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The transcription factor Sox4 has been proposed to underlie the increased type 2 diabetes risk linked to an intronic single nucleotide polymorphism in CDKAL1. In a mouse model expressing a mutant form of Sox4, glucose-induced insulin secretion is reduced by 40% despite normal intracellular Ca2+ signaling and depolarization-evoked exocytosis. This paradox is explained by a fourfold increase in kiss
Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group
Title: Between few rules and strong culture: a qualitative study on culture and identity in a knowledge-intensive organization without explicit formalities. Seminar date: 3rd of June, 2025. Course: FEKH49, Degree Project Undergraduate Level, Business Administration, Undergraduate level, 15 ECTS. Authors: Klara Andersson, Julia Hesslevik & Sophie Linder. Advisor: Stefan Sveningsson. Keywords:
Title: The art of combining availability and exclusivity – A dialectical analysis of the tension between premium and luxury Seminar date: 2025-06-05 Course: FEKH29, Business Administration: Degree Project in Marketing, Undergraduate level, 15 credits Authors: Pontus Sölve, Hannes Hemgren, Julia Johansson Mozaffari Advisor: Jon Bertilsson Key words: Brand, Premium, Luxury, Masstige, New luxu
On 1 July 2022, the Swedish Act (1988:254) on the Prohibition of Knives and Other Dangerous Objects (the Swedish Knife Act), which criminalizes possession of knives and other dangerous objects in public places, was amended. Through the amendment, four criteria were introduced to the statutory text, which are to be given particular consideration when assessing whether a violation of the law is to b
Fankulturen har idag kunnat ta plats på en större arena tack vare internet i form av fan communities och fansajter. Detta har lett till att fansen idag har enklare tillgång till andra fans, interaktion och livsstilsbildande. Gemenskap är ett socialt fenomen som är en intressant och en central aspekt att undersöka på dessa digitala plattformar, eftersom gemenskapsaspekten för människan är relativt
Until July 1, 2018, Swedish legislation lacked a general remedy for delays in the authorities’ handling of cases. With the introduction of section 12 of the Public Administration Act the remedy, often referred to as the delay action, came to change the Swedish Migration Agency’s routine handling of citizenship applications. Authorities would henceforth not be able to act passively in the handling
Häktning är ett straffprocessuellt tvångsmedel som kan användas vid utredning av misstänkt brottslighet. Häktning kan under vissa förutsättningar kombineras med restriktioner, med följd att den häktade isoleras från omvärlden. Det svenska häktningsinstitutet har sedan tidigt 90-tal återkommande erhållit internationell kritik. Kritiken har bland annat avsett att det saknas tidsgränser för hur längeRemand is a coercive measure which may be used while investigating a suspected crime. Remand may, under certain conditions, be combined with restrictions, resulting in the detainee being isolated from the outside world. The Swedish remand institute has received international criticism since the early 1990s. The criticism has, among other things, been related to the lack of time limits for how long
The shore protection regulation has a long tradition in Sweden, with increas-ing emphasis placed over time on the need to protect shorelines from devel-opment. In July 2025, legislative amendments entered into force, and an ongoing inquiry is examining the possibility of more flexible legislation. This thesis employs the legal dogmatic method to examine the shore protec-tion regulation with the ai
On July 22, 2022, a crown witness system was introduced with the aim of increasing prosecution rates and breaking the prevailing culture of silence. This system includes a basis for sentence reduction regarding participation in the investigation of another's criminal activity. The idea behind the crown witness system is to increase incentives for suspects to cooperate in order to solve more se
Sverige har en lång tradition av en flexibel arbetsmarknad där arbetstagare fritt kunnat förflytta sig mellan offentlig och privat sektor. Övergångar av detta slag är i många delar positivt och genererar ett erfarenhetsutbyte som är till gagn för båda sektorer. I samband med övergång från anställning i offentlig till privat verksamhet kan emellertid så kallad svängdörrsproblematik uppstå. Denna prSweden has a long tradition of a flexible labor market where employees have been able to freely move between the public and private sectors. Transitions of this kind are largely positive and generate an exchange of experience that benefits both sectors. However, transitions from employment in the public sector to the private sector can give rise to what is known as the revolving door problem. This
The Swedish age of criminal responsibility means that children under 15 who commit offences cannot be sentenced to any penalty. There is, however, a process in § 38 LUL that can determine whether a child under 15 has commit-ted a serious crime, called an evidentiary proceeding. At the time of its crea-tion, the purpose of an evidentiary proceeding was to provide the child wel-fare authorities with
On the first of July 2018, Sweden made a drastic change to its rape provision, by adopting a new legislation, commonly referred to as the ”Consent Law”. Sweden’s neighboring country, Denmark, adopted its own version of the Consent Law a couple of years later, on the first of January 2021. The newely change of the Swedish and Danish penal codes have been an important step torwards reducing rap
The new Market Abuse Regulation (the MAR) entered into force on July 3rd 2016. The MAR is the latest step in a long-running regulatory process from the EU concerning the securities market, and as it entered into force it replaced the previously applicable Market Abuse Directive (the MAD). The MAR contains a few novelties, which can appear alien to Swedish operators at the securities market. For ex
The Market Abuse Regulation (MAR) came into force on 3 July 2016 and replaced the previous Market Abuse Directive (MAD). Among the obligations regulated by MAR, there is a duty for the issuer to publish inside information. According to article 17 (1) MAR, the issuer is obligated to inform the public concerning inside information directly affecting the issuer as soon as possible. The issuer must al
On 8 July 2019, ICC Trial Chamber VI found Congolese commander Bosco Ntaganda guilty for rape as a crime against humanity. In March 2021, the appealed verdict was upheld by the Appeals Chamber of the ICC, making it the first conviction in history to sentence someone as individually criminally responsible for rape as a crime against humanity. Sexual violence in armed conflicts has been a highly to
