Filetype
Aging of the hematopoietic stem cell compartment is believed to contribute to the onset of a variety of age-dependent blood cell pathophysiologies. Mechanistic drivers of hematopoietic stem cell (HSC) aging include DNA damage accumulation and induction of tumor suppressor pathways that combine to reduce the regenerative capacity of aged HSCs. Such mechanisms do not however account for the change i
Much of the pronounced host inflammatory response that occurs in tuberculosis (TB) is related to failed immunity against the invading pathogen. The G-protein coupled receptors CXCR1 and CXCR2 are implicated in important signal transduction pathways in lung inflammatory responses. We investigated the expression and function of these receptors in a simple whole blood model from 24 patients with pulm
Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells activated by TBI remains poorly defined. Several animal models showing invasion of circulating classical dendritic cells type 2 (cDC2s) to the traumatically in
Acquisition of complement regulators is a virulence strategy used by nontypeable Haemophilus influenzae (NTHi) to evade complement-mediated killing by the host. The major outer membrane protein of NTHi, P5, binds C4b-binding protein and factor H to promote bacterial serum resistance. We show that P5 also binds vitronectin, which inhibits the formation of the membrane attack complex at the terminal
Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity against multidrug, extensive and pandrug-resistant war-wound isolates from Ukraine.Materials and methods: We tested 215 clinical samples (2022-2023) isolated from wounded patients
We have generated two reporter plasmids that either monitor expression of human papillomavirus type 16 (HPV16) E2 mRNAs using splice site SA2709 or HPV16 E1C mRNAs utilizing splice site SA2582. In plasmid pE2sLuc, the entire E2 open reading frame was replaced by the secreted luciferase (sLuc) reporter gene and in the pE1nLuc plasmid the E1/E1C open reading frame was fused in frame with the nanoluc
M A L M Ö A R T — A C A D E M Y — Y E A R B O O K — 2 0 1 2 — 2 0 1 3 2 2 M A L M Ö A R T — A C A D E M Y — Y E A R B O O K — 2 0 1 2 — 2 0 1 3 Foreword Master of fine arts 2 Andreas Albrectsen Una Margrét Árnadóttir Daniel Peder Askeland Martin Berring Johan Eldrot Ingrid Furre Tiril Hasselknippe Martine Sepstrup Jensen Sindri Leifsson David Nilson Maria Norrman Jessica Sanderheim Linda Spjut Mai
https://www.khm.lu.se/sites/khm.lu.se/files/yearbook2013.pdf - 2026-07-23
Toxin-antitoxin-chaperone (TAC) systems are three-part gene clusters encoding a toxin, antitoxin, and specialized SecB-like chaperone (SecB TA) with emerging roles in phage defense. To identify and classify SecB homologs and associated TACs across bacteria, we surveyed the full RefSeq database. Phylogenetic and gene neighborhood analyses reveal three major SecB subfamilies: two housekeeping group
UNLABELLED: Pectobacterium brasiliense ( Pbr) is known to be one of the most virulent Pectobacterium species and is generally widely distributed across the globe, especially known for causing soft rot in potato-tubers and black leg in potato-plants. Currently no treatment mechanism exists, and many studies have focused on alternative treatment approaches such as biocontrol agents. Several stu
Sammanfattning Kapitel 2 Presentation av ett nytt tumör-behandlingskoncept med ”Pre-kirurgisk intermittent ultrahypofraktionerad strålbehandling” (PSiRT) ”kombinerad med immunterapi” (PSiRIT), särskilt immun¬kontrollpunktshämmare (anti-CTLA4 och anti-PD-1).Intermittent ultrahypofraktionerad strålbehandling innebär:• Optimal absorberad dos 6–8 Gy per fraktion • Doser >10 Gy kan öka immunosuppress
Abstract – Background: Cytological examination of a fine-needle aspirate (FNA) is a minimally invasive modality that is increasingly used in the diagnosis of lymphoma. Flow cytometry and other ancillary tests make an important contribution to the diagnostic value of FNAs of lymphoid lesions. This review follows the recent publication of the first edition of the WHO Reporting System for Lymph Node,
PURPOSE: To determine whether Comprehensive Geriatric Assessment (CGA)-based healthcare, delivered by a mobile team over 24 months in patients' homes reduces hospital care or improves quality of life, physical performance, frailty, activities of daily living (ADL), or cognition and whether it reduces mortality or number of hospital admissions.METHODS: Patients ≥ 75 years of age, with ≥ 3 visits to
Time-dependent diffusion MRI enables the estimation of water exchange rates in vivo. Most studies attribute these estimates to membrane permeability. However, non-permeative geometric exchange may also contribute. The present study investigates the contribution of geometric exchange between dendritic spines and shafts to diffusion MRI-derived exchange estimates. Monte Carlo simulations were perfor
Twenty-four strains of Mobiluncus mulieris and 27 strains of Mobiluncus curtisii were tested with respect to 6 different biochemical characteristics: arginin-decarboxylase activity, beta-galactosidase activity, synergistic hemolysis with Staphylococcus aureus, hydrolysis of hippurate, migration through soft agar and reduction of nitrate. Antigens of the same strains, prepared by ultrasonication, w
Drop-in för dig som skriver exjobb Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i
https://www.lth.se/bibliotek/article/drop-in-foer-dig-som-skriver-exjobb/ - 2026-07-23
statisticalconsulting | Matematikcentrum Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i våra system. Dessa
https://www.maths.lu.se/statisticalconsulting/ - 2026-07-23
8_2_20231207_LTHPedKonf_MottePugh_Edges_vf_mod LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Abstract—When a course is designed, it is common to do it for a typical group of students, considered to represent “the majority”, the “norm” or the “average”. The concept of “edges” challenges this view: given the multiple dimensions that teaching and learning encompass, there will always
https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/D1b_Motte_Pugh.pdf - 2026-06-09
About CEE | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store
https://www.lth.se/english/cee/about-cee/ - 2026-06-09
