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Knowledge about the natural history of severe alpha 1-antitrypsin (AAT) deficiency (PiZZ) is limited. Our aim was to compare the survival of PiZZ individuals with randomly selected controls from the Swedish general population. The PiZZ subjects (n=1585) were selected from the Swedish National AATD Register. The controls (n=5999) were randomly selected from the Swedish population register. Smoking

Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen

Only three days after the beginning of the nuclear catastrophe in Fukushima, Japan, on 11 March 2011, the German government ordered 8 of the country's 17 existing nuclear power plants (NPPs) to stop operating within a few days. In summer 2011 the government put forward a law - passed in parliament by a large majority - that calls for a complete nuclear phase-out by the end of 2022. These governmen

Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative

The electroweak production and subsequent decay of single top quarks in the t-channel is determined by the properties of the Wtb vertex, which can be described by the complex parameters of an effective Lagrangian. An analysis of a triple-differential decay rate in t-channel production is used to simultaneously determine five generalised helicity fractions and phases, as well as the polarisation of

The aim of this project is to explore and understand the combustion phenomenon in engines operating on gaseous fuels, and develop technologies as an alternative to the present diesel engine technologies for heavy duty applications; which are facing severe challenges like stringent emissions norms, high technology costs and unsustainable fuel supply. The studies presented in this thesis focus on th

OBJECTIVE: To investigate effects of lipid lowering drug, simvastatin, on apolipoprotein M expression in the hyperlipidemic mice and in hepatic cell line, HepG2 cells. METHODS: Swiss male mice were randomly divided into the high fat group and control group, and were intragastrically fed with 0.9% saline (control group) or lipid emulsion (high fat group) at the daily dosage of 15 ml/kg body weight

Poly(styrene-graft-ethylene oxide), having alkyl chains (C-12 or C-18) on the polystyrene main chain or on the poly(ethylene oxide) (PEO) side chains, were synthesized. The main chain was alkylated by first ionizing amide groups in a styrene/acrylamide copolymer with tert-butoxide, and then using the amide anions as sites for reactions with 1-bromoalkanes. An excess of amide anions was used in the

Popular Abstract in Swedish Idag behöver människor som talar, tänker och lever på olika sätt mer än någonsin kunna kommunicera med varandra. Ett självklart språk för dessa kontakter är för en svensk ofta engelska. Det lär sig varje elev under minst tio år i vår skola. Men för att kunna förstå andra bättre, fordras också att vi blir medvetna om skilda sätt att uppfatta världen omkring oss. Vi behövThe aim of this study is to examine the prospects of developing intercultural understanding through English as a foreign language (EFL) education in the Swedish comprehensive school. This overall aim is split into two subordinate aims: (1) to analyse and problematize the intercultural dimension of EFL as three discourses, research discourse, authority discourse and teacher discourse; (2) to relate

Popular Abstract in Swedish I samband med 1990 års skattereform förändrades den allmänna inkomstskatten i grunden. Bl.a. infördes skilda skatteskalor för arbetsinkomster och kapitalinkomster. Inkomster som genereras av arbete beskattas progressivt med 45-75 % men avkastning av kapital proportionellt med 30 %. Allokering av inkomst till respektive inkomstkategori har därför stor betydelse i skattesSince the tax reform of 1990 the Swedish tax system separates earned income and capital income. On earned income such as "income from business" taxes and fees leads to a total margin tax burden that vary between 45 and 75 %. This margin effect can be compared to the 30 % proportional income tax on capital income. The allocation of income to earned income or capital income is therefore an important

I avhandlingen studeras migration i form av anhöriginvandring till Sverige. I fokus ställs parförhållande där parets seriositet prövas av Migrationsverket. Parets väg genom ansökningsprocessen beskrivs liksom den legala ramen kring anhöriginvandring. Vidare tar avhandlingen upp handläggning av anhöriginvandring och vilka föreställningar om anhöriginvandring och seriösa parförhållanden som finns, d

Background: Lumbar spine radiography has limited diagnostic value but low radiation dose compared with computed tomography (CT). The average effective radiation dose from lumbar spine radiography is about 1.1 mSv. Low-dose lumbar spine CT may be an alternative to increase the diagnostic value at low radiation dose, around 1 mSv. Purpose: To determine the optimal settings for low-dose lumbar spine

The aim of this study was to investigate how patients perceive information and their health-related quality of life 1 month after discharge for colorectal cancer surgery. The aim was also to compare these results with the first 2 weeks at home and to identify factors related to the perception of information. One hundred patients from three surgical clinics in the south of Sweden were included in t

This work presents a review of studies on the process economics of ethanol production from lignocellulosic materials published since 1996. Our objective was to identify the most costly process steps and the impact of various parameters on the fi- nal production cost, e.g. plant capacity, raw material cost, and overall product yield, as well as process configuration. The variation in estimated etha

Apolipoprotein M (apoM) is a novel apolipoprotein presented mostly in high-density lipoprotein (HDL) in human plasma. Previously we have reported that both leptin and leptin receptor are essential for apoM expression in vivo. The expression of apoM is lower in the leptin deficient (ob/ob) mouse and leptin receptor deficient (db/db) mouse than in the normal mouse. In the present study, however, we

Popular Abstract in Swedish En autonom agent kan definieras som ett system som med syfte att utföra uppgifter kan interagera med sin omgivning genom sina egna sensorer och effektorer. En ny arkitektur för autonoma agenter inspirerad av teorin för antecipatoriska system föreslås. Det är en hybrid arkitektur i det avseende att den kombinerar planerande förmåga, som behövs för att lösa långsiktiga prThis thesis has two main themes, autonomous agents and concepts. An autonomous agent is a system capable of interacting with its environment via its own sensors and effectors in order to accomplish some task. Arguments against both purely reactive and purely deliberative agent architectures are presented in favor for hybrid approaches. A novel hybrid approach based on the concept of anticipatory s

Popular Abstract in Swedish I den här avhandlingen studeras de elektriska egenskaperna hos nanotrådar av halvledarmaterial. En halvledare är ett mellanting av en ledare och en isolator, där den elektriska ledningsförmågan kan styras både genom att förorena materialet med andra ämnen och genom att påverka materialet med ett elektriskt fält. I princip all modern elektronik bygger på komponenter av hThis thesis focuses on electron transport in semiconductor InAs/InP and InSb nanowire quantum devices. However, first the temperature dependence of classical charge transport in InSb nanowire field-effect transistors, FETs, is characterized, using InAs nanowire FETs as a reference. We find that the InSb FETs, in the same way as InAs FETs, are n-type with good current saturation and low voltage ope

Gas turbines emissions, NOX in particular, have negative impact on the environment. To limit the emissions gas turbine burners are constantly improved. In this work, a fourth generation SIT (Siemens Industrial Turbomachinery) burner is studied to gain information about the formation of NOX emissions. The gas mixtures for the full burner are limited to natural gas with different nitrogen dilutions.

1. Theory predicts that the processes generating biodiversity after disturbance will change during succession. Comparisons of phylogenetic and functional (alpha and beta) diversity with taxonomic diversity can provide insights into the extent to which community assembly is driven by deterministic or stochastic processes, but comparative approaches have yet to be applied to successional systems. 2.

Airway epithelial repair, by cell migration over a denuded, intact basement membrane, occurs rapidly in vivo. The present study examines microcirculation-derived factors in the reepithelialization process in the guinea pig. A well-defined tracheal zone was gently deepithelialized; no bleeding occurred and the basement membrane was left intact. Plasma exudation was visualized by use of iv colloidal