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Glucagon normalises disposition index by increasing acute insulin response to intravenous glucose: comparison with incretins

Risk of Celiac Disease According to HLA Haplotype and Country REPLY

Shifting the paradigm of islet inflammation-good guy or bad guy?

Platelets play an important role in acute pancreatitis

At high risk for early withdrawal: using a cumulative risk model to increase retention in the first year of the TEDDY study.

Multinational Firms, Acquisitions, and Job Tasks

Atherosclerosis: cell biology and lipoproteins.

The neuro-incretin concept.

Depleting T cells in newly diagnosed autoimmune (type 1) diabetes--are we getting anywhere?

A new reimbursement system for innovative pharmaceuticals combining value-based and free market pricing.

Degradation of GIP but not of GLP-1 is reduced after protein ingestion in obese subjects

Determinants of maternal and fetal exposure and temporal trends of perfluorinated compounds.

In recent years, some perfluorinated compounds (PFCs) have been identified as potentially hazardous substances which are harmful to the environment and human health. According to limited data, PFC levels in humans could be influenced by several determinants. However, the findings are inconsistent. In the present study, perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and perfluoron

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Reply to Bastard JP, Rabasa-Lhoret R, Laville M and Disse E [letter]

Active CFTR channels are important for insulin- and glucagon secretion

The Islet and Metabolism Keep Time

Asthma incidence in children growing up close to traffic: a registry-based birth cohort

Background: Recent reviews conclude an association between traffic-related pollution and incidence of asthma in children, but not all studies agree. Studies have almost exclusively relied on parental-reported symptoms or parental-reported diagnoses of asthma and wheeze. Our aim was to investigate if traffic exposure is associated with higher incidence of early onset asthma, using registry-based ou

Clinical Aspects of Pediatric Head Injury

Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

There are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. hyperglucagonemia, for the development of beta-cell dysfunction in pre-diabetic mice. We found that i

Intakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism.

A high intake of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), has been associated with reduced levels of blood pressure (BP). Their antihypertensive action may be due to the reduction of the ω-6/ω-3 ratio and the resulting competitive effect of ω-3 as compared to arachidonic acid (an ω-6 PUFA) as a substrate of cytochrome P450 (CYP450) enzymes involved in the production of vasoactive mediators

Lower Limb Amputation in Patients with Vascular Disease