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Socio-economic differences in health and mortality are substantial and increasing today in many developed countries. The sources of these differences remain debated. There is an expanding literature showing that early-life conditions are linked to health in adulthood and old age. However, our knowledge about whether beneficial treatments in early life influence later health is still limited. Using
Current European regulations on producer responsibility provide limited incentives for ecodesign practices among manufacturers. Additional incentives for 'design for resource efficiency' and 'design for recycling' could be provided through mandatory design standards set under the Ecodesign Directive. While European manufacturers have become increasingly positive towards eco-design standards for en
Fuel cells, redox flow batteries and some water desalination technologies such as reverse osmosis and electrodialysis require efficient ion exchange membranes to perform in an optimum way. Thus, by enhancing the properties of these membranes there is a possibility to improve this type of applications and technologies. Depending on the specific application, anion or proton exchange membranes with g
Dendritic cells (DC) are a heterogeneous lineage of bone-marrow-derived leukocytes that serve as the link between innate and adaptive immunity. They are professional antigen-presenting cells that play an important protective and regulatory role in both health and disease. This thesis is based upon six original papers that deal with the function and transcription of human DCs, with focus on their r
In the Swedish context teaching at primary and secondary school is combined with collaborative exercises in a variety of subjects. These collaborative moments can be in the form of mini projects that groups of students are supposed to present to the classmates when fulfilled. A collaborative moment may also be an exercise that the students solve together. The main idea is thus that the students le
Background: Little or no knowledge is available about which service is offered to patients with heart failure in primary care. Aims: To describe nurse-led follow-up of patients with heart failure in primary care in Sweden. Methods and results: A questionnaire was sent to all primary health care centres in Sweden and 6 10 of 939 centres returned the questionnaire. Special nurses had designated time
Quaternary glacial stratigraphy and relative sea-level changes reveal at least two glacial expansions over the Chelyuskin Peninsula, bordering the Kara Sea at about 77°N in the Russian Arctic, as indicated from tills interbedded with marine sediments, exposed in stratigraphic superposition, and from raised beach sequences mapped to altitudes of at least up to ca. 80 m a.s.l. Chronological control
Brown C, Hasson H, Thyselius V, Almborg A-H. Post-stroke depression and functional independence: a conundrum. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01595.x. © 2011 John Wiley & Sons A/S. Objectives - People who suffer a stroke are at risk of developing post-stroke depression (PSD). Not only does this lower their quality of life but it also increases their risk of another stroke or d
Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. Due to improved hydrolytic stability, lactam (inner amide) analogues of gangliosides sho
With the ultimate goal to study milk folate bioavailability, a reverse-phase HPLC technique was developed and compared with a radioprotein binding assay. All methods showed similar ranges for folates in cow’s milk, with the variation attributed to seasonal variations and the use of different starter cultures. Most cheese varieties contained slightly higher values for whey cream cheese. Studies usi
Mankind has always used animals as the Other, to compare himself with them. Animals have provided the mirror in which mankind has defined himself . In their perceived similarities and dissimilarities with humans, he has distinguished the boundaries which separates him from the Other. Since antiquity, this relationship has been lively debated between at least two groups of interpreters. The "dualis
Insulin resistance is a hallmark of type 2 diabetes, an increasingly common disorder. The cause of insulin resistance is supposedly failures in the processes used by insulin to signal to the interior of its target cells. These failing steps are still unknown, most probably because of incomplete knowledge of how the insulin signals are transmitted. Since insulin resistance is strongly linked to obe
Abstract in Danish Nytter rollatorer og elkørestole? Mennesker med gangbesvær kan opleve manglende muligheder for at udføre aktiviteter, som er forudsætningen for at leve et godt liv og deltage i samfundslivet på lige fod med andre borgere. Desuden vil nedsat mobilitet føre til inaktivitet, der har helbredsmæssige konsekvenser. Derfor sættes der fra samfundets side ind med rehabilitering, blandt Rollator and powered wheelchair interventions are often applied to make participation possible for citizens with limited walking capacity. However, the research-based knowledge about outcomes is insufficient for societal prioritisation purposes and for quality development of assistive technology within occupational therapy contexts. In this thesis outcomes in terms of user satisfaction, participat
Smooth muscle cell (SMC)-specific deletion of transforming growth factor beta (TGF-beta) signaling would help elucidate the mechanisms through which TGF-beta signaling contributes to vascular development and disease. We attempted to generate mice with SMC-specific deletion of TGF-beta signaling by mating mice with a conditional ("floxed") allele for the type 11 TGF-beta receptor (tgfbr2(flox)) to
Objective The effect of salt restriction on blood pressure is under intense debate. We tested the effect of 100 mmol salt reduction on ambulatory blood pressure (ABP) in 46 Swedish individuals, 39 of whom completed the study, using a double-blind, placebo-controlled, crossover design. Furthermore, we tested whether the basal plasma concentration of renin or N-terminal atrial natriuretic peptide (N
Stories of achievements is a study concerning uses of the notion of organizational performance. It shows the variety of meanings given the notion in dictionaries, management literature, sports, and performance indicators; it also explores how such meanings are constructed and how they are attached to this notion in new contexts, such as in the activity reports of public libraries. Examining uses
Objectives: At the request of the European Commission and in the framework of the European Machinery Directive, research was performed in five different laboratories to develop specifications for surface temperature limit values for the short-term accidental touching of the fingertip with cold surfaces. Methods: Data were collected in four laboratories with a total of 20 males and 20 females perfo
Genome-wide association studies (GWASs) have identified several single-nucleotide polymorphisms (SNPs) influencing the risk of Hodgkin's lymphoma (HL) and demonstrated the association of common genetic variation for this type of cancer. Such evidence for inherited genetic risk is also provided by the family history and the very high concordance between monozygotic twins. However, little is known a
Owing to complex direct and indirect effects, impacts of higher trophic levels on plants is poorly understood. In tropical agroecosystems, ants interact with crop mutualists and antagonists, but little is known about how this integrates into the final ecosystem service, crop yield. We combined ant exclusion and introduction of invasive and native-dominant species in cacao agroecosystems to test wh
