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This study reports on a study from 2008 of overall mobility patterns among older people and the mobility patterns of those in transition from a two person household to a one person household. The purpose of the study was to explore the mobility patterns of those in transition from a two-person household to a one-person household in relation to the overall patterns of mobility of the older people.
This doctoral dissertation was driven by an inspiration to study how employees behave toward each other from an interactive perspective where all members of an organization are considered active contributors. Employeeship holds this perspective and acknowledges the importance of productive relationships. The objective of this dissertation is to contribute to the conceptual and methodological devel
Computerization of control room functions changes the work for the operators to a great extent. Their mental picture of the process, their possibilities to control the process for productivity and quality, the work content, the physical and the social working environment are examples of conditions which are changed one way or another. In order to be able to control the computerization process in a
Considerable economic as well as environmental benefits can be achieved when appropriate industrial waste management is implemented. The objective of this study was to find a method of organizing a waste management system and of obtaining an overview of the whole system. The method proposed emphasizes the optimization of waste management with regard to energy, economy and environmental impact in s
Autoimmune (type 1) diabetes (AI-DM) is a multistage disorder. Children are born genetically predisposed to putative environmental exposures. These trigger an aggressive, selective and chronic autoimmune response against the pancreatic islet beta cells. This stage is marked by autoantibodies against insulin, glutamic acid decarboxylase (GAD65), IA-2 and the ZnT8 transporter. Progression to clinica
The focus of this project has been to find a method on how to do production improvements systematically in the case of manufacturing by means of metal cutting operations. Typically every company determines their cutting data with the help of previous experiences as well as recommendations made by the tool manufacturers. These chosen cutting data may be the optimal settings for the specific operati
Impaired albumin reabsorption by proximal tubular epithelial cells (PTECs) has been highlighted in diabetic nephropathy (DN), but little is known about the underlying molecular mechanisms. Here we find that ORAI1-3, are preferentially expressed in PTECs and downregulated in patients with DN. Hyperglycemia or blockade of insulin signaling reduces the expression of ORAI1-3. Inhibition of ORAI channe
The increasing biofuel production from agricultural crops has been suggested to cause indirect land use change (iLUC). This increases interest in biofuel feedstocks that qualify as iLUC-free: (1) residues without a market, (2) crops from previously unused arable land, (3) additional crops and (4) biomass from intensified production. In the present study, biofuel potential from such feedstocks was
The lack of treatments during the recent Ebola and Zika outbreaks dramatically exposed the vulnerability of the global health system and the dire consequences thereof. But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). A growing number of microbial organisms are becoming resistant to availab
The rise of ICT and the shift toward jobs with more flexibility in working hours and places of work sparked popular debates about potential for a ‘rural renaissance’. A key argument was that there are increasing possibilities to live in the countryside while being employed in large cities. This paper uses data spanning two decades to examine trends in and characteristics of employee–employer ties
This experimental study adapts a usage-based perspective on L2 acquisition (Bybee 2008; Ellis 2008) and focuses on the production of French subject-verb (SV) agreement in number (singular vs. plural). Previous studies show that the acquisition of this agreement is a long and gradual process in L2 French (Bartning & Schlyter 2004; Prévost 2009; Michot 2015). This study examines the influence of
Glucagon secretion by pancreatic α-cells is triggered by hypoglycemia and suppressed by high glucose levels; impaired suppression of glucagon secretion is a hallmark of both type 1 and type 2 diabetes. Here, we show that α-cell glucokinase (Gck) plays a role in the control of glucagon secretion. Using mice with α-cell-specific inactivation of Gck (αGckKO mice), we find that glucokinase is required
This chapter will analyse the Trade secret Directive from a technological informed legal perspective, looking at the possibilities and scope of protection that it offers for knowledge based activities and business models. It opens by restating the basic yet important fact that “Information is power”. Asymmetries in information are a fundamental transaction cost and in this sense informational qual
