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Animals across phyla can detect early cues of infection in conspecifics, thereby reducing risk of contamination. It is unknown, however, if humans can detect cues of sickness in people belonging to communities with whom they have limited or no experience. To test this, we presented Western faces photographed two hours after the experimental induction of an acute immune response to one Western and
Aquaglyceroporins are channels that facilitate the flux of glycerol and water across lipid bilayers. Although structural information is available for several aquaglyceroporins, the details of how water and glycerol selectivity are maintained and how protons are excluded remain elusive. An approach to obtaining data on the hydrogen atom positions is to apply neutron macromolecular crystallography.
BRCA1-associated protein 1 (BAP1) is a nuclear deubiquitinating enzyme that is associated with multiprotein complexes that regulate key cellular pathways, including cell cycle, cellular differentiation, cell death, and the DNA damage response. In this study, we found that the reduced expression of BAP1 pro6motes the survival of neuroblastoma cells, and restoring the levels of BAP1 in these cells f
After the latest Permian mass extinction event, microbial mats filled the ecological niche previously occupied by metazoan reefs, resulting in widespread microbialites. This study focuses on the lipid biomarker (molecular fossil) and invertebrate fossil records from Neotethyan platform margin sections to understand microbial-metazoan bioherm formation. Here, we find that early Griesbachian thrombo
Background: The Bethesda system for cytopathology (TBSRTC) is a 6-tier diagnostic framework developed to standardize thyroid cytopathology reporting. The aim of this study was to determine the risk of malignancy (ROM) for each Bethesda category. Methods: Thyroidectomy-related data from 314 facilities in 22 countries were entered into the following outcome registries: CESQIP (North America), Eurocr
Chronic obstructive pulmonary disease (COPD) is a leading cause of death world-wide. Recently, we showed that COPD is associated with gene polymorphisms in SUMF1, a master regulator of sulfatases. Sulfatases are involved in extracellular matrix remodeling and activated by SUMF1, but their role in the lung is poorly described. We aimed to examine how sulfatases are affected in the airways of patien
Subjective reports of sleep disturbance are a common feature of Huntington's disease (HD); however, there is limited research investigating the relationship between sleep problems with changes in brain and behaviour. This study aimed to investigate whether subjective reports of sleep problems in HD are associated with brain volume, neurocognitive decline, and neuropsychiatric symptoms. This retros
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To determine the benefits and harms associated with weight loss in overweight individuals with knee or hip osteoarthritis in terms of pain, physical function, quality of life, and safety. Further we will have an explicit focus on quality of the weight loss intervention (including magnitude and intensity) (Herbe
I denna uppsats appliceras Fama-Frenchs femfaktormodell på den svenska aktiemarknaden och jag undersöker om det går att ge stöd för att en utökning med en eller två faktorer till Fama-Frenchs trefaktormodell förbättrar förklaringsförmågan till variationen i aktieavkastning. Fama & French (1993) visar att en modell bestående av tre faktorer - marknadsfaktorn, storleksfaktorn och värdefaktorn -
Since the Council Directive (EU) 2016/1164 of 12 July 2016 laying down rules against tax avoidance practices that directly affect the functioning of the internal market (ATAD) and its anti-tax avoidance rules entered into force, the national tax authorities and courts face the task of interpreting and applying national anti-tax avoidance measures in conformity with the directive. However, in the c
The new bill “violation of a child’s integrity” went into force on the 1st of July, 2021 to ensure that more rights for children in criminal law were implemented. The bill was placed in chapter 4 section 3 in the Swedish Criminal Code (1962:700). In the section there is a line up of an exhaustive list of foundation crimes. In order for the violation of a child’s integrity to be able to come into e
Herbivory is an important part of most ecosystems and affects the ecosystems' carbon balance both directly and indirectly. Little is known about herbivory and its impact on the carbon balance in high arctic mire ecosystems. We hypothesized that trampling and grazing by large herbivores influences the vegetation density and composition and thereby also the carbon balance. In 2010, we established fe
I denna studie undersöks kampanjen Nationer mot narkotika. Med utgångspunkt i teorier om narratologi är syftet med uppsatsen att få en ökad förståelse för hur en antidrogkampanj kan säga något om sändarens intentioner, samt granska vilken roll sändaren kan komma att ha i kampanjens framgång. Studiens analysmaterial grundar sig i en kvalitativ metod med tre stycken semistrukturerade intervjuer. Stu
Sexual consent has been discussed for many years. On July 1, 2018, the so-called ”consent law” was introduced into Swedish law. The essay deals with this legislation and how it can make a difference in sexual offense cases where intentions have not been proven. The focus is on relationships where dominance and submissiveness is a lifestyle, or at least one element. Cases will be reported and analy
Ternary semiconductor nanowire arrays enable scalable fabrication of nano-optoelectronic devices with tunable bandgap. However, the lack of insight into the effects of the incorporation of Vy element results in lack of control on the growth of ternary III-V1-yVy nanowires and hinders the development of high-performance nanowire devices based on such ternaries. Here, we report on the origins of Sb-
Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying factor (SUMF1) is a key modifier in connective tissue remodelling, and we have shown previously that several SNPs in SUMF1 are associated with COPD. The aim of this study was to investigate the association between SUMF1 SNPs and advanced
Background: Rheumatoid arthritis (RA) poses a significant health burden, with patients facing a twofold higher risk of cardiovascular diseases compared to the general population. As a results, the international recommendations set forth by the European Alliance of Associations for Rheumatology, advocate for a structured cardiovascular (CV) risk management and adherence to a healthy lifestyle for p
