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The COVID-19 accelerated shift towards hybrid workspaces places major pressure onworkplace communities and culture. This study explores the emergence of a collaborative academic workspace, which is still in the real estate development phase. The aim is to establish preconditions for community building, and the relationship between the community and the physical space. The study employs a qualitati
Predation risk is often invoked to explain variation in stress responses. Yet, the answers to several key questions remain elusive, including the following: (1) how predation risk influences the evolution of stress phenotypes, (2) the relative importance of environmental versus genetic factors in stress reactivity and (3) sexual dimorphism in stress physiology. To address these questions, we explo
OBJECTIVE: The aim of the present study was to examine the effects of incomplete surgery and adjuvant chemotherapy on the prognosis of patients with intraoperative rupture of capsulated stage I epithelial ovarian cancer (OvCa). METHODS: A regional retrospective study was conducted between 1986 and 2019. Among 4,730 patients with malignant ovarian tumors, 534 women with International Federation of
Objectives: The aim of this study was to evaluate the short-term safety and efficacy of transcatheter aortic valve replacement (TAVR) with the LOTUS Edge system. Background: The LOTUS Edge system was commercially re-released in April 2019. The authors report the first European experience with this device. Methods: A multicenter, single-arm, retrospective registry was initiated to evaluate short-te
Background: Transrectal prostate biopsy (TRbx) transfers colonic bacteria into prostatic tissue, potentially causing infectious complications, including sepsis. Our objective was to determine whether biopsy needle shape, surface properties and sampling mechanism affect the number of bacteria transferred through the colon wall, and evaluate a novel needle with improved properties. Methods: The stan
Cerebellar dysfunction after traumatic brain injury (TBI) is commonly suspected based on clinical symptoms, although cerebellar pathology has rarely been investigated. To address the hypothesis that the cerebellar axon-myelin unit is altered by diffuse TBI, we used the central fluid percussion injury (cFPI) model in adult mice to create widespread axonal injury by delivering the impact to the fore
Winter warming events (WWE) are abrupt and short-lasting (hours-to-days) events of extraordinarily warm weather occurring during wintertime, sometimes accompanied by rainfall (rain on snow events; ROS). Through direct heat transfer and changes in the snowpack properties, these events cause changes in the below-ground thermal regime that, in turn, controls a suite of ecosystem processes ranging fro
Aims/hypothesis: Genome-wide association studies (GWAS) have identified more than 65 genetic loci associated with risk of type 2 diabetes. However, the contribution of distorted parental transmission of alleles to risk of type 2 diabetes has been mostly unexplored. Our goal was therefore to search for parent-of-origin effects (POE) among type 2 diabetes loci in families. Methods: Families from the
Cancer is one of the leading causes of death worldwide, but reliable diagnosis and staging can contribute to optimal treatment planning, and is a crucial factor in reducing mortality and maintaining quality of life. Soft tissue mechanical properties are promising indicators of cancer that can be assessed non-invasively using functional imaging. Additionally, lymphatic involvement is considered a k
Respiration in animals, plants and many bacteria is dependent on heme A, which functions as a prosthetic group in a-type cytochromes (terminal energy-transducing oxidases in the electron transport chain that reduce molecular oxygen to water). Heme A synthase catalyses a chemically very demanding reaction, the conversion of one specific methyl side-group of heme O to a formyl group of heme A. This
Every year about 15 million people are injured in traffic, 500,000 of these fatally. Developing countries are badly affected. During the worst years of the war in Nicaragua, more people died in traffic accidents than as a direct result of the war. Transport system and infrastructure have developed rapidly in developing countries, while little has been achieved in preventing accidents or lessening
Keynote paper The point of departure for this lecture lies in the insight that tourism research is uniquely positioned at the juncture of applied and scholarly research. Drawing upon work I have conducted in the realms tourism and leisure study, the lecture strives to problematize the practice of ethnography as a method and raise questions concerning the opportunity research in the fields of tour
