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Objectives: To explore associations between carer burden and characteristics of (1) the informal carer, (2) the person with dementia, and (3) the care support network in 8 European countries. Design: Cross-sectional study. Setting: People with dementia judged at risk of admission to long-term care (LTC) facilities in 8 European countries (Estonia, Finland, France, Germany, Netherlands, Spain, Swed
AbstractBackgroundThere is a need for easily administered objective tests in neurodevelopmental disorders. We investigated the clinical utility for child and adolescent psychiatry of Auditory Brainstem Response (ABR) and Cambridge Neuropsychological Test Automated Battery (CANTAB) as support in diagnosing attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). MethodsTh
microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. A single miRNA can target hundreds of genes and one gene can be targeted by several miRNAs, hereby giving rise to a complex post-transcriptional network. In the brain, hundreds of miRNAs are expressed
Aims/hypothesis: During the A/H1N1 2009 (A/California/04/2009) pandemic, mass vaccination with a squalene-containing vaccine, Pandemrix®, was performed in Sweden and Finland. The vaccination was found to cause narcolepsy in children and young adults with the HLA-DQ 6.2 haplotype. The aim of this study was to investigate if exposure to Pandemrix® similarly increased the risk of islet autoimmunity o
BACKGROUND AND PURPOSE: Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arterial stiffness, cerebral microbleeds, and vascular events. The aim of this study was to investigate the association of circulating levels of TNFR1 and TNFR2 with risk for future intracerebral hemorrhage (ICH).METHODS: The population-based MDCS cohort (Malmö Diet and Cancer Study;
Genetic factors are important in the pathogenesis of osteoporosis and the estrogen receptor has been suggested as a possible candidate gene for regulation of bone mineral density (BMD). We investigated the relationship between PvuII, XbaI, and dinucleotide (TA)n repeat polymorphisms of the estrogen receptor alpha (ER-alpha) gene and BMD in a study of women from northeast Scotland in the United Kin
BackgroundThe Scandinavian Neurotrauma Committee (SNC) has recommended the use of serum S100B as a biomarker for mild low-risk Traumatic brain injuries (TBI). This study aimed to assess the adherence to the SNC guidelines in clinical practice and the diagnostic performance of S100B in patients with TBI. The aims of this study were to examine adherence to the SNC guideline and the diagnostic accura
Background: A comprehensive assessment of morbidity after allogeneic bone marrow transplantation (BMT) performed in childhood remains understudied. Methods: Seven hundred eighty-nine allogeneic BMT recipients who had survived ≥2 years after BMT performed between 1974 and 2014 at age <22 years and 690 siblings completed a 255-item survey self-reporting sociodemographics and chronic health condition
Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects. Objective: To explore candidate biomarkers of synaptic dysfunction
Tourism enterprises play a vital role in tourism development. This has inspired scholarly and policy interest in the workings of tourism enterprises, particularly the small enterprises that account for the majority. The heterogeneity of small enterprises presents challenging terrain for scholars and policymakers concerned to understand and manage enterprise development and tourism development. Sch
BACKGROUND: The St Gallen 2019 guidelines for primary therapy of early breast cancer recommend omission of completion axillary lymph node dissection (cALND), regardless of histological type, in patients with one or two sentinel lymph node (SLN) metastases. Concurrently, adjuvant chemotherapy is endorsed for luminal A-like disease with four or more axillary lymph node (ALN) metastases. The aim of t
Summary: This narrative review describes efforts to improve the care and prevention of fragility fractures in New Zealand from 2012 to 2022. This includes development of clinical standards and registries to benchmark provision of care, and public awareness campaigns to promote a life-course approach to bone health. Purpose: This review describes the development and implementation of a systematic a
Identification of subjects with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention of the disease. Consequently, it is essential to search for new biomarkers that can improve the prediction of T2D. The aim of this study was to examine whether 5 DNA methylation loci in blood DNA (ABCG1, PHOSPHO1, SOCS3, SREBF1, and TXNIP), recently reported to be associated with T2D, migh
Microsoft Word - Sjdlvvdrdering humanekologi Lund _3_.doc 1 GRUND- OCH FORSKARUTBILDNINGEN I HUMANEKOLOGI VID LUNDS UNIVERSITET En självvärdering HUMANEKOLOGISKA RAPPORTER 2 Humanekologiska avdelningen, Lunds universitet 158 HUMANEKOLOGISKA RAPPORTER 2 HUMANEKOLOGISKA RAPPORTER är en serie skrifter utgivna av Humanekologiska avdelningen vid Lunds universitet. Skrifterna utkommer med oregelbundna i
https://www.keg.lu.se/sites/keg.lu.se/files/sjalvvardering_06.pdf - 2026-07-09
Material traceability is an important part of industrial manufacturing, especially in systems where quality, reliability, and documentation requirements are high. In many companies, traceability is often assumed to already exist because there are certificates, ERP systems, production documents, and established routines. However, during this study, it became clear that having information available
This thesis investigates how existing urban environments can be adapted to strengthen climate resilience and improve everyday access to urban rest within dense cities. Urban rest is understood as restorative conditions within the everyday urban environment, where opportunities for pause, recovery, and social interaction can occur across both public and semi-private spaces. The thesis identifies an
Purpose: The study aimed to investigate the associations between impaired spirometry such as obstructive pattern and preserved ratio impaired spirometry (PRISm) and occurrent cardiovascular events and deaths in patients with acute myocardial infarction. Patients and Methods: Cohort study of 517 patients with age ≥40 years and ≥10 pack-years of smoking, hospitalized for myocardial infarction at eig
This thesis examines how Swedish legal and administrative frameworks governing LKAB’s mining operations have historically produced and reproduced the invisibility of Sámi land use, and how these patterns of exclusion continue to be mobilized within contemporary green transition justifications. Drawing on settler colonial theory and anopticism, the study argues that Sámi exclusion within Swedish re
