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Autoantigen discovery is a critical challenge for the understanding and diagnosis of autoimmune diseases. While autoantibody markers in current clinical use have been identified through studies focused on individual disorders, we postulated that a reverse approach starting with a putative autoantigen to explore multiple disorders might hold promise. We here targeted the epidermal protein transglut

Growth-dependent welfare states contribute to climate emergency. The ecological economics, degrowth, and sustainable welfare literatures demonstrate that to re-embed Western production and consumption patterns in environmental limits, an encompassing social-ecological transformation would need to be initiated very soon. This article focuses on the potential roles of the welfare state and social po

Uppsatsen beskriver omfattningen av momskaruseller och hur omvänd skattskyldighet i vidare utsträckning används för att motverka dessa typer av bedrägerier. EU-rättens omfattning spelar stor roll på mervärdesskattens område och har därför även utretts inom ramen för denna uppsats. Gällande omvänd skattskyldighet har det på senare år tillkommit flera möjligheter för EU:s medlemsstater att införa olThe focus of the thesis is to describe the scope of carousell fraud and how reverse charge mechanism is used as a preventable measure. Union law plays a big part in the way member states are able to create legislation regarding the issue and has therefore generally been examined within the scope of this the-sis. Regarding reverse charge mechanism there have been multiple changes in possibilities o

Public health care systems face major challenges. The burden of resource constraints and continuous demands of rationings urge decision makers in countries like Sweden, Norway and the UK to find new financial solutions. One proposal that has been put forward is co-payments. In this presentation we explore ethical problems associated with co-payments in publicly funded health care systems. The issu

Becoming a father, especially for the first time, can present changes in men's identity and in the relationship with their partner. Affinity within the family and participation in the whole process of pregnancy, childbirth and the postnatal period are important for fathers' sense of postnatal security. The fathers want to be already prepared before birth for the early postnatal period. Willingness

That society divides its members into females and males is the point of departure for much research on gender and language and yet the situated accomplishment of the primordial sex categorisation of the newborn child has not attracted much scholarly attention. The present study fills this research gap by exploring the interactional organisation of sex assignment in a corpus of 67 video recordings

While priority setting for research, development and innovation (RDI) traditionally focuses on which thematic areas should be supported, less is known about how such goals are implemented on the agency level. Key challenges are how to translate broad priorities into programs and projects, how to govern the knowledge base, and how to handle organizational tensions during implementation. Many of the

Type 2 diabetes is a complex trait with both environmental and hereditary factors contributing to the overall pathogenesis. One link between genes, environment, and disease is epigenetics influencing gene transcription and, consequently, organ function. Genome-wide studies have shown altered DNA methylation in tissues important for glucose homeostasis including pancreas, liver, skeletal muscle, an

The overall theme for this thesis is Children and Youth Geography and it uses the Convention on the Rights of the Child as point of departure. By conducting both a self-administrative questionnaire and semi-structured interviews, this thesis explores in what ways the Local follow up of youth policy (lokal uppföljning av ungdomspolitiken, LUPP) can contribute to developing children’s and youths’ in

The migration patterns of newly graduated students have implications for regional development, as the attraction and retention of high-educated individuals is important for the innovation and productivity of the regional labor market. Moreover, imbalances in the migration flows may create or amplify regional discrepancies. The study focuses on the demographic characteristics of the graduates from

Electric vehicle (EV) charging may be used in aggregation as virtual batteries to provide a frequency regulating service to the power grid. The service is sold on the Frequency Containment Reserve (FCR) markets, and is traded one and two days ahead. Forecasts of charging patterns are essential to reliably provide this ancillary service. The thesis aims to build a generalized model for forecasting