in some women late in life or not at all. Spontaneous pregnancies are rare in women with TS and are associated with a high rate of complications, especially miscarriage. The use of assisted reprod

I denna avhandling används samtalsanalys (”conversation analysis”) för att studera ”riskstrategier” i samtal mellan lärare, elever och föräldrar i grundskolan. Materialet består av 80 samtal som insamlats vid två olika tidpunkter: 45 st. inspelade 1992–93 (kvartssamtal, eller den mer formella benämningen enskilda samtal) och ytterligare 35 st. inspelade 2004 (utvecklingssamtal, den benämning som g

As a result of the globalisation of the world economy, many enterprises that previously confined their business activities to national markets are now focusing on broader international markets, thus forming the basis for the establishment of global enterprises. In addition to the extension of markets, these global companies also seek cost reductions through scale economics in logistics, marketing,

E-business is becoming more and more common today. The predictions of future growth give clear indications that companies will use e-business more and more. However in the growth of e-business it has been identified that there is a common lack of understanding in customer needs and logistics. In order to reduce some of this non-understanding this thesis seeks answers to the following question: - H

Background: The longevity for people with intellectual disability (ID) has significantly increased in developed countries during the past decades. Consequently, the incidence of cancer is expected to increase in this group. The aim of the present study was to investigate the prescription of pain medication in older cancer patients with intellectual disability (ID) compared to older patients in the

Importance: High gluten intake during childhood may confer risk of celiac disease. Objectives: To investigate if the amount of gluten intake is associated with celiac disease autoimmunity and celiac disease in genetically at-risk children. Design, Setting, and Participants: The participants in The Environmental Determinants of Diabetes in the Young (TEDDY), a prospective observational birth cohort

BackgroundDense Non Aqueous Phase Liquids (DNAPL) such as chlorinated solvents are common pollutants stemming from different types of industries including dry cleaning facilities, and reports on cases showing serious risk to soil and ground water are frequent on a global scale. DNAPLs are especially problematic as they are denser than water and move down through the groundwater, not always followi

Denna kunskapssammanställning beskriver hur hälsoskadlig värme kan uppstå inomhus, hur den kan identifieras och vilka åtgärder som kan vidtas med fokus på fastighetsägarens ansvar. Sammanställningen är begränsad till befintliga byggnader i Sverige och inkluderar skolor, äldreboenden, lägenheter, förskolor och kontor som är icke-industriella (utan industriella processer som producerar värme). Den p