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In this group we study how metastatic processes depend on suppression of the immune response and how the immune system actually instead promotes breast cancer metastasis. The research has a strong translational character with clinical collaborations and primary material as base in all projects. The focus is on immunosuppressive cell populations and metastatic processes in breast cancer. Understand
Our research is focused on the regulation of the complement system in health and disease. Complement is crucial part of innate immunity and thus protects host from infections and contributes to removal of dying cells. We study involvement of complement in pathology of rheumatic and inflammatory diseases as well as several types of cancer. Further, we investigate strategies developed by bacterial
Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism. While the interactions between bacteria and platelets have been described in detail for many Gram-positive pathogens, little research has been carried out with SBSEC in this
Block transmission over noisy communication channels is characterized by two performance criteria: the bit error probability P/sub b/ and the block error probability P/sub B/. If P/sub B/ goes to zero when N/spl rarr//spl infin/ (where N denotes the length of the permutors), P/sub b/ also must go to zero for all symbols in the block but, in general, the reverse is not true. Therefore we formulate
Throughout the past decade, neural network-based vision has been increasingly integrated into robots. It is well-known, however, that neural networks can be unreliable, especially when faced with inputs that differ from their training data. With the goal of making neural network-based vision more reliable for robotic applications, this thesis explores uncertainty estimation, and adaptability.A
Color is the most obvious and easily determined soil property that can provide crucial information about soil composition. The NIX™ Pro color sensor (Nix) presents a user-friendly alternative to the traditional Munsell manual method, with reduced sensitivity to environmental and human factors. Therefore, a new method was developed to use Nix in combination with machine learning to quickly and affo
Virtually from Lund Observatory, March and April 2021 Scientific motivation The characterization of stellar properties is crucial to studies of Galactic archaeology, exoplanets, and stellar structure and evolution. To ensure the success of these science pillars, a well-established and well-understood set of reference stars is needed. Current and future large surveys of the Milky Way are set to det
https://www.astro.lu.se/lundreferencestars - 2026-06-25
https://www.historiskamuseet.lu.se/english - 2026-06-25
OBJECTIVE: Pulsatile wall motion has been suggested as a means by which to evaluate abdominal aortic aneurysms after exclusion from the circulation to determine whether the treatment has been effective. The objective of this study was to investigate the relations between pulsatile wall motion and both the mean and pulse pressures within the aneurysmal sac for both patent and thrombosed endoleaks.
The favorable pharmacokinetics of MMC, used during intraperitoneal chemotherapy, has been reported in several studies [11-19]. A major safety issue in studies using intraperitoneal chemotherapy perfusion is the resulting systemic drug exposure. The AUCplasma is determined by the dose, the clearance, and the fraction absorbed from the peritoneal cavity. The reported mean plasma peak concentrations
Our research uses advanced technology to generate neurons from novel cell sources with the aim to extensively define the subtype and function of the generated neurons and their potential for therapeutic use in the future. For this we are using reprogramming technology in animal models or human stem cell culture system, together with electrophysiology, RNA sequencing, tracing technologies and cell Our research uses advanced technology to generate neurons from novel cell sources with the aim to extensively define the subtype and function of the generated neurons and their potential for therapeutic use in the future. For this we are using reprogramming technology in animal models or human stem cell culture system, together with electrophysiology, RNA sequencing, tracing technologies and cell
