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This thesis has evaluated the immunological- and epidemiological aspects of human papillomavirus transmission dynamics and its effect on circumcision. Effective prophylactic vaccines are based on type-specific neutralizing antibodies. A major neutralizing epitope is defined by the monoclonal antibody H16.V5. To investigate the importance of this epitope for overall immunogenicity of HPV16, we en
Abstract in UndeterminedUzbekistan, after gaining independence from the Soviet Union in 1991, had publicly declared that it would adhere to democratic governance principles in designing and implementing its public administration policies. As a newly-independent state with democracy claims, Uzbekistan had tried to establish new democratic institutions with an effort to capture international communi
Estimates of relevant source area of pollen (RSAP) and relative pollen productivity (PPE) are critical parameters for quantitative reconstructions of past vegetation and land cover. This study provides estimates for PPE relative to Poaceae for ten taxa, characterizing the cultural landscape of south Estonia and the RSAP for 40 lakes with an average radius of approximately 100 m (22-274 m, average
This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. However, it is unclear whether the associations with several types of cancers are due to share
1. A new methodological approach for detailed study of the organization of the cerebellar corticonuclear projection was evaluated in barbiturate-anaesthetized cats. Extracellular field potentials were simultaneously recorded in nucleus interpositus anterior and in the forelimb area of the C3 zone, at the cerebellar surface. On electrical and natural stimulation of the forelimb skin, the evoked pos
Material contributes to a large share of construction costs and as prices are increasing companies must seek creative solutions and find new approaches in order to find ways of saving money. As a part of a strategic development Peab, one of Sweden’s leading construction- and contractor companies, is making an effort to streamline their purchasing system using the purchasing tool PIA, which digital
During an archaeological excavation in Uppåkra 2010 I found a so-called “guldgubbe”(goldfoilfigure). This find really caught my attention and especially so because their functions are still debated. This master thesis is about the meaning and use of this, more appropriately called, goldfoilfigure. Many attempts to solve the questions surrounding the functions of the figures have been made during t
Uppsatsens huvudsakliga syfte är att utreda om det med härledning till EU-rätten och EUD:s rättspraxis kan utrönas en gränsdragning för när en privatperson till-handahåller tjänster kan anses göra detta i egenskap av en beskattningsbar person och följaktligen faller transaktionen under mervärdesskatterättens tillämpnings-område. Utredningens analytiska utgångspunkt utgår från det ekonomiska sam-liThis essay's main purpose is to examine when a private individual, who provides services, can be considered to do this as a taxable person and therefore falls under the scope of VAT. This survey's analytical starting point is based on the economic concept collaborative consumption. The term describes an economic model which is based on the coordination of individuals' consumption needs
55 m.ö.h. på Balsbergets södra sluttning finner man en av Sydsveriges största grottor, Balsbergsgrottan. Ungefär 250 meter vindlande gångar grenar sig ut från två större salar. Grottan har en rik historia, både ur ett geologiskt och ett funktionalistiskt perspektiv. De sedimentära bergarterna som bildades för 100 miljoner års sedan lade grunden till, att det efter förra istiden kunde bildas en gro55 meters above sea level on the southern slope of Balsberget you can find one of southern Sweden's largest caves, the Balsberg cave. Approximately 250 meters winding paths branch out from two large halls. The cave has a rich history, both from a geological and a functional perspective. The sedimentary rocks, formed 100 million years ago, laid the foundations for the advent of a cave here afte
Klimatförändringar har amplifierats sedan den industriella revolutionen och modeller pekar på att förändringen kommer forsätta att öka åtminstone till slutet av detta århundrande. Globala temperaturer och nederbörd förväntas öka avsevärt under detta århundrade. Dessa ökningar förväntas bli särskilt markanta i de arktiska områdena. Torvmyrar belägna på höga latituder vid 0ºC isothermen, såsom StorfThe rate of change of our climate has been amplified since the industrial revolution and is expected to change even further by the end of this century. Global temperature and precipitation are expected to increase considerably over the next century. These increases are expected to be magnified in the Arctic regions. In a high latitude peatland like Storflaket, near Abisko (Northern Sweden), at the
Flyktiga organiska föreningar som släpps ut från växter (BVOC- Biogenic volatile organic compounds) kan ha en stor påverkan på atmosfärisk kemi genom reaktioner som leder till ökad eller minskad ozonproduktion, och genom att de kan vara ett förstadium till aerosoler. De vanligaste flyktiga organiska föreningarna är isopren (2-metyl, 1,3-butadien) och dess derivat, terpener och terpenoider (isoprenBiogenic volatile organic compounds (BVOCs) can have a large affect on atmospheric chemistry by the production or degradation of ozone and by acting as precursors to secondary organic aerosols (SOA). The most common BVOCs are isoprene and its derivatives, terpenes and terpenoids (isoprenoids). These are used by the plant in cell membranes and as steroids, but are also a means of communication and
The granite massif in the Tjärnesjö area, southwestern Sweden, was deformed and metamorphosed under granulite facies conditions in late Sveconorwegian time. The intrusive is dominated by a coarse-grained, megacrystic orthoclase granite. Pb-Pb evaporation datings on single zircons from the granite yield an age of ca. 1.36 Ga, interpreted as the intrusion age. A similar age was obtained on zircons f
Problem Statement After the hurricane Gudrun in January 2005 EON Elnät Sverige AB started the project KRAFTTAG, were 17,000 km of the airborne power grid shall be replaced with cables underground. The transformers in the airborne power grid shall be dismounted, renovated if necessary and then conveyed to stations, of type kiosk. Additional new transformers, more than planned, have been bought. T
Background: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. Avian MHC organization is of particular interest because the chicken Gallus gallus, the avian species with the best characterized MHC, possesses a highly streamlined minimal essential MHC, which is linked to resis
Wilms' tumor 1 antigen (WT1) is overexpressed in acute myeloid leukemia (AML), a high-risk neoplasm warranting development of novel immunotherapeutic approaches. Unfortunately, clinical immunotherapeutic use of WT1 peptides against AML has been inconclusive. With the rationale of stimulating multiantigenic responses against WT1, we genetically programmed long-lasting dendritic cells capable of pro
Non-melanoma skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. We extended the heterogeneity of the genus Betapapillomavirus by characterizing six putative types, HPV93 (species 1), 96
Rationale and Objectives: To compare the ability of normalized versus non-normalized metabolite ratios to differentiate recurrent brain tumor from radiation injury using magnetic resonance spectroscopy (MRS) in previously treated patients. Materials and Methods: Twenty-five patients with previous diagnosis of primary intracranial neoplasm confirmed with biopsy/resection, previously treated with ra
Background: Infection is a serious adverse effect of prostate biopsy (P-Bx), and recent reports suggest an increasing incidence. Objective: The aim of this multinational multicentre study was to evaluate prospectively the incidence of infective complications after P-Bx and identify risk factors. Design, setting, and participants: The study was performed as an adjunct to the Global Prevalence Study
The biodegradability of dissolved organic carbon (DOC) in different fractions from the forest floor was studied. Soil leachate (SI, the soil solution in macropores which is freely drained from forest floor after rainfall), the soil matrix solution (SMS, the soil solution in meso-/micropores of the soil matrix), and soil water extracts (SWE) from two different beech forest floors were compared. Zer
