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BALDR : A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus

Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have built BALDR, an automated pipeline for biomarker comparison and prioritization in the context of diabe

Floristic Legacy of English-Style Landscape Gardens and the Use of Imported Grass Seed for Sowing under Trees

During WWII, the botanist Hylander (1943, 1949) studied the floristic composition of lawns in 249 landscape gardens mostly in Sweden and concluded that they all harboured multiple, but largely the same, non-native species and genotypes that had most likely been introduced together by the sowing of some im- ported grass seed mix. As demonstrated by the later additions by, for example, Ohlsén (1947)

Var tillverkades skånekannan?

This paper revisits the glazed redware Scanian jug, brought to the fore by Kulturen archaeologist Anders W. Mårtensson in 1973. Characterized by its faceted base and distinct handle, the jug stands out from its contemporaries. This brief paper presents new chemical data for the Scanian jug, its most common rim forms and a discussion on its area of production. So far, no medieval ceramic production

Fattigvård, diakoni och välfärdstjänster - från restriktioner till konkurrensutsättning

The Church has been a dominant actor in the history of care and social support, but it met several restrictions during the 20th Century. The Church of Sweden now has,since the separation from the state A.D. 2000, the possibility to act as a "welfare entrepreneur". But the willingness to do so seems limited. Even if innovative examples are seen the parishes hesitate for organisational and ideologic

Firm performance in the periphery: on the relation between firm-internal knowledge and local knowledge-spillovers

Firm performance in the periphery: on the relation between firm-internal knowledge and local knowledge spillovers. Regional Studies. One of the most established arguments in regional studies is that knowledge dynamics shape thegeography of economic activities and, more specifically, that knowledge-intensive activities benefit from collocation due to knowledge spillovers, local buzz and access to l

Biomarker Discovery in Cancer using Affinity Proteomics - Studies of B-cell lymphomas and Breast Cancer

The continual increase in incidence of cancer has created an urgent need for improved methods for diagnosis, prognosis and/or treatment. In this context, the field of biomarker research has expanded immensely during the last few years. This thesis, based on four original papers, revolves around protein biomarker discovery in cancer. For this purpose, an in-house design recombinant antibody microar

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic links have remained elusive. T1D results from autoimmune destruction of pancreatic beta cells, whereas beta cell failure in T2D is delayed and progressive. Here we find a new genetic component of diabetes susceptibility in T1D non-obese diabetic (NOD) mice, identifying immune-independent beta cell frag

Discourse for Normalising What? The Learning Organization and the Workplace Trade Union Response

Recent critics of organizational learning and its normative offshoot the ‘learning organization’ have posited that conceptualisations of organizations based on knowledge and learning constitute a rhetorical device enabling elites to assert different forms of control through a new ‘normalising discourse’. The paper, whilst welcoming such critique, nevertheless asks whether it is adequate to dismiss

Corporate Governance in Scandinavia: Comparing Networks and Formal Institutions

This article addresses the role of formal institutions and informal networks on corporate governance practices. The existing corporate governance literature has mostly examined the formal institutions, such as the effect of legal systems. Our contribution is to consider the effect of informal “small world” characteristics of ownership and board networks. We use the case of Scandinavia (Denmark, No

Learning Outcomes in Doctoral Education – Achieved and Assessed?

The development of the European Higher Education Area (EHEA) is firmly rooted in the idea of higher education (HE) as the cornerstone of a knowledge-based society. Throughout Europe, HE bodies are addressing issues of quality, mobility, employability and lifelong learning. HE agencies and institutions alike are working hard to harmonise European degrees and apply quality assurance standards (ESG,

The Parish in the Audit Society

What happens when global market-oriented models for auditing and quality assessment are taken up by local parishes? The paper is based on case studies where a number of parishes and auditing models provide the object of study. Parishes are to some extent restrictive about embracing new ideas on auditing and quality control. With assistance from neo-institutional theory it can be shown that the co

Simulation-based Analysis of Co-dispatching in Prehospital Stroke Care

A mobile stroke unit (MSU) is a specialized ambulance, enabling to shorten the time to diagnosis and treatment for stroke patients. In the current paper, we present a simulation-based approach to study the potential impacts of collaborative use of regular ambulances and MSUs in prehospital transportation for stroke patients, denoted as co-dispatching. We integrated a co-dispatch policy in an exist