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A pandemic is a crisis and as such, in many ways, an entirely new situation . It is a situation in which there are scientific as well as societal uncertainties and where the routines of everyday life are overturned . The Covid-19 pandemic has made visible already established social structures and inequalities, but it has also exacerbated existing power relations and vulnerabilities . In this artic
BACKGROUND: Self-management programs are recognized as a valuable approach to supporting people with long-term conditions, such as stroke, in managing their daily lives. Bridges Self-Management (Bridges) focuses on how practitioners interact and support patients' confidence, skills, and knowledge, and it is an example of a complex intervention. Bridges has been developed and used across multiple h
Background: Rectal cancer treatment has improved through important incremental surgical and oncological developments over the past decades. Localized disease is highly treatable with multimodal surgical and oncological therapy. Prognosis is dependent on several factors with tumour stage at diagnosis being the most important. Furthermore, curative treatment is highly dependent on radical surgical r
The discovery of TRPV1 as a receptor for capsaicin, the pungent ingredient in chili pepper, and noxious heat has triggered immense research on the role of TRP channels as polymodal receptors in sensory neuronal signaling. The rich abundance of TRPV1 in nociceptive primary afferents and its involvement in inflammatory and neuropathic pain encouraged the development of analgesics acting on TRPV1. Ho
A patient with multiple endocrine neoplasia 2A (MEN2A) and a suspicion of metastasized pheochromocytoma, underwent multi-molecular positron emission tomography (PET) imaging with the recently presented radiopharmaceutical [18F]-metafluorobenzylguanidine (mFBG), [68Ga]Ga-DOTA-TOC and [18F]F-dihydroxyphenylalanine (DOPA) as well as scintigraphy with [123I]-metaiodobenzylguanidine (mIBG). The methods
This study examines whether unstructured and structured activities interact in their association with delinquency and cannabis use. We hypothesize that unstructured activities are more strongly associated with delinquency and cannabis use for those who are less engaged in structured activities. Data are drawn from three nationally representative self-report studies conducted between 2005 and 2011
Introduction Neoadjuvant therapy is the standard of care for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC). Studies on first-generation antibody-drug conjugates, such as trastuzumab emtansine (T-DM1), showed equal or slightly lower efficacy than chemotherapy combined with dual HER2 blockade. Trastuzumab deruxtecan (T-DXd) is a next-generation conjugat
Over the past century, Syria and the broader Middle East and North Africa (MENA) region have undergone profound demographic and economic transformations, yet they remain marked by deep regional, ethnic, and gender-based inequalities. These divisions have shaped development trajectories and contributed to social fragmentation, while successive waves of migration carried these dynamics abroad, from
IMPORTANCE Risk stratification strategies in primary prevention of coronary events lack precision. OBJECTIVE To determine whether prediction of first coronary events is improved by adding information on coronary atherosclerosis from coronary computed tomography angiography (CCTA) to a model using the pooled cohort equation (PCE) risk score tool and the coronary artery calcification score (CACS). D
Background: Air pollution has been linked to breast cancer risk, but previous studies have seldom considered specific exposure windows, like pregnancy. During pregnancy the breast undergoes substantial changes and exposures may have a stronger impact than if they occurred during other time periods. This study aims to identify associations between ambient air pollution exposure during pregnancy and
I uppsatsen undersöks flyktingdefinitionen i ljuset av intersektionalitet som teoretiskt ramverk utifrån 4 kap. 1 § utlänningslagen och mot bakgrund av artikel 1A(2) i flyktingkonventionen. Analysen omfattar flyktingdefinitionen i gällande rätt och dess tillämpning i svenska migrationsdomstolar. Fokus är på de två elementen förföljelsegrunderna och förföljelse på kumulativa grunder i definitionen.
Background: The clinical management of ER-positive/HER2-negative (ERpHER2n) breast cancer is complicated by a heterogeneous patient population, with some patients exhibiting endocrine resistance and an increased risk of recurrence. Among these high-risk subgroups, ERpHER2n Basal-like (ERpHER2n-Basal) breast cancer, as defined by PAM50 gene expression subtyping, remains poorly characterized due to
The textile industry generates vast wastewater containing synthetic dyes and polymeric additives like poly(vinyl alcohol) (PVA), which pose serious environmental challenges. Conventional treatment methods struggle to remove these contaminants while enabling resource recovery. PVA, widely used as a textile sizing agent, increases treatment complexity, while reactive dyes like Reactive Yellow 145 ar
Uppsatsen behandlar domstolens skyldighet att utöva materiell processledning i förhållande till parternas åberopade rättsfakta i dispositiva tvistemål. Utgångspunkten är den spänning som råder mellan dispositionsprincipen, enligt vilken parterna bestämmer processens ram, och domstolens ansvar för att genom materiell processledning klarlägga processmaterialet. Rättegångsbalken ger begränsad väglednThe thesis examines the court’s duty to exercise direction of proceedings in relation to the parties’ referred circumstances in civil cases amenable to out-of-court settlement. The point of departure is the tension between the principle of party disposition, according to which the parties determine the framework of the proceedings, and the court’s responsibility to clarify the procedural material.
När metoo-rörelsen fick sitt genombrott i Sverige år 2017 förändrades det offentliga samtalet på internet. Sociala medier används under denna period i stor utsträckning för att dela personliga berättelser. I ett av de mest uppmärksammade målen publicerade en journalist ett flertal inlägg på sociala medier där en medieman utpekades som våldtäktsman. Publiceringarna resulterade i en fällande dom för
This study investigates, through the lens of the humanistic vita with its historiobiographical structure, how Claes Örnhielm, in Vita Ponti de la Gardie, formulates a systematic response to contemporary accusations concerning the legitimacy of the De la Gardie family’s noble origins. Through an integrated examination of the work’s frontispiece, genealogical diagram, textual genealogy and wider nar
Säkerhetsläget i Europa har förändrats drastiskt under de senaste åren, med de två största förändringarna i Rysslands invasion av Ukraina, och NATO:s expandering med Sverige och Finland som nya medlemsstater. Den ökade militariseringen i Europa har också resulterat i att en gammal fråga nu igen dykt upp i den allmänna debatten, nämligen frågan om Åland borde remili-tariseras i syfte att säkra Öste
Utgångspunkten i svensk avtalsrätt är att rättsverkningar förutsätter aktiva handlingar. Avtal anses normalt uppkomma genom ett utbyte av samstämmiga viljeförklaringar i form av anbud och accept. Passivitet, dvs. underlåtenhet att handla, leder som huvudregel inte till avtalsbundenhet. Denna ordning vilar på avtalsfriheten och viljeprincipen, enligt vilken en part endast blir bunden till vad denne
