Filetype
Besides individual characteristics, people born in the same country may present a related pattern of health status and health care utilisation, perhaps because they share a number of socioeconomic and cultural characteristics in addition to their common geographic origin and language. Rather than using simple ethnical or geographical categories, we apply multilevel regression analysis with individ
Leisure Activities in Rheumatoid Arthritis. Associated Factors and Assessment. Leisure activities were considered to give intrinsic pleasure, meaning and value to life already in ancient Greek. It was also performed for its own sake and not by consideration of any external rewards. In the beginning of the 20th century leisure was only possible for wealthy people who could occupy themselves with n
Background and Aims: Differences in the clinical care of patients have been explained through the concept of practice variation, that is, the occurrence of established local medical procedures that varies between geographic areas. The primary measures introduced to eliminate undesirable differences in medical care are the introduction of medical guidelines and economical incentives that rewards th
The incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thesis was to explore the role of DNA methylation and common genetic variation on glucose metabolism a
Primary Sjögren´s syndrome (primary SS) is a systemic autoimmune rheumatic disease characterized by lymphocytic infiltrations in the exocrine glands leading to classic dryness complaints such as dry eyes and dry mouth. Non-exocrine complaints also occur, e.g. fatigue, myalgia and arthralgia, as well as disturbed mood. The overall purpose of this work was, from a physiotherapeutic perspective, to i
This dissertation deals with personal privacy in working life. Humans have legitimate expectations and claims to respect for and non-interference with personal privacy in many areas and stages of life. The work place is just one of them. The point departure when dealing with privacy matters at the workplace is primarily the claim by individual employees to respect for and non-interference with the
Polycyclic aromatic hydrocarbons (PAHs) are a group of organic pollutants of great environmental concern, due to their toxicity, carcinogenicity and long persistence in the environment. To determine the potential risk associated with PAHs released from contaminated soil or waste materials, knowledge is required on the leachable concentrations of PAHs and the amounts available for release. The obj
To understand whether cerebrovascular events, a major complication of atherosclerosis, are associated with any specific DNA methylation changes in the carotid plaque.
What are the effects of liraglutide, an incretin based treatment, on glycaemic control in people with type 2 diabetes treated with multiple daily insulin injections?
Palaeomagnetic studies of continuous geological archives and archaeological artefacts are required to reconstruct geomagnetic field changes beyond the range of historical observations. In this thesis I assess the reliability of sedimentary palaeomagnetic data and Holocene dipole field reconstructions. New palaeomagnetic records are presented from a maar crater lake in New Zealand and a post-glacia
Defective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. T2D research has in recent years invested tremendous efforts in identifying new risk variants for the disease. It has proven t
