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Background We aimed to estimate lifetime cumulative risk of thyroid cancer (CRTC) in first-degree relatives of patients with non-medullary thyroid cancers (NMTC), including papillary (PTC)/follicular/oxyphilic/anaplastic thyroid carcinoma, by histology and age at diagnosis in patients and their relatives. Design A population-based cohort of 63 495 first-degree relatives of 11 206 NMTC patients dia

It is expected that, in the future, gas turbines will be operated on gaseous fuels currently unutilized. The ability to predict the range of feasible fuels, and the extent to which existing turbines must be modified to accommodate these fuels, rests on the nature of these fuels in the combustion environment. Understanding the combustion behavior is aided by investigation of syngases of similar com

Popular Abstract in Swedish De två vanligaste typerna av neurodegenerativ demenssjukdom är Alzheimer’s sjukdom och Lewy body demens. Båda sjukdomarna drabbar framförallt äldre människor och risken att insjukna ökar med stigande ålder. Detta innebär att demenssjukdom kommer att bli vanligare i samhället, eftersom vi blir allt äldre och andelen invånare >65 år blir allt större. Att drabbas av demensBackground: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. Aim: The aim of this thesis is to identify, review and qualif

Diagnosis and risk stratification of patients with acute coronary syndromes can be improved by adding information from the depolarization phase (QRS complex) to the conventionally used ST-T segment changes. In this study, ischemia-induced changes in the main three slopes of the QRS complex, upward (I-US) and downward (I-DS) slopes of the R wave as well as the upward (I-TS) slope of the terminal S

Background: This population-based study investigated the different forms, magnitude and risk factors of men's violence against women in intimate relationships in a rural part of northern Vietnam and whether a difference in risk factors were at hand for the different forms of violence. Vietnam has undergone a rapid transition in the last 20 years, moving towards a more equal situation for men and w

Background: Exposure to ambient air particulate matter (PM) has been linked to decline in pulmonary function and cardiovascular events possibly through inflammation. Little is known about individual exposure to ultrafine particles (UFP) inside and outside modern homes and associated health-related effects. Methods: Associations between vascular and lung function, inflammation markers and exposure

Nager A, Szulkin R, Johansson S-E, Johansson L-M, Sundquist K. High lifelong relapse rate of psychiatric disorders among women with postpartum psychosis. Nord J Psychiatry 2013;67:53-58. Background: The relapse rate for psychiatric disorders after postpartum psychosis is high. Apart from subsequent puerperal periods, previous studies have not examined when relapses in psychiatric disorders occur.

Abstract Objective. To study the associations between active choice of primary care provider and healthcare utilization, multimorbidity, age, and sex, comparing data from primary care and all healthcare in a Swedish population. Design. Descriptive cross-sectional study using descriptive analyses including t-test, correlations, and logistic regression modelling in four separate models. Setting and

Popular Abstract in Swedish Svenska Pommerns historia är en del av den svenska historien. Mellan 1648 och 1815 hörde den tyska Östersjöprovinsen till det svenska väldet. Denna avhandling skildrar människorna och deras syn på Sverige under de sista hundra åren av svensk tillhörighet mellan 1720 och 1815. Hur påverkades provinsens invånare av att å ena sidan räkna sig till den tyska kulturen och å aBetween 1648 and 1815, Swedish-Pomerania, at the Baltic shore, belonged to the crown of Sweden. It was both a part of the Holy Roman Empire of German Nation and the Swedish realm. The port town of Stralsund played a key roll in the Swedish economy at the Baltic Sea, whereas the university town of Greifswald was the intellectual centre. On a cultural level, this situation opened up for a double ins

Popular Abstract in Swedish Avhandlingen handlar om naturföreställningar i resereklam och bland re-senärer. Syftet var att analysera hur natur framställs i reklambilder för resor, vad reklamens framställning av natur har för betydelse för vad resenärer vill uppleva och upplever i samband med sin resa samt med vilka argument och bilder resenären själv väljer att återskapa upplevelserna av sin resa It is commonly believed that we live in a culture that is increasingly permeated by visual images. One category of images that we encounter everyday in different media, and that constitutes a large and growing part of media content, is advertisements. Advertisements also have a specific purpose and the images represent, make meaning of, and convey sentiments about phenomena. In this dissertation,

For people with learning disabilities care in institutions has been replaced by a life in community settings e.g. group homes, where a number of persons (4-5) are living with staff support. My case-studies cover three elderly and three more lately produced such units as well as a ward in a nursing home. Data were gathered through participant observations and semistructured interviews with staff an

Background: The survival for patients with atrioventricular septal defect has improved markedly over the last decades and, during the same period, the survival of children with Down's syndrome has also increased. The aim of our study was to investigate long-term survival in patients having atrioventricular septal defect with common valvar orifice, but without associated significant congenital hear

The first paper, Pharmaceutical R&D: a real option approach, considers the process of pharmaceutical R&D analyzed with real option theory. This process is analyzed as an opportunity to research and develop a new pharmaceutical. Contrary to other models using real option analysis I use an option that takes time to exercise. Thus, the important aspect of long R&D processes when developin

BACKGROUND: An increasing incidence of penicillin-resistant Streptococcus pneumoniae (PRP) was detected in Malmo in 1994. OBJECTIVE: To evaluate clonality and factors facilitating the spread of PRP among children in day-care centers (DCCs). METHODS: We used phenotypic and DNA-fingerprinting methods in conjunction with epidemiologic data from the South Swedish Pneumococcal Intervention Project's in

Pure cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) in micrograms quantities was isolated from bovine aortic smooth muscle after more than 5000-fold purification using DEAE ion-exchange and affinity chromatography with a derivative of the specific cGI-PDE inhibitor cilostamide conjugated as a ligand to aminoethyl agarose (CIT-agarose). The cGI-PDE, which constituted about half of the high affinit

Hofmeister MV, Damkier HH, Christensen BM, Olde B, Leeb-Lundberg LM, Fenton RA, Praetorius HA, Praetorius J. 17 beta-Estradiol induces nongenomic effects in renal intercalated cells through G protein-coupled estrogen receptor 1. Am J Physiol Renal Physiol 302: F358-F368, 2012. First published October 12, 2011; doi: 10.1152/ajprenal.00343.2011.-Steroid hormones such as 17 beta-estradiol (E2) are kn

PIP: The first generation high-dose ( 80 mcg estrogen) oral contraceptives (OCs) were associated with an increased risk of deep venous thrombosis (DVT). So manufacturers removed the high-dose OCs and first replaced them with OCs with 50 mcg estrogen, resulting in a lower incidence of thromboembolic events (40 vs. 20/100,000 users). When they introduced an even lower dose OC (30 mcg estrogen), the

Prospective cohort studies about cutaneous melanoma (CM) risk are still few. Host factor- and UVR exposure data were collected prospectively by questionnaire in this population-based cohort study including 40000 Swedish born women, aged 25-64 years at enrolment (1990). Risk for CM (Cox regression and Stepwise Cox regression [SCR], hazard ratios [HRs] with 95 % Confidence Intervals [CI]) in relatio