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The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. In the present thesis I studied the silencing of transgenes induced upon differentiation of neural pro
Melanoma is an aggressive disease that arises from deregulated signaling events in melanocytes. The KIT receptor tyrosine kinase and the Microphthalmia-associated transcription factor (MITF) are two essential components that are required for the normal physiology of melanocyte development and function. Consequently, aberrant activities of these factors are involved in the development of melanoma.
Popular Abstract in Swedish Som en blixt från klar himmel drabbas en ung, och till synes frisk person, av hjärnblödning. Denna stroke leder till demens och efterföljande nya blödningar leder slutligen till en för tidig död. Man har kunnat visa att denna sjukdom beror på att en variant av ett visst protein, cystatin C, tvinnar ihop sig till rep-liknande långa fibriller. Dessa fibriller ansamlas sedAmyloidosis is a group of diseases characterized by a change in protein conformation resulting in aggregation and tissue deposition of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic and persons carrying the corresponding gene suffer from massive cerebral amyloidosis leading to brain hemorrhage and death. Amyloidogenic proteins like cystatin C and prion protein
Photomultiplier tube (PMT) nonlinearities relevant for single shot high-speed lifetime phosphor thermometry were investigated by simulating decay curves with a light emitting diode (LED) at repetition rates between 1 Hz and 10 kHz. The PMT gain, LED decay time, and background radiant flux were also varied to investigate their impact on the measured decay time error. Errors in the measured decay tiPhotomultiplier tube (PMT) nonlinearities relevant for single shot high-speed lifetime phosphor thermometry were investigated by simulating decay curves with a light emitting diode (LED) at repetition rates between 1 Hz and 10 kHz. The PMT gain, LED decay time, and background radiant flux were also varied to investigate their impact on the measured decay time error. Errors in the measured decay ti
Primär hyperparathyroidism, pHPT, är en relativt vanlig endokrinologisk sjukdom som karaktäriseras av förhöjd utsöndring av bisköldkörtelhormon, PTH, i förhållande till kalciumnivån i blodet. Sjukdomen är vanligast hos äldre och kvinnor, och orsakas oftast av en godartad tumör i en bisköldkörtel (80–85% av fallen) eller mer diffus förstoring av flera bisköldkörtlar. Bisköldkörtlarnas fysiologiska
10 oktober 2025 10:00 till 11:00 | Workshop Creating a research network to foster woman's partcipation in technoscience. An online lecture and on-site seminar in the serie Girls Just Want To Have Sc(AI)ence.Topic: Critical Robotic Dialogues: Exploring Robots in the Present and FutureWhen & where: 10 October 2025 at 10:00–11:00, online only via Zoom. Link by registration. Invited speakersIolanda L
https://www.lu.se/evenemang/girls-scaience-4-critical-robotic-dialogues-exploring-robots-present-and-future - 2026-07-24
Professorsinstallation Lunds universitet | aulan | 7 september 2012 kl 16.00 3 Förord Välkomna till den högtidliga professorsinstallationen! Ordet universitet kommer av det latinska universitas, som betyder ungefär helhet, det hela. Detta ord har samband med universus med betydelsen hel, allomfat- tande, egentligen vänd åt ett håll liksom med universum och universell. Universitas blev under högmed
https://www.lu.se/sites/www.lu.se/files/professorsinstallationsbroschyr_sep2012.pdf - 2026-07-23
Ett projekt inom ArtCollab An anthology that examines the evolution of socially-engaged art practice, or social practices in a global context Foto: Maj Hasager This project focusses on the research phase for an anthology with the working title Iceberg works which is a collaboration between Sue Bell Yank (researcher and Director of Clockshop in L.A.) and Maj Hasager (Artist, Professor and head of
https://www.thm.lu.se/iceberg-works - 2026-07-23
Due to the refugee crisis that evolved in 2015, the Swedish Government introduced a new refugee policy in order to decrease the number of asylum seekers arriving in Sweden. This new refugee policy resulted, among other things, in a temporary law that limits the possibilities to receive a residence permit in Sweden. The temporary law has received a great amount of criticism from several consultatio
The key step in the reaction mechanism of multicopper oxidases (MCOs)-the cleavage of the O-O bond in O-2-has been investigated using combined quantum mechanical and molecular mechanical (QM/MM) methods. This process represents a reaction pathway from the peroxy intermediate after it accepts one electron from the nearby type-1 Cu site to the experimentally-observed native intermediate, which is th
Anthropogenic N deposition may change soil conditions in forest ecosystems as demonstrated in many studies of coniferous forests, whereas results from deciduous forests are relatively scarce. Therefore the influence of N deposition on several variables was studied in situ in 45 oak-dominated deciduous forests along a N deposition gradient in southern Sweden, where the deposition ranged from 10 to
Abstract in UndeterminedRelevant source area of pollen (RSAP) and pollen productivity for 11 key taxa characteristic of the pasture woodland landscape of the Jura Mountains, Switzerland, were estimated using pollen assemblages from moss polsters at 20 sites. To obtain robust pollen productivity estimates (PPEs), we used vegetation survey data at a fine spatial-resolution (1 x 1 m(2)) and randomize
Readouts that define the physiological distributions of drugs in tissues are an unmet challenge and at best imprecise, but are needed in order to understand both the pharmacokinetic and pharmacodynamic properties associated with efficacy. Here we demonstrate that it is feasible to follow the in vivo transport of unlabeled drugs within specific organ and tissue compartments on a platform that appli
Surface water is vital resources for terrestrial life, while the rapid development of urbanization results in diverse changes in sizes, amounts, and quality of surface water. To accurately extract surface water from remote sensing imagery is very important for water environment conservations and water resource management. In this study, a new Multi-Band Water Index (MBWI) for Landsat 8 Operational
Purpose: Sustainability is an area of increasing interest for industry and its stakeholders, and some companies now aspire to address sustainability issues (e.g. carbon emissions) at strategic and operational levels. As companies are exploring the issues, they attempt to embed sustainability in their planning and management systems. It is at this point that the domains of environmental concern and
To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel
This thesis has been performed in the ethylene oxide plant at Akzo Nobel in Stenungsund. Ethylene oxide is an important ethylene based intermediary compound. The primary use for ethylene oxide is in the manufacture of derivatives such as ethylene glycol, surfactants and ethanolamine’s. In the production of ethylene oxide, ethylene and oxygen reacts over a silver catalyst surface. Mainly two react
Immunförsvaret och tumörer i duell – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Immunförsvaret och tumörer i duell 2017-10-24 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Karin Leandersson installerades som professor i experimentell
https://www.vetenskaphalsa.se/immunforsvaret-och-tumorer-i-duell/ - 2026-07-21
EU vill förebygga blödningar hos nyfödda – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök EU vill förebygga blödningar hos nyfödda 2012-05-09 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Trombocytopeni innebär en brist på blodplättar, v
https://www.vetenskaphalsa.se/eu-vill-forebygga-blodningar-hos-nyfodda/comment-page-1/ - 2026-07-21
