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Hydrogels are a hydrophilic network of polymers (usually cross-linked polysaccharides) that are natural or synthetic. Applications of hydrogels are many in the biomedical field. Because of the high water absorption (10 to 200 grams of water per gram of hydrogel), hydrogels have a high degree of flexibility similar to natural human tissue. Human cells can be incorporated into the hydrogel, which in

Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). Knowledge of the incidence, risk factors, and the underlying mechanisms of AB induced by AEDs may help to facilitate management and reduce the risk of such side effects. The exact incidence of AB as an adverse e

The present study concerns the application of a large eddy simulation (LES) model, capable of dealing with chemical reactions described by multistep reaction mechanisms and thermal radiation. The LES model, based on prefiltering of the balance equations of mass, momentum, and energy contains a variety of submodels far representing the residual stress tensor and flux vectors and the filtered reacti

Popular Abstract in Swedish Atomer är de grundläggande byggstenarna för alla material runt omkring oss. Varje enskild atom består av ett tätt packat område i centrum, som kallas atomkärnan, omgivet av ett moln av elektroner. Atomkärnan innehåller neutroner och protoner, hopbundna av den starka kärnkraften. Vissa kombinationer av neutroner och protoner leder till bildandet av kärnor som är stabila

The galectins are known to be able to recognize and cross-link beta-D-galactopyranoside-containing glycoconjugates as a result of presenting multiple binding sites. This review summarizes efforts in our group for the last ten years towards low-molecular weight chemically modified carbohydrate derivatives. In addition to providing an avenue for improved affinity and galectin-selectivity, we have fo

Oxidative-addition of PhTe2Ph to the furyne cluster [Ru-3(CO)(7)(mu-H)(mu(3)-eta(2)-C4H2O){mu-P(C4H3O)(2)}(mu-dppm)] (1) results in the isolation of four complexes; (i) the previously reported 54-electron cluster [Ru-3(CO)(6)(mu(3)-Te)(2)(mu-TePh)(2)(mu-dppm)] (5) which results from elimination of trifuryl phosphine, (ii) the furenyl cluster [Ru-3(CO)(5)(mu-eta(2)-C4H3O){mu-P(C4H3O)(2)}(mu-TePh)(2

Submerged sea grasses and stoneworts growing in the immediate nearshore of the Baltic Sea are sensitive indicators of sea level. The alternating changes in concentrations of sea grass and stonewort macrofossils, obtained from an ancient lagoon of the Baltic Sea, are ascribed to middle Holocene sea-level fluctuations along the southeastern Swedish coast. Abundances of stonewort and sea grass macrof

The European Summer School in Logic, Language and Information (ESSLLI) is organized every year by the Association for Logic, Language and Information (FoLLI) in different sites around Europe. The main focus of ESSLLI is on the interface between linguistics, logic and computation. ESSLLI offers foundational, introductory and advanced courses, as well as workshops, covering a wide variety of topics

Introduction: The molecular mechanics energies combined with the Poisson-Boltzmann or generalized Born and surface area continuum solvation (MM/PBSA and MM/GBSA) methods are popular approaches to estimate the free energy of the binding of small ligands to biological macromolecules. They are typically based on molecular dynamics simulations of the receptor-ligand complex and are therefore intermedi