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En konkurrensklausul eller a covenant not to compete, utgör vad man kallar för negativ avtalsförpliktelse och används idag av företag, vilka har ett intresse av hindra att en upparbetad eller förvärvad kunskapsbank om exempelvis avancerad produkt- och metodutveckling; så kallad know how och annan vital information kommer till konkurrerande intressen kännedom. Genom att använda sig av konkurrensklaA non-compete clause or a covenant not to compete, is what is also called a negative contractual obligation. These form of contractual restraints are used by employers and business holders which have an interest in preventing competing interests from getting hold of, by the employer or business holder, established or acquired knowledge about, for example, advanced product and method development; k

Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. However, ovarian cancer is a heterogeneous disease comprising different disease entities, which is of importance in clinical decision-mak

In the blood system, knowledge on the regulation of hematopoietic stem cells (HSCs) and their immature progeny has provided roadmaps of differentiation. Such information can also have a value to understand the etiology of hematological cancers, since clinical heterogeneity and prognostic therapeutic outcomes have been proposed to associate with the specific developmental stage from which the trans

Androgens regulate male reproductive function and their effects are mediated through the androgen receptor (AR). The AR gene contains a polymorphic CAG repeat, encoding a stretch of glutamines, affecting the transcriptional activity of the AR. Prostate specific antigen (PSA) is a downstream target and is commonly used in the screening of prostate cancer. The relationship between CAG number and mal

Geographical accessibility is fundamental when planning rescue services. At present there are several programs for computing the accessibility of stationary rescue units. This study suggests a method for evaluating geographic accessibility in scenarios containing also non-stationary units. The method supports the planning process by matching the risk of an incident occurring with the rescue units’

In this communication, we add another piece of evidence in favor of a parametric split to do with AGR (Holmberg 2010) between Insular (ISc) and Mainland Scandinavian (MSc); the extended possibility of non-subject fronting in embedded clauses, here referred to as Extended verb second (xV2), available in ISc, unavailable in MSc. By adding this phenomenon to the list of AGR-related differences betwee

Objectives: Tetrachloroethylene is the dominant solvent used in dry cleaning worldwide and many workers are potentially exposed. We report here on results of 1296 measurements of tetrachloroethylene undertaken in Nordic dry cleaning shops 1947–2001. Methods: We searched documents and files in the Nordic institutes of occupational health for air measurements of tetrachloroethylene. Repeated measur

In various inflammatory conditions a close interplay between inflammation and coagulation is known to exist, where coagulation factor VII (FVII) and tissue factor (TF) are considered to be pivotal players. In this thesis the crosstalk between inflammation and coagulation in acute pancreatitis (AP) has been investigated. The results from the first paper, where active site inactivated FVII (FVIIai)

Background and objective: General anaesthesia impairs respiratory function. The present studies were performed to compare arterial concentration of sevoflurane, oxygen and carbon dioxide in normal and overweight patients ventilated with increased tidal volume (VT), or normal tidal volume with and without PEEP. Methods: Prospective, randomised, clinical studies. ASA І and II abdominal surgery patie

Abstract Acute kidney injury (AKI) is a common and serious complication after cardiothoracic surgery and is associated with increased short- and long-term mortality risk. Despite extensive studies in the field, a comprehensive understanding of this syndrome has remained elusive, partly due to divergent definitions of AKI and partly due to the limitations of available routine biomarkers to predict,

Doctoral dissertation Abstract Background The relation between mental illness and accountability, may at its best be described as unclear. A negative correlation them between was established thousands of years ago, and has since formed a more or less self-evident supposition. This dissertation is an effort to test this construction. Aims and hypothesis The overall aim of this thesis is to cla