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Associations of perinatal characteristics with endometriosis : a nationwide birth cohort study
BACKGROUND: Perinatal characteristics are associated with subsequent risk of several chronic diseases. Previous studies regarding endometriosis were based on small samples and retrospective data and were limited by unmeasured confounding bias, leading to conflicting and inconclusive findings. We investigated the associations of maternal and birth characteristics with risk of endometriosis among Sw
Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness
OBJECTIVE: While existing evidence supports beneficial cardiovascular effects of glucagon-like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic peptide (GIP) and/or signaling via the GIP receptor may have untoward cardiovascular effects. Indeed, recent studies show that fasting physiological GIP levels are associated with total mortality and cardiovascular mortalit
Pregnancy-associated plasma protein-A2 levels are increased in early-pregnancy gestational diabetes : a novel biomarker for early risk estimation
Aim: To determine whether pregnancy-associated plasma protein-A2 levels are increased in early pregnancies complicated by gestational diabetes and whether gestation age influences levels. The possible use of pregnancy-associated plasma protein-A2 as a pre-screening biomarker to reduce the need for performing oral glucose tolerance tests in pregnant women was also investigated. Methods: Pregnant wo
Purine Metabolites and Carnitine Biosynthesis Intermediates Are Biomarkers for Incident Type 2 Diabetes
CONTEXT: Metabolomics has the potential to generate biomarkers that can facilitate understanding relevant pathways in the pathophysiology of type 2 diabetes (T2DM). METHODS: Nontargeted metabolomics was performed, via liquid chromatography-mass spectrometry, in a discovery case-cohort study from the Malmö Preventive Project (MPP), which consisted of 698 metabolically healthy participants, of whom
Märta Strömberg (1921–2012)
Biographical essay on Märta Strömberg, professor of Archaeology in Lund. She was one of the first female archaeologists that took place in the university world. She became a committed mentor for generations of students, doctoral students and colleagues. Her archaeological investigations of the Stone Age megalithic tombs, the Bronze Age and the Iron Age grave fields and settlements became methodolo
Culprit vessel: impact on short-term and long-term prognosis in patients with ST-elevation myocardial infarction.
Background ST-elevation myocardial infarction (STEMI) occurs as a result of rupture of an atherosclerotic plaque in the coronary arteries. Limited data exist regarding the impact of culprit coronary vessel on hard clinical event rates. This study investigated the impact of culprit vessel on outcomes after primary percutaneous coronary intervention (PCI) of STEMI.Methods A total of 29 832 previousl
Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity
Essentials Knowledge of genetic regulators of plasma factor VII activating protease (FSAP) levels is limited. We performed a genome-wide analysis of variants influencing FSAP activity in Scandinavian cohorts. We replicated an association for Marburg-1 and identified an association for a HABP2 stop variant. We identified a novel locus near ADCY2 as a potential additional regulator of FSAP activity.
Bygga - Bruka - Riva : Energianvändning i småhus ur ett kretsloppsperspektiv
Detta arbete avgränsas till att behandla energianvändning i småhus. Studien omfattar tre småhus som byggts för utställningen Bo92 i Örebro. Syftet med studien är att beräkna och ta fram kunskaper om den totala energiåtgången under en byggnads hela livscykel. Användningstiden för husen är antagen till 50 år.
An investigation of serum concentration of apoM as a potential MODY3 marker using a novel ELISA.
Plasma copeptin and the risk of diabetes mellitus.
Gambling disorder, increased mortality, suicidality, and associated comorbidity : A longitudinal nationwide register study
BACKGROUND AND AIMS: Gambling disorder (GD) appears to be an independent risk factor for suicide, and all-cause mortality has been sparsely studied in patients with GD. This study aims to explore mortality and suicide rates in individuals with GD compared to the general population as well as explore risk factors associated with all-cause mortality and suicide mortality. METHODS: This is a nationwi
Alcohol Availability and Onset and Recurrence of Alcohol Use Disorder : Examination in a Longitudinal Cohort with Cosibling Analysis
Background: Recent reviews of associations of alcohol availability with alcohol outcomes suggest findings are highly inconsistent and highlight a lack of longitudinal and causal evidence. Effect modification (moderation or statistical interaction), which could contribute to the inconsistent picture in the existing literature, has not been systematically assessed. We examined associations of alcoho
A machine learning approach to fault detection in district heating substations
Convenient Food for Baby: A Study of Weaning as a Social Practice
This article reports findings from a study of weaning from a perspective informed by practice theory. The overall aim is to examine how parents integrate convenience baby food into their everyday feeding practices. The focus is the embedding of convenience baby foods in the routines and rhythms of everyday life and the “do-ability” of different practices. The study is based on fieldwork with ninet
Early and late signs that precede dying among older persons in nursing homes: the multidisciplinary team’s perspective
Characterization of the Multi-Blade 10B-based detector at the CRISP reflectometer at ISIS for neutron reflectometry at ESS
The Multi-Blade is a Boron-10-based gaseous thermal neutron detector developed to face the challenge arising in neutron reflectometry at neutron sources. Neutron reflectometers are challenging instruments in terms of instantaneous counting rate and spatial resolution. This detector has been designed according to the requirements given by the reflectometers at the European Spallation Source (ESS) i
Collection of microlevel Safety and efficiency Indicators with Automated Video Analysis
This paper revises the theoretical grounds for relation of the micro-level behaviour indicators to the safety and efficiency (level-of service) of the local traffic system. Automated video analysis is suggested as a tool for collection of the individual data about road users driving trajectories and speeds and interaction with other road users. The authors describe the current state of the video a
The development of a brief screener for autism using item response theory
Background: Brief screening instruments focusing on autism spectrum disorder (ASD) that can be administered in primary care are scarce; there is a need for shorter and more precise instruments. The Autism-Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated for ASD reporting excellent validity. This study aims to determine the psychometric properties of each item in
