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Hur påverkar ökad efterfrågan av närproducerade varor Sveriges import?

As consumer interest in locally produced food increases, farmers and other producers wants to marketing their products as locally produced. A range of different certifications for environmentally friendly food have appeared. More costumers want to buy their food directly from the farmer at the same time as a more and more globalized world advocates free trade and removal of barriers to trade. By u

Osäkerheter i variabler vid riskanalyser och brandteknisk dimensionering

The aim of this report is to present some of the variable uncertainties associated with the dimensioning of fire protection in buildings and risk analysis in buildings (with respect to fire). A method for assessing the fire frequency in a building is presented along with examples of how the assessed fire frequency can be improved using fire data from a specific building. The probability of differe

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

Reduced insulin release has been linked to defect exocytosis in β-cells. However, whether expression of genes suggested to be involved in the exocytotic process (exocytotic genes) is altered in pancreatic islets from patients with type 2 diabetes (T2D), and correlate to insulin secretion, needs to be further investigated. Analysing expression levels of 23 exocytotic genes using microarray revealed

Lim Domain Binding 2: A Key Driver of Transendothelial Migration of Leukocytes and Atherosclerosis.

Using a multitissue, genome-wide gene expression approach, we recently identified a gene module linked to the extent of human atherosclerosis. This atherosclerosis module was enriched with inherited risk for coronary and carotid artery disease (CAD) and overlapped with genes in the transendothelial migration of leukocyte (TEML) pathway. Among the atherosclerosis module genes, the transcription cof

Rye bran alkylresorcinols suppress adipocyte lipolysis and hormone-sensitive lipase activity

The effects of alkylresorcinols (ARs) isolated from rye bran on adipocyte lipolysis, hormone-sensitive lipase activity and phosphorylation and on phosphorylation of protein kinase A substrates were studied. Preincubation with ARs for 18 h suppressed catecholamine-stimulated lipolysis in 3T3-L1 adipocytes. Furthermore, phosphorylation of hormone-sensitive lipase (HSL), a key lipase responsible for

Increased aldehyde-modification of collagen type IV in symptomatic plaques - A possible cause of endothelial dysfunction.

Subendothelial LDL-adhesion and its subsequent oxidation are considered as key events in the development of atherosclerotic lesions. During oxidation of LDL, reactive aldehydes such as malondialdehyde (MDA) are formed, which modify apolipoprotein B100. However, the possibility that these reactive aldehydes could leak out of the LDL-particle and modify surrounding extracellular matrix proteins has

Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.

Adipose tissue has an important function in total energy homeostasis and its dysregulation may contribute to life-style related diseases such as type 2 diabetes, cancer and cardiovascular diseases. The aim of this study was to investigate genome-wide mRNA expression in adipose tissue in healthy men before and after an exercise intervention to identify genes or pathways that mediate the beneficial

Gestational Age at Birth and Mortality in Young Adulthood EDITORIAL COMMENT

Preterm birth is associated with increased rates of neonatal and infant mortality. It has been hypothesized that gestational age at birth may also be associated with increased mortality rates in adulthood, but to date, no studies have demonstrated this relationship. This national cohort study investigated the association between gestational age at birth and mortality in young adulthood. Data obtai

Inflectional features and clausal structure

This paper discusses the relation between verbal inflection and clausal structure, making the claim, based on evidence from Icelandic finite verb inflection, that formal verbal features, such as Number, Person, Tense and Mood, each represents (or corresponds to) a functional head in clausal structure. More generally, the paper claims that there is a one-to-one correspondance between formal feature

The role of public policy in advancement of product service systems

This article discusses developments in the area of product service systems (PSS) and the need to facilitate the proliferation of the PSS approach through public policies. The article argues that policies that establish the framework conditions for environmental improvement are preferable to detailed legislation as they favour environmentally superior PSS. However, there is also a need for more spe