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To examine if overall diet quality is associated with cellular and soluble biomarkers of systemic inflammation in middle-aged individuals.

Preclinical studies in mice suggest that the natural killer cell receptor NKp46 may be a new molecular target for delaying the progression of type 1 diabetes by interfering with unexpected natural killer cell-mediated recognition of pancreatic beta cells.

In a ‘greying world’ with aging populations, falls in the elderly are a challenge to the health care system as they are associated with substantial mortality and morbidity. Apart from physical injuries, the consequences of falls are broad, with additional psychological and social consequences. The overall objective of this dissertation was to study falls and related risk factors, predictors, and c

There is currently a dramatic and global increase in obesity, type 2 diabetes (T2D) and associated metabolic disorders. T2D can be delayed or prevented in individuals at risk and identifying and developing new food concepts for the prevention of obesity and T2D is of utmost importance. This thesis describes our work on exploring new food concepts for the prevention of T2D. We have used 3T3-L1 adip

Multiple genetic variants have been reliably associated with obesity-related traits in Europeans, but little is known about their associations and interactions with lifestyle factors in South Asians.

Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. Atherosclerosis is a complex disease where both autoimmune responses towards atherosclerosis-related antigens and smooth muscle repair responses play important roles. This thesis con

I såväl media som inom myndigheter och organisationer har det under de senaste åren i allt högre grad uppmärksammats att migrerande arbetskraft inom jordbruket/den gröna näringen eventuellt används på ett sätt som kan strida mot arbetsrättsliga och sociala regleringar.Avsikten med föreliggande studie är framförallt att sammanställa den forskning som finns avseende olika arbetslivs- och arbetsmiljö

One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv

This thesis deals with conodont biostratigraphy and palaeoecology in the Darriwilian (Middle Ordovician) of Baltoscandia, with focus on limestone strata showing traces of the ~ 470 Ma L-chondrite parent body break-up. The evidence for this cosmic event includes abundant centimeter to decimeter-sized fossil meteorites and elevated levels of sediment-dispersed extraterrestrial L-type chromite found

Defective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. T2D research has in recent years invested tremendous efforts in identifying new risk variants for the disease. It has proven t

This paper discusses verbs like help, that takes dative case on its object in the Germanic languages with morphological case. In this paper I discuss whether the loss of morphological case in English and mainland Scandinavian had any influence on the argument structure of the VP headed by help-type of verbs.