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All hematopoietic cells originate from hematopoietic stem cells (HSCs) residing in the bone marrow (BM). The classical model of hematopoietic lineage commitment, that has been the prevailing model for hematopoiesis, proposes that the first lineage commitment step of HSCs and progenitors results in a strict separation of myelopoiesis and lymphopoiesis. However, an alternative model has already been

Diabetes is a disease characterized by insufficient capacity to regulate the blood glucose level. In insulin-dependent diabetes, multiple daily injections of insulin have to be administered. In-between scheduled visits to the care provider, the patient has to manage the glucose control independently. Insulin dosing is a non-trivial task and many patients find it difficult. This is reflected in the

Popular Abstract in English The dissertation is divided into two parts. The first part deals with the development of a questionnaire diagnostic instrument for atopic dermatitis (AD). The second part concerns following a cohort and assessing the natural history of AD, in which the effect of specified risk factors is analysed. In Värmland, Sweden, a questionnaire that diagnoses AD in infants and preAbstract In childhood atopic dermatitis (AD) is the most frequent inflammatory condition. Validated eczema questionnaires have been available for schoolchildren only, but the incidence of atopic dermatitis is highest during infancy. Evidence is needed on the further development of asthma, and rhinitis in these infants with AD and on remission of AD in children. We aimed to validate a parental ques

Gestational diabetes mellitus (GDM) is associated with a risk of adverse pregnancy outcome and is a predictor of subsequent diabetes. The aims of this work were to describe a reliable routine to diagnose abnormal glucose tolerance during pregnancy, to investigate women’s opinions of the specialist care provided, to determine the prevalence of diabetes one year after giving birth, and to elucidate

Productivity of labour is particularly important especially in developing countries where most of the building work is still carried out on manual basis. Previous research has pointed out that productivity in the building industry is low and in some cases declining. Poor productivity of craftsmen is one of the causes of cost and time overruns on building projects. The objective of this research wa

Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. Following an MI it is important to accurately determine the size of the infarction, as it can be used for guidance in terms of

Seawater desalination constitutes an important water supply to the population bordering the Arabian Gulf, the Mediterranean Sea and the Red Sea. The three regions represent about 11.8% of the world land area and the countrieshosted approximately 9% of the world population in 1950 and 2008 and are also projected to do so in 2050. The results obtained for desalination capacity in the study area were

5 Title: The user involving innovation process in Fuzzy Front End – A case study at Getinge Infection Control Authors: Fredrik Sjölund and Jan Van Helleputte Tutors: Susanna Bill – PhD student, Department of Packaging Logistics, Lund Institute of Technology Fredrik Häglund – PhD student, Department of Business Administration, Lund School of Economics and Management Jerker Funnemark – Pro

Syftet med detta arbete är att redogöra för reglerna kring avveckling av dödsbon i Sverige, d.v.s. reglerna om dödsboförvaltning och arvskifte. Behandlingen inriktar sig framför allt på formerna för förvaltningen – vem som har rätt att företräda dödsboet, hur denna behörighet uppkommer och vad den består i. Fokus ligger på hur dödsbodelägarnas samarbete är reglerat och vilka lösningar lagen erbjud

Allmänt känt hos många jurister – om inte alla – är att allmän domstol använder sig av vissa utarbetade modeller eller metoder då den har att utföra en tolkningsoperation på ett avtal. Dessa metoder underlättar för tolkaren att uppvisa enhetlighet i bedömningen så att lika avtal tolkas lika. Detta är även önskvärt då det leder till ett visst mått av förutsägbarhet. Allmänna reklamationsnämnden är

Ett olovligt bortförande eller kvarhållande föreligger när ett barn under sexton år har blivit bortfört eller kvarhållet i en stat, som inte utgör barnets hemvist, i strid med vårdnadshavarens vilja. 1980 års Haagkonvention, som har införlivats i svensk rätt genom verkställighetslagen (VerkstL), har utarbetats i syfte att skydda de barn som har blivit olovligen bortförda eller kvarhållna mellan la

The treatment for head and neck squamous cell carcinoma (HNSCC) is surgery or (chemo)radiotherapy +/- surgery. Side effects related to therapy are long lasting and adversely affects quality of life. The incidence of oropharyngeal cancer is increasing and patients commonly present an advanced tumour stage with neck metastases at the time of diagnosis. The treatment protocol previously comprised rad