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We evaluated the relation between serum FGF23 and bone mineral density (BMD) in a community-based cohort of elderly men. There was a weak correlation between FGF23 and BMD, which was primarily dependent on body weight. FGF23 is a hormonal factor produced in bone and regulates serum levels of phosphate (Pi) and vitamin D. FGF23 over-expression is associated with skeletal abnormalities, including ri
Weathering of soil minerals is important for the recovery from acidification and for the sustainability of forestry. However, there is still substantial uncertainty about its absolute rate. This study presents a harmonized comparison of field weathering rates estimated with the mechanistic model PROFILE and the depletion method for 16 intensively sampled soil profiles across Sweden representing di
The widespread use of artificial nestboxes has led to significant advances in our knowledge of the ecology, behaviour and physiology of cavity nesting birds, especially small passerines Nestboxes have made it easier to perform routine monitoring and experimental manipulation of eggs or nestlings, and also repeatedly to capture, identify and manipulate the parents However, when comparing results ac
Background: Colon capsule endoscopy (CCE) represents a noninvasive technology that allows visualization of the colon without requiring sedation and air insufflation. A second-generation colon capsule endoscopy system (PillCam Colon 2) (CCE-2) was developed to increase sensitivity for colorectal polyp detection compared with the first-generation system. Objective: To assess the feasibility, accurac
Aims: We assessed whether a novel programme to evaluate/communicate predicted coronary heart disease (CHD) risk could lower patients' predicted Framingham CHD risk vs. usual care. Methods: The Risk Evaluation and Communication Health Outcomes and Utilization Trial was a prospective, controlled, cluster-randomised trial in nine European countries, among patients at moderate cardiovascular risk. Fol
Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab 302: E950-E960, 2012. First published January 31, 2012; doi:10.1152/ajpendo.00466.2011.-Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. Howe
Popular Abstract in English Every year globally, an estimated 1.7 million women are diagnosed with breast cancer, while over half a million are killed by this disease. The principal cause of death is metastasis, which is the spreading of the cancer cells from the breast to other vital organs like the brain, liver or lungs, resulting in organ failure and subsequently death. Even though the past decMetastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu
In this study, field experiments and numerical simulations for different drip irrigation treatments in a sandy loam soil were conducted to investigate soil water and salinity distribution as well as dye infiltration patterns. Three treatments, surface drip irrigation without and with plastic mulch (T1 and T2, respectively); and subsurface drip irrigation (T3), were used. In addition, daily and bi-
Background: Covered biliary metal stents have been developed to prevent tumor ingrowth. Previous comparative studies are limited and often include few patients. Objective: To compare differences in stent patency, patient survival, and complication rates between covered and uncovered nitinol stents in patients with malignant biliary obstruction. Design: Randomized, multicenter trial conducted betwe
Streptococcus pyogenes is an important human pathogen and surface structures allow it to adhere to, colonize and invade the human host. Proteins containing leucine rich repeats (LRR) have been indentified in mammals, viruses, archaea and several bacterial species. The LRRs are often involved in protein-protein interaction, are typically 20-30 amino acids long and the defining feature of the LRR mo
The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. Vasculitis is an autoimmune systemic inflammatory disease, characterized by leukocyte inflammation in and around vessel wall
In our everyday life we live distant from the origin of life itself - nature. Dramatic landscape and fascinating views touch us in a way that few other things manage to do. It is something that make us recognize our powerlessness and the feeling of awe towards the nature. Experiencing striking nature is a way to create a deeper understanding of our own world and at the same time enrich our lives w
We are daily moving in different landscapes for various reasons; sometimes we are looking for specific activities and sometimes just to move from one place to another. Common for this is the affect the landscape can have on us and how it gives us different experiences. In this essay I seek answers to what is important for people when they visit the nature for recreational purposes. What factors do
Syftet med denna studie är att undersöka om körsång kan användas som ett verktyg för att motverka psykisk ohälsa bland ungdomar genom elevhälsan. Vidare undersöktes även huruvida körpedagoger ser fördelar med att beakta körsångens hälsoeffekter i sin egen undervisning, och hur möjligheten för att använda körsång inom elevhälsan i dagens gymnasieskola ser ut. För att genomföra studien gjordes tre kThe purpose of this study is to investigate if choir singing can be used as a tool to prohibit mental illness or bad mental health amongst youths through student health services. The study also investigates if choir teachers can see benefits of teaching choir with choir singings health effects in mind, and what the possibility is to use choir singing as a tool in today’s high schools (Swedish gymn
År 2019 besökte 1,9 miljoner personer i åldrarna 19 år eller äldre akutmottagningarna i Sverige. Vistelsetiderna på akutmottagningarna ses samtidigt i stora delar av landet öka. Patientflöde och arbetsbelastning är ständigt i förändring och de senaste åren har vårdplatsläget orsakat stora bekymmer med kvarstannande patienter, så kallad crowding. Tidigare forskning visar att sjuksköterskor ofta bliDuring 2019 the emergency departments in Sweden had 1.9 million visitors aged 19 years or older seeking medical assistance. Throughout the majority of Sweden the time spent at the emergency departments is increasing according to the National Board of Health and Welfare (Socialstyrelsen, 2020). Several factors influence the work performed by registered nurses at an emergency department. The flow o
