The present multidisciplinary study examined nigrostriatal dopamine and striatal amino acid transmission in the R6/1 line of transgenic Huntington's disease (HD) mice expressing exon 1 of the HD gene with 115 CAG repeats. Although the number of tyrosine hydroxylase-positive neurons was not reduced and nigrostriatal connectivity remained intact in 16-week-old R6/1 mice, the size of tyrosine hydroxy

We used the open-channel blocker, penicillin (10 mM), as a tool to investigate if the human α1β1 or α1β1γ2S γ-aminobutyric acid type A (GABAA) receptor channels opened in the absence of GABA. Application of penicillin to cells expressing the receptors resulted in a transient inward whole-cell current, the off-current, upon penicillin removal. The amplitude of the off-current was dependent on the d

We recently reported that HIV-1 infection can be inhibited by innate antimicrobial components of human seminal plasma (SP). Conversely, naturally occurring peptidic fragments from the SP-derived prostatic acid phosphatase ( PAP) have been reported to form amyloid fibrils called "SEVI'' and enhance HIV-1 infection in vitro. In order to understand the biological consequence of this proviral effect,

Popular Abstract in Swedish Leukemi kännetecknas av en okontrollerad tillväxt av omogna vita blodkroppar och orsakas av förvärvade genetiska förändringar. Genetiska förändringar eller avvikelser, som är drivande i cancerutvecklingen, uppstår när normala celler delar sig. Identifiering av sådana förändringar på gen-och kromosomnivå är av stor klinisk betydelse. Behandling styrs av vilka genetiska aAcute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children 50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. In contrast to pediatric ALL, which has a favorable prognosis, adult ALL is associated with a much poorer outcome with less than 40% overall survival rates, decre

In recent years, dynamical modelling has been provided with a range of breakthrough methods to perform exact Bayesian inference. However, it is often computationally unfeasible to apply exact statistical methodologies in the context of large data sets and complex models. This paper considers a nonlinear stochastic differential equation model observed with correlated measurement errors and an appli

Purpose: Physical activity level is a prognostic variable for patients with injuries. Self-report questionnaires exist to obtain these measures; however, they are not accessible to all populations because of language barriers. Therefore, the purpose of this study was to translate and validate the Hospital for Special Surgery Pediatric Functional Activity Brief Scale (HSS Pedi-FABS) for francophone

Background and Objectives Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The extent to which these biomarkersmay outperformone another in predicting future Alzheimer dementia diagnosis is poorly understood, however. This study investigated 2 specific AD biomarkers, i.e., a cortic

Antiglomerular basement membrane (GBM) disease is known as a super-acute proliferative glomerulonephritis caused by auto-antibodies targeting the NC1 domain of the α3 chain of type IV collagen.Here, we describe a case of atypical anti-GBM disease presenting as a dialysis-dependent acute renal failure with unusual mild glomerular involvement. We found that immunoglobulin G (IgG) deposits were restr

Microsoft Word - HILMA 2007-06-21.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 32, 2006/07, Nr 13, 2007-06-21 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_vt07_07.pdf - 2025-07-07

Avdelningschef Magnus Svensson Avdelningschef E-post: magnus [dot] svensson [at] jur [dot] lu [dot] se Telefon: +46 46 222 10 20 Mer information om Magnus Svensson Medarbetare John Andersson Amanuens E-post: john [dot] andersson [at] jur [dot] lu [dot] se Telefon: +46 46 222 11 26 Mer information om John Andersson Sofia Andersson Amanuens E-post: sofia [dot] andersson [at] jur [dot] lu [dot] se Te

https://www.jur.lu.se/kontakt/avdelningen-distans-och-uppdragsutbildning-samt-e-larande - 2025-07-08

Brevmall Postadress Box 117, 221 00 Lund Besöksadress Kemicentrum, Sölvegatan 39B, Telefon 046-222 9399, 046-222 00 00, E-post Kjell.Josefsson@fs.lu.se Rektor Samfinansiering av indirekta kostnader för forskningsbidrag från National Institutes of Health Bakgrund Universitetet deltar i flera forskningsprojekt finansierade med amerikanska statliga medel, varav den största andelen kommer från Nationa

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/samfinansiering-av-indirekta-kostnader-for-forskningsbidrag-fran-national-institutes-of-health.pdf - 2025-07-09

NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 20 v 22 - 2021. UNIVERSITETSGEMENSAMT Lönerevisionen drar ut på tiden Förhandlingarna med anledning av lönerevisionen pågår fortfarande. Tyvärr kan det konstateras att det nu har dragit ut så långt i tiden at

https://www.cec.lu.se/sites/cec.lu.se/files/2021-06/LU-gemensamt%20Mejlutskick%20Nr%2020-v22-2021.pdf - 2025-07-09

FOLDER 3 Universitetsbibliotekets utställningskatalog 60 28 Universitetsbiblioteket, Lunds universitet Box 3, 221 00 LUND UB Media. ISSN 0281-3823, LULID/LIBR - 1548 4 februari - 22 maj 2011 Brevsamlingen Vänskapen och kontakten mellan den svenske konstnären och författaren Gösta Adrian-Nilsson (GAN, 1884-1965) och den danske surrealistiske konstnären Wilhelm Freddie (1909-1995) har hittills varit

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2011_hello_freddie.pdf - 2025-07-09

Brottsofferfrågor är ofta rättspolitiskt laddade och komplexa. Efter terrordådet på Drottninggatan i Stockholm 2017 aktualiserades frågan om Sverige lever upp till EU:s terrorismdirektiv om skydd av, stöd till och rättigheter för offer för terrorism. Tidigare har Brottsoffermyndigheten dragit av 1500 kronor på det belopp som fastställs vara skäligt och som ska ge brottsoffret kompensation för det

1 M al m ö A rt A ca de m y 20 17 – 20 18 Masters of Fine Arts – Year 1 Masters of Fine Arts – Critical & Pedagogical Studies – Year 1 Bachelor of Fine Arts – Year 2 Bachelor of Fine Arts – Year 1 2M al m ö A rt A ca de m y M al m ö A rt A ca de m y 20 17  –  2 01 8 20 17  –  2 01 8 20 17  –  2 01 8 3 Andreas Bentdal Amble Rannveig Jónsdóttir Carl-Oskar Jonsson Cecilia Kanthi Jonsson Gabriel Karls

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/yearbook2_2018.pdf - 2025-07-09

LL_KSMD44_VT21_beslut_201014 Litteraturlista för Handel och hållbarhet (KSMD44), 15 hp Litteraturlistan är fastställd av styrelsen för institutionen för styrelsen för service management och tjänstevetenskap 2020-10-14. Litteraturlistan börjar gälla den 2021-01-18. Alvehus, Johan. (2018). Problemformulering. Lund: Studentlitteratur. [112 sidor, ISBN 978-91- 441192-8-1] Alvehus, Johan. (2019). Skriv

https://www.ses.lu.se/sites/ses.lu.se/files/ll_ksmd44_vt21_beslut_201014.pdf - 2025-07-09

The crystal structure of the flavodoxin-like protein WrbA with oxidized FMN bound reveals a close relationship to mammalian NAD(P) H:quinone oxidoreductase, Nqo1. Structural comparison of WrbA, flavodoxin, and Nqo1 indicates how the twisted open-sheet fold of flavodoxins is elaborated to form multimers that extend catalytic function from one-electron transfer between protein partners using FMN to

We report the first large series (n=596) of pediatric acute myeloid leukemia (AML) focusing on modal numbers (MN) from the population-based NOPHO-AML trials. Abnormal karyotypes were present in 452 cases (76%) and numerical aberrations were present in 40% (n=237) of all pediatric AML. Among patients with an abnormal karyotype, the MN 46 was most common (n=251; 56%) of which 36 (8%) were pseudodipl

The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which l