The early design stage of a building is decisive for describing the concept of the HVAC system. Designers and practitioners can adjust and optimize the design during this stage as it provides them with enough resilience to adapt new changes. In practice, a well-defined optimization process is essentially required in order to achieve the project’s goals within a reasonable time span. These goals va

Electronic publishing and institutional archives – a scholarship report from CaliforniaIn June 2005 Linda Gustafsson and Kristina Lindgren had the opportunity to make a one week visit to the library at Caltech University, Pasadena in California. The aim was to see how the library staff worked with e-publishing together with the researchers at the campus. As researchers are an important user group

Background: Diet is a determinant of gut microbiota. Both diet and gut microbiota have been linked to metabolic diseases. Objective: We aimed to examine data-driven food patterns in relation to the prevalence of prediabetes and gut microbiota composition and food pattern-associated bacteria in relation to prediabetes. Methods: Food patterns were extracted using principal component analysis in 1726

Introduction: Treatment after Anterior Cruciate Ligament (ACL) injury includes physical therapist supervised neuromuscular training, with or without surgical reconstruction, aiming to improve patient-reported outcomes and muscle function. Despite this treatment, sensorimotor deficiencies persist, possibly constituting a contributing factor for risk of re-injury, early-onset osteoarthritis, and a l

I föreliggande studie har ekonomerna ombetts att besvara ett antal påstående om sin egen arbetssituation men också hur de uppfattar ”digitaliseringstillståndet” i sina kommunala och regionala organisationer. Utifrån dessa svar och kompletterande intervjuer konstateras det i rapporten bland annat att det tas påtagliga digitaliseringssteg i Sveriges kommuner och regioner, men att det går relativt sa

Background: In early stage chronic obstructive pulmonary disease (COPD), dyspnea has been reported as the main symptom; but at the end of life, patients dying from COPD have a heavy symptom burden. Still, specialist palliative care is seldom offered to patients with COPD; they more often receive end of life care in hospitals. Furthermore, symptoms, symptom relief and care activities in the last we

The discovery of TRPV1 as a receptor for capsaicin, the pungent ingredient in chili pepper, and noxious heat has triggered immense research on the role of TRP channels as polymodal receptors in sensory neuronal signaling. The rich abundance of TRPV1 in nociceptive primary afferents and its involvement in inflammatory and neuropathic pain encouraged the development of analgesics acting on TRPV1. Ho

In 2006 a genetic signal within the gene encoding transcription factor 7-like 2 (TCF7L2) was first reported to be associated with type 2 diabetes. Since then multiple genome-wide association studies have revealed this signal to be among the most strongest associations reported with this disease to date. Furthermore, multiple studies around the world have revealed the global relevance of this locus

The aims and goals of the article are to discuss how typology can be misleading in the study of archaeological artefacts. The discussion is exemplified using transverse arrowheads in the late Scandinavian Mesolithic. One contemporary, and often accepted, typology of transverse arrowheads is presented along with a summary of typological development and debates. The concept of curation, first introduc