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Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. Methods We performed a two-stage meta-analysis on more than 78 000 participants. In stage 1, we synthesised data from eight GWAS whereas data from 10 centres wer
Det är dyrt att äga en häst, en del av denna kostnad är försäkringspremien. Försäkringen kan dock komma väl till hands då en skada inträffar. Bara för att man har sin häst försäkrad innebär det inte att alla skador hästen kan få är ersättningsbara. Uppsatsen kommer att behandla olika problem vid försäkring av häst. Det finns vissa skillnader mot ''vanliga'' sakförsäkringar. Försäkr
Kosovo, världens 193:e land, blir den sjätte staten som bildats från den serbdominerade jugoslaviska federationen sedan 1991, efter Slovenien, Makedonien, Bosnien och Montenegro som blev världens nyaste stat 2006. Kosovos status som självständig stat är dock fortfarande omstridd. Frågan om Kosovo är ett internationellt subjekt som har en rätt till externt självbestämmande och därmed är ett subjektKosovo, the world’s 193rd country, will be the sixth state carved from the former Serbian-dominated Yugoslav federation since 1991, after Slovenia, Croatia, Macedonia, Bosnia and Montenegro, which became the world’s newest state in 2006. Kosovo’s statehood is, however, still disputed. The question if Kosovo is a subject that has a right to external self-determination and therby hold international
The idea for nature based research design emerged in preparation of a workshop and subsequent exhibition regarding minimal surfaces, supervised by Andreas Hopf, Senior Lecturer at Lund University School of Industrial Design, and supported by Prof. Dr. Konrad Polthier (Chair Mathematical Geometry Processing, FU Berlin) at the DESIGNMAI digital crafts event in Berlin in 2007, for which Swedish desig
Student recruitment? - Three teachers? thoughts concerning children's first experiences in municipal arts and music schools. The aim of this thesis is to explore three teacher' experiences of recruitment of students to arts and music schools. The thesis includes thoughts about how teachers can inspire students and why the orchestral string bass is an infrequent choice of instrument to stud
The main purpose of this study is to inquire whether music can function as a supportive and compensating tool for children from various kinds of social exposure. Eurhythmics is the musical method focused on, since it consciously works out of a socializing perspective. The study involves a scheme with poor children in Argentin (autumn 2005) and is based upon two interviews with women working profes
Abstrakt Begreppet främlingsfientlig använd's ofta i media om Sverigedemokraterna efter valframgångarna 2006. Indirekt ger detta väljarna samma stämpel. Är det främlingsfientlighet som får väljarna att rösta på partiet? Är det något annat väljarna vill ha sagt med sina röster? Vad tror Sverigedemokraterna's politiker är anledningen bakom framgången? Det vill jag ta reda på i denna uppsat&
Mutation-bearing peptide ligands from mutated nucleophosmin-1 (NPM1) protein have been empirically found to be presented by HLA class I in acute myeloid leukemia (AML). We hypothesized that HLA genotype may impact allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes in NPM1-mutated AML owing to differences in antigen presentation. We evaluated the effect of the variable of predic
The aim of this work is to investigate different methods to solve the problem of allocating the correct amount of resources (network bandwidth and storage space) to video camera systems. Here we explore the intersection between two research areas: automatic control and game theory. Camera systems are a good example of the emergence of the Internet of Things (IoT) and its impact on our daily lives
Groundwater is a crucial source of water supply in drought conditions, and an auxiliary water source in wet seasons. Due to its increasing importance in view of climate change, predicting groundwater level (GWL) needs to be improved to enhance management. We used adaptive neuro-fuzzy inference systems (ANFIS) to predict the GWL of the Urmia aquifer in northwestern Iran under various input scenario
What is degrowth and what are its implications for political economy? Divided in three parts, this dissertation explores the why, what, and how of degrowth.The first part (Of growth and limits) studies the nature, causes, and consequences of economic growth. Chapter 1: Understanding economic growth answers a series of questions about the nature of economic growth: What is it exactly that grows? By
Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of
Denna avhandling undersöker vetenskapens roll i den politiska processens tidiga stadier. Detta görs genom att studera hur "geoengineering" kommer upp på den politiska agendan. Begreppet ”geoengineering” används även på svenska och beskriver en uppsättning idéer om hur man stabiliserar den globala temperaturen genom att ingripa i jordens miljösystem. Begreppet mötte stark skepsis i det vetenskapligThis thesis examines the role of science in the earliest stages of the political process. It does this by studying the emergence of ‘geoengineering’ on the political agenda. The term describes a set of ideas on how to stabilize global temperature by intervening into the Earth’s natural systems, and was subject to a strong taboo in the scientific community until the mid-2000s. Yet within a decade,
Background: Widespread implementation of Alzheimer's disease biomarkers in routine clinical practice requires the establishment of standard operating procedures for pre-analytical handling of cerebrospinal fluid (CSF). Methods: Here, CSF collection and storage protocols were optimized for measurements of β-amyloid (Aβ). We investigated the effects of (1) storage temperature, (2) storage time, (3)
Objectives: The aim is to estimate agreement between two-dimensional transvaginal ultrasound (2D-TVS) and three-dimensional volume contrast imaging (3D-VCI) in diagnosing deep myometrial invasion (MI) and cervical stromal involvement (CSI) of endometrial cancer and to compare the two methods regarding inter-rater reliability and diagnostic accuracy. Methods: Fifteen ultrasound experts assessed off
