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Background: Intracoronary physiology is increasingly used in nonculprit stenoses of patients with acute coronary syndromes (ACS). However, evidence regarding the safety of fractional flow reserve-based deferral in patients with ACS, compared with patients with stable angina pectoris (SAP), is scarce. Objectives: The aim of this study was to evaluate the safety of revascularization deferral on the
Fuel cells, redox flow batteries and some water desalination technologies such as reverse osmosis and electrodialysis require efficient ion exchange membranes to perform in an optimum way. Thus, by enhancing the properties of these membranes there is a possibility to improve this type of applications and technologies. Depending on the specific application, anion or proton exchange membranes with g
INTRODUCTION: Previous studies have shown an increased risk of obstetric complications in pregnancies after oocyte donation (OD). The present study includes all singletons born after OD during 10 years in Sweden.MATERIAL AND METHODS: A retrospective cohort study that included data from all Swedish in vitro fertilization (IVF) clinics between 2003 and 2012 was performed. Data were cross-linked with
Industrial biotechnology has been defined as the use and application of biotechnology for the sustainable processing and production of chemicals, materials and fuels. It makes use of biocatalysts such as microbial communities, whole-cell microorganisms or purified enzymes. Although biocatalysts are considered advantageous, since they operate under mild conditions regarding temperature and pH and e
Background: Lewy body Dementia (LBD) is a well-known neurocognitive disorder in the elderly. The hallmarks of LBD are Parkinsonism without tremor, recurrent and persistent visual hallucinations often with insight, fluctuating cognition and alertness, rapid eye movement (REM) sleep behavior disorder with vivid dreams and violent movements, but relatively preserved memory functions. Nevertheless, LB
OBJECTIVES: Preterm birth has been linked with increased risk of autism spectrum disorder (ASD); however, potential causality, sex-specific differences, and association with early term birth are unclear. We examined whether preterm and early term birth are associated with ASD in a large population-based cohort. METHODS: A national cohort study was conducted of all 4 061 795 singleton infants born
Rationale: Evidence suggests that continuous positive airway pressure (CPAP) treatment promotes weight gain in patients with obstructive sleep apnea (OSA). It is unclear whether weight gain is influenced by CPAP adherence or comorbid disorders. Objectives: To examine the CPAP effects on body mass index (BMI) and local adiposity and the potential moderators of CPAP effects on BMI in patients with O
Background: Opioid-based treatment is used to manage stress responses during surgery and postoperative pain. However, opioids have both acute and long-term side effects, calling for opioid-free anaesthetic strategies. This meta-analysis compares adverse events, postoperative recovery, discharge time from post-anaesthesia care unit, and postoperative pain, nausea, vomiting, and opioid consumption b
Quality of Life and long-term clinical outcome following robot-assisted radical trachelectomy. Objectives: To evaluate quality of life (QoL) and long-term clinical outcome following robot-assisted radical trachelectomy (RRT). Study Design: Prospectively retrieved clinical data were rereviewed on all women planned for a fertility sparing RRT for early stage cervical cancer at Skåne University Hospi
Background: Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes of exenteration over time.Methods: This was a multicentre retrospective study of patients who underwent exenteration for LARC and LRRC between 2004 and 2015. Su
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors
Purpose: To describe the use of assistive devices and postural asymmetries in lying, sitting and standing positions in adults with cerebral palsy, and to analyze postural asymmetries and any associations with their ability to maintain or change position and time in these positions. Methods: A cross-sectional study based on data from the Swedish Cerebral Palsy follow-up program of 1,547 adults aged
Climate change substantially affects plant phenology, resulting in earlier vegetation onset across temperate and boreal regions. Phenological shifts caused by warming may alter species interactions across trophic levels because of species-specific responses, and influence the reproductive success of dioecious species if the phenological sensitivity to warming (ST) differs between genders. We used
Objective:To assess cardiovascular effects of in-utero HIV and antiretroviral treatment (ART) exposure on offspring of HIV-positive mothers in Ethiopia.Design:HIV-positive and HIV-negative pregnancies were identified from a prospective cohort of women recruited at their first antenatal care visit in Ethiopia, using a nested case-control design.Methods:Fetal standard ultrasound and echocardiography
Background: Previously, we investigated tonsillar carriage of Fusobacterium necrophorum by PCR and found a high tonsillar carriage rate (21%) in asymptomatic 15-25year olds, but the same age group is most commonly affected by severe F. necrophorum infections. Interestingly, we found Cycle threshold (Ct)-values in asymptomaticcarriers to be high (median 29). Possibly, the Ct-value could differentia
Background: Previously, we investigated tonsillar carriage of Fusobacterium necrophorum by PCR and found a high tonsillar carriage rate (21%) in asymptomatic 15-25 year olds, but the same age group is most commonly affected by severe F. necrophorum infections. Interestingly, we found Cycle threshold (Ct)-values in asymptomatic carriers to be high (median 29). Possibly, the Ct-value could different
Objective To investigate the admission rate to neonatal care and neonatal morbidity after maternal use of antipsychotics during pregnancy. Design A population-based register study. Setting Information on all singleton births between July 2006 and December 2017 in Sweden including data on prescription drugs, deliveries and infants' health was obtained from the Swedish Medical Birth Register, the Pr
BackgroundHIV-associated infective native aortic aneurysms (INAA) constitute a subcategory of the disease INAA. This is a very rare group of patients.ObjectivesThe aim of this systematic literature review was to compile a description of patient characteristics with HIV-associated INAA.MethodsA systematic literature review was performed using the search terms HIV and aortic aneurysm in Ovid MEDLINE
Purpose: The need for sentinel lymph node biopsy (SLNB) in clinically node-negative (cN0) patients is currently questioned. Our objective was to investigate the cost-effectiveness of a preoperative noninvasive lymph node staging (NILS) model (an artificial neural network model) for predicting pathological nodal status in patients with cN0 breast cancer (BC). Methods: A health-economic decision-ana
