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Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci

Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of upper gastrointestinal obstruction during infancy. A multifactorial background of the disease is well established. Multiple susceptibility loci including the neuronal nitric oxide synthase (NOS1) gene have previously been linked to IHPS, but contradictory results of linkage studies in different materials indicate genetic heterogen

Translation and cultural adaptation of the Integrated Palliative care Outcome Scale including cognitive interviewing with patients and staff

Background: To expand our clinical and scientific knowledge about holistic outcomes within palliative care, there is a need for agreed-upon patient-reported outcome measures. These patient-reported outcome measures then require translation and cultural adaptation, either from country-specific languages to English, or the other way around. The aim of this study was to translate and cross-culturally

The Regulatory Effect on the Performance of Financial Analysts: : Time Series from Two Different Legal Systems

The focus of this paper is the relationship between regulatory settings and financial analysts’ performance, which is examined by studying the level of shareholder protection and the performance of financial analysts in two countries with different legal origins. By using a newly constructed index to measure shareholder protection, we are able to analyze how changes in shareholder protection over

Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study

Statins, commonly used to treat hypercholesterolemia, have also been proposed as anti-cancer agents. The identification of a predictive marker is essential. The 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (HMGCR), which is inhibited by statins, might serve as such a marker. Thorough antibody validation was performed for four different HMGCR antibodies. Tumor expression of HMGCR (#AMAb90619, CL

Domstolsprövning av förvaltningsbeslut. Svensk, dansk och österrikisk rätt i komparativ belysning.

Denna avhandling omfattar en komparativ studie av systemen för domstolsprövning av förvaltningsbeslut enligt svensk, dansk och österrikisk rätt. Framställningen omfattar en rättslig analys av de regler och principer som styr dels när en domstolsprövning av förvaltningsbeslut kan komma till stånd (vilka sakprövningsförutsättningar som gäller), dels vad en sådan prövning omfattar och kan leda till (

Association of Weather with Day-to-Day Incidence of Myocardial Infarction : A SWEDEHEART Nationwide Observational Study

Importance: Whether certain weather conditions modulate the onset of myocardial infarction (MI) is of great interest to clinicians because it could be used to prevent MIs as well as guide allocation of health care resources. Objective: To determine if weather is associated with day-to-day incidence of MI. Design, Setting, and Participants: In this prospective, population-based and nationwide setti