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The history and status of dopamine cell therapies for Parkinson's disease Received: 23May 2024 Revised: 26 June 2024 Accepted: 1 July 2024 DOI: 10.1002/bies.202400118 R E V I EW E S S AY Prospects & Overviews The history and status of dopamine cell therapies for Parkinson’s disease Roger A. Barker1 Anders Björklund2 Malin Parmar2,3 1Department of Clinical Neurosciences and Cambridge StemCell Insti
Objectives: To assess the health-related quality of life (HRQOL) of patients with mucopolysaccharidosis (MPS) and their caregivers and to quantify the disease-related costs from a societal perspective. Methods: In the context of a multi-country study of rare diseases (BURQOL-RD project), a cross-sectional survey was performed among MPS patients in seven European countries. Data on demographic char
Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Thus, the clinical features and outcomes are not well described. Cases of histologically confirmed CNS HL diagnosed between 1995 and 2015 were retrospectively identified in institutional (n = 7), national (n = 2), and cooperative group (n = 1) databases. We screened 30,781 patients with HL in our combined data
A paradigm shift is emerging in higher education especially regarding how universities should address personalized and collaborative mobile learning. Experiences from three international benchmarking-projects through the European Association of Distance teaching Universities (EADTU), the European Centre for Strategic Management of Universities (ESMU) and the First dual mode benchmarking club on qu
OBJECTIVE: Communication about patients' values, goals, and prognosis in serious illness (serious illness communication) is a cornerstone of person-centered care yet difficult to implement in practice. As part of Serious Illness Care Program implementation in five health systems, we studied the clinical culture-related factors that supported or impeded improvement in serious illness conversations.
Introduction Autistic persons experience problems with movements and body awareness in everyday functionality, expressed in affected movement quality. Yet, there is a knowledge gap about the effects of interventions targeting these aspects in autistic persons. Objective To evaluate effects of Basic Body Awareness Therapy (BBAT) and treatment-as-usual (TAU), compared to TAU alone on movement qualit
INTRODUCTION: Intracranial haemorrhage (ICH) is the most serious complication in infants and children with severe congenital bleeding disorders causing substantial mortality and long-term neurological morbidity. The neonatal period carries the highest risk, particularly in severe haemophilia and rare factor deficiencies. We review the epidemiology, risk factors, prevention, recognition, management
Sports-related concussions (SRCs) typically occur when the brain is hyperthermic. Acute head-and-neck cooling should, therefore, reduce the brain's metabolic demands, with the potential to improve recovery following an SRC. Elite ice hockey players who underwent head-and-neck cooling after sustaining a concussion (SRC) showed reduced return-to-play times, although further investigation is warrante
häls – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: häls Hälsovetenskapens dag – för en bättre hälsa genom livet 2016-11-08 Torsdagen den 17 november mellan 13.30 – 16.30 kan du komma och lyssna på föreläsningar om forskning kring nya arbetssätt för en bättre hälsa genom livet. M
https://www.vetenskaphalsa.se/tag/hals/ - 2026-05-31
Background: The ability to adapt and habituate based on prior experiences is important for human movement control, fall prevention and for the ability to enhance performance during various human activities. However, little is known about the ability for the elderly to adapt to balance perturbations in the lateral direction. Objective: To determine whether adaptation, i.e., the ability to adjust po
Sammanfattning Den kanske största miljöpolitiska utmaningen inom Europa är för närvarande frågan om hur det är möjligt att på ett effektivt och ändamålsenligt sätt uppnå miljömålen i syfte att skapa en hållbar utveckling i samhället. Trenden har gått från att tillgripa lagstiftningsåtgärder till att via marknadsbaserade styrmedel försöka involvera olika marknadsaktörer att på egen hand bli delaktSummary Potentially one of the greatest environmental policy challenges in the European Union is the question of how to efficiently and effectively achieve environmental goals through which society can correct for and obtain a level of sustainable development. The trend has gone from one of command and control legislation towards using more market-based instruments that seek to involve the differ
Studien syftade till att undersöka om eventsegmentering kan utgöra en grund för minnesbaserad tidsbedömning i det episodiska minnet och huruvida objektets semantiska association till kontexten påverkar integrationen av minnet. Eventsegmentering etablerar upplevelsen av en händelse genom att särskilja vad som händer nu från det som hände nyss och bryter därmed ner tidsförlopp till enstaka händelserThe study aimed to investigate whether event segmentation can provide a basis for memory-based time assessment of episodic memory and whether object association to the context affects subsequent memory integration. Event segmentation establishes the experience of an event by distinguishing what is happening now from what just happened and thus breaks down the time-course of an event to include sub
As society becomes more ecologically conscious there is a push toward the use of materials with a smaller environmental burden, one of these materials is glulam (GLT), which has gained a lot of traction in recent years not only for ecological reasons but for its ease in manufacture, transport, noise dampening, etc. The focus of this project was to evaluate the influence of different joint configu
Dangdut as the most popular music in Indonesia is highly sexualized on its representation of women despite the fact that Indonesia is a religious country. Dangdut’s sexualization is prominent on its performance, lyrics and culture. Banality, is the face of dangdut. During its public shows, many of the male audiences are more often than not intoxicated and engage in physical fights. Yet to date, th
förebygga ohälsa – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: förebygga ohälsa Hälsovetenskapens dag – för en bättre hälsa genom livet 2016-11-08 Torsdagen den 17 november mellan 13.30 – 16.30 kan du komma och lyssna på föreläsningar om forskning kring nya arbetssätt för en bät
https://www.vetenskaphalsa.se/tag/forebygga-ohalsa/ - 2026-05-31
Background and objective The Scania Accelerated Intermittent Theta-burst Implementation Study (SATIS) aimed to investigate the tolerability, preliminary effectiveness, and practical feasibility of an accelerated intermittent theta burst stimulation (aTBS) protocol in treating depression. Methods We used an open-label observational design, recruiting 20 patients (aged 19–84 years) from two public b
Topiramate is biochemically classified as a fructopyranose sulphamate. Discovered as early as 1979, during middle 1980's it was approved in many countries for the treatment of epilepsies and migraine prevention. More recently, in the experimental stage, possible new indications have been disclosed: treatment of obesity, bipolar disorder, also cessation of smoking, neuropathic pain, cerebral pseudo
Technological and policy solutions for transitioning to a fossil-free society exist, many countries could afford the transition, and rational arguments for rapid climate action abound. Yet effective action is still lacking. Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avoid potentially catastrophic futures. This is despite 30 years o
Older people with arrhythmias comprise a large group requiring complex care, posing many healthcare challenges. Rapid growth of the older population demands a better understanding of the needs of this patient group. The aim of this thesis was to investigate arrhythmia prevalence, incidence, survival, and experiences from the perspective of a geriatric population (aged 60+ years), and to examine th
