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Professor Mona Holmqvist har utsetts till ledamot i Vetenskapsrådet Professor Mona Holmqvist har utsetts till ledamot i Vetenskapsrådet Av Annika Diehl - Publicerad den 21 februari 2025 Professor Mona Holmqvist har utsetts till ledamot i Vetenskapsrådets utbildningsvetenskapliga kommitté för mandatperioden 2025 - 2027. Vetenskapsrådets kommitté för utbildningsvetenskap stödjer forskning och utbild

https://www.uvet.lu.se/article/professor-mona-holmqvist-har-utsetts-till-ledamot-i-vetenskapsraadet/ - 2026-09-19

Föreläsning på UR: Elevens roll i skolan i ett historiskt perspektiv Föreläsning på UR: Elevens roll i skolan i ett historiskt perspektiv Av Caroline Cabot - Publicerad den 15 maj 2024 Mona Holmqvist, professor på institutionen för utbildningsvetenskap vid Lunds universitet. Foto: UR Vilka grupper av elever gynnas eller missgynnas av det rådande skolsystemet? Och hur har elevens roll i skolan förä

https://www.uvet.lu.se/article/foerelaesning-elevens-roll-i-skolan-i-ett-historiskt-perspektiv-1/ - 2026-09-20

One of the key ecological processes affected by climate change is plant carbon uptake. However, there is substantial uncertainty about how plant carbon uptake will respond to warming in mountain ecosystems, which are known for sharp temperature gradients and abrupt shifts in vegetation structure. Specifically, we lack an understanding of whether these response trajectories over time will be linear

Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory

The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of environmental and genetic factors on variation in the parameters of innate and adaptive immune cells in homeostatic conditions, we combined standardized flow cytometry of blood leukocytes and genome-wide DNA genotyping of 1,000 healthy, unrelat

The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi). In the ZUMA-2 single-arm trial, brexucabtagene autoleucel (brexu-cel; autologous anti-CD19 CAR T-cell therapy) demonstrated high rates of durable response

Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15–20% of families fitting MODY criteria do not have mutations in any of the known genes. These families provide a rich resource for the identificat

Background Although human leukocyte antigen (HLA) DQ and DR loci appear to confer the strongest genetic risk for type 1 diabetes, more detailed information is required for other loci within the HLA region to understand causality and stratify additional risk factors. The Type 1 Diabetes Genetics Consortium (T1DGC) study design included high-resolution genotyping of HLA-A, B, C, DRB1, DQ, and DP loc

The intronic SNP rs7903146 in the T-cell factor 7-like 2 gene (TCF7L2) is the common genetic variant most highly associated with Type 2 diabetes known to date. The risk T-allele is located in an open chromatin region specific to human pancreatic islets of Langerhans, thereby accessible for binding of regulatory proteins. The risk T-allele locus exhibits stronger enhancer activity compared to the n

The Sardinian dhole (Cynotherium sardous) was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene. Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African hunting doThe Sardinian dhole (Cynotherium sardous)1 was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene.2-5 Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African huntin

PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin

OBJECTIVE: In a multicenter cohort of probable dementia with Lewy bodies (DLB), we tested the hypothesis that β-amyloid and tau biomarker positivity increases with age, which is modified by APOE genotype and sex, and that there are isolated and synergistic associations with the clinical phenotype. METHODS: We included 417 patients with DLB (age 45-93 years, 31% women). Positivity on β-amyloid (A+)

INTRODUCTION: We examined whether sex modifies the association between APOE ε2 and cognitive decline in two independent samples. METHODS: We used observational data from cognitively unimpaired non-Hispanic White (NHW) and non-Hispanic Black (NHB) adults. Linear mixed models examined interactive associations of APOE genotype (ε2 or ε4 carrier vs. ε3/ε3) and sex on cognitive decline in NHW and NHB p

Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o

Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-Cas9 screen in a human MDS-derived cell line, MDS-L, and identify TOPORS as a loss-of-function target that synergizes with HMAs, reducing leukemic burden and i

Fluid biomarkers are revolutionizing the diagnosis and management of neurodegenerative diseases by enabling earlier diagnosis and disease monitoring. In particular, blood-based biomarkers have emerged as a minimally invasive and scalable alternative to cerebrospinal fluid analysis. Recent advances in blood-based tau biomarkers have shown high diagnostic accuracy for Alzheimer’s disease (AD). Other

Människohandel för sexuella ändamål är ett komplext fenomen och ett globalt problem som både berör och upprör. Människohandel är gärningar som syftar till ett efterföljande utnyttjande av offret och ett brott där skyddssyftet är personlig frihet och frid. Det är också ett sammansatt problem, det vill säga att det innefattar bland annat brott mot mänskliga rättigheter, organiserad brottslighet, migHuman trafficking for sexual purposes is a complex phenomenon and a global problem that upsets. Human trafficking is an acts aimed to subsequent exploit the victim and a crime which aim the protection of personal liberty and peace. It is also a complex problem, that includes human rights violations, organized crime, migration, gender, poverty and social, economic and political differences between

Att Söka efter Higgs-Bosonen Den dittills oupptäckta Higgs-bosonen upptäcktes förra året på CERN i Schweiz. Denna partikel har en central roll i partikelfysiken, och var därför oerhört viktig att upptäcka. Då den lever väldigt kort tid går den inte att detektera direkt. Detta arbete söker finna massan hos Higgs-bosonen, och använder sig då av fallet då den sönderfaller till fyra myoner. Higgs-bosoAbstract Within the Standard Model of particle physics, there was only one undiscovered fundamental particle. This was the Higgs boson. In July 2012, the announcement was made that a Higgs like particle had been discovered by the ATLAS Collaboration and the CMS Collaboration at CERN. The aim of this Bachelor’s thesis was to use data collected by the ATLAS detector facility to estimate the mass of

The Swedish government has in July 2010 incorporated a legislation regarding the possibility to deduct a loss incurred by a non-resident subsidiary, from the parent company’s taxable income. This Law is based on the Swedish administrative court’s interpretation of the European Union Court’s judgement of the Marks & Spencer case and the Oy AA case. The law is in my opinion not completely compat

Till följd av finanskrisen förlorade konsumenter genom placeringar i riskfyllda finansiella instrument stora delar av sina investeringar. Under åren 2008 och 2009 inkom fler klagomål till Finansinspektionen och Konsumentverket jämfört med tidigare år om att många konsumenter via rådgivning rekommenderats produkter som inte motsvarat den risk de varit beredda att ta eller att information om risken The aftermath of the financial crisis meant that many consumers lost parts of their investments because they had invested their savings in risky financial instruments. Between the years of 2008 and 2009, the Swedish Financial Supervisory Authority, Finansinspektionen, and the Swedish Consumer Agency, Konsumentverket, received more complaints, compared to previous years, regarding financial advisor