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Long-term ambient air pollution exposure and renal function and biomarkers of renal disease

Background: Despite accumulating evidence of an association between air pollution and renal disease, studies on the association between long-term exposure to air pollution and renal function are still contradictory. This study aimed to investigate this association in a large population with relatively low exposure and with improved estimation of renal function as well as renal injury biomarkers. M

Characterization of the Combustion of Light Alcohols in CI Engines : Performance, Combustion Characteristics and Emissions

Alternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local cAlternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local c

High dose-per-pulse electron beam dosimetry : Usability and dose-rate independence of EBT3 Gafchromic films: Usability

Purpose: The aim of this study was to assess the suitability of Gafchromic EBT3 films for reference dose measurements in the beam of a prototype high dose-per-pulse linear accelerator (linac), capable of delivering electron beams with a mean dose-rate (Dm) ranging from 0.07 to 3000 Gy/s and a dose-rate in pulse (Dp) of up to 8 × 106 Gy/s. To do this, we evaluated the overall uncertainties in EBT3

Determinants of sports injury in young female Swedish competitive figure skaters

Introduction: Although figure skating attracts several hundred thousand participants worldwide, there is little knowledge about physical health and sports injuries among young skaters. The present study aimed to describe the health status of a geographically defined Swedish population of licensed competitive figure skaters and to examine injury determinants. Methods: All licensed competitive skat

Prevalence of Subclinical Coronary Artery Atherosclerosis in the General Population

BACKGROUND: Early detection of coronary atherosclerosis using coronary computed tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA to determine the prevalence, severity, and characteristics of coronary atherosclerosis and its association with CAC scores in a general population.METHODS: We recruited 30 154 r

Poor adult tuberculosis treatment outcome and associated factors in Gibe Woreda, Southern Ethiopia : An institution-based cross-sectional study

Tuberculosis (TB) remains a major medical and public health problem throughout the world, especially in developing countries including Ethiopia. Its control program is currently being challenged by the spread of drug-resistant TB, which is the result of poor treatment outcomes. Hence, this study assessed poor adult TB treatment outcomes and associated factors in Gibe Woreda, Southern Ethiopia. An

Temporal changes in the probability of live birth among female survivors of childhood cancer : A population-based Adult Life After Childhood Cancer in Scandinavia (ALiCCS) study in five nordic countries

BACKGROUND: During the past 4 decades, there has been a growing focus on preserving the fertility of patients with childhood cancer; however, no large studies have been conducted of live births across treatment decades during this period. Therefore, the authors estimated the potential birth deficit in female childhood cancer survivors and the probability of live births. METHODS: In total, 8886 wom

Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D

BACKGROUND: The purpose of this study was to estimate precise age-specific tubo-ovarian carcinoma (TOC) and breast cancer (BC) risks for carriers of pathogenic variants in RAD51C and RAD51D. METHODS: We analyzed data from 6178 families, 125 with pathogenic variants in RAD51C, and 6690 families, 60 with pathogenic variants in RAD51D. TOC and BC relative and cumulative risks were estimated using com

Higher long-term cardiovascular morbidity after open surgery for intermittent claudication caused by infrainguinal atherosclerotic disease in patients with diabetes - A nationwide observational cohort study

Summary: Background: Diabetes mellitus (DM) is a risk factor for peripheral arterial disease (PAD). Indications for open surgery in infrainguinal intermittent claudication (IC) are limited, and reports are lacking regarding outcomes in DM patients. Study aims were to compare short and long-term effects on major adverse cardiovascular events (MACE), acute myocardial infarction (AMI), stroke, major

Evaluation of Circulating Cardiovascular Biomarker Levels for Early Detection of Congenital Heart Disease in Newborns in Sweden

Importance: Congenital heart disease (CHD) is the most common congenital malformation in humans worldwide. Circulating cardiovascular biomarkers could potentially improve the early detection of CHD, even in asymptomatic newborns. Objectives: To assess the performance of a dried blood spot (DBS) test to measure the cardiovascular biomarker amino terminal fragment of the prohormone brain-type natriu

Cervical cancer prevention among long-term screening non-attendees by vaginal self-collected samples for hr-HPV mRNA detection

Background: The efficacy of cervical cancer screening programs is dependent on the participation rate. To increase participation among women not attending cervical cancer screening, self-collected samples for detection of high-risk human papillomavirus (hr-HPV) may be an option. The aims of this study were: to investigate the response rate to sending a self-collected vaginal sample for hr-HPV mRNA

The use of a Peer Assisted Study Scheme to help the transition from Secondary school to Higher Education

This presentation will give an overview of a peer learning model called Supplemental Instruction - Peer Assisted Study Scheme (SI-PASS). SI-PASS was invented at the University of Missouri in Kansas City, USA in the early1970s and was then directed to Universities and for the university students. In this presentation, the focus and discussion will be on how SI-PASS can be implemented in secondary s

Academic Support using Peer Assisted Study Schemes (SI-PASS) to help new students with the transition to Higher Education. A European overview.

This presentation gives an overview of a peer learning model and academic support intervention named SI-PASS (Supplemental Instruction – Peer Assisted Study Schemes) in Higher Education in Europe. SI-PASS is a method of improving student performance in “difficult”, normally introductory, courses combining “how to learn” with “what to learn”. SI-PASS sessions are scheduled parallel to the regular e

Delays and Timetabling for Passenger Trains

Resandet med tåg har ökat stadigt i Sverige de senaste 30 åren. Takten har varit cirka två-tre procent per år, och vi nu har mer än dubbelt så många resenärer. Med ökat fokus på klimatfrågan stiger resandet nu ännu snabbare. Ett problem som drabbar både resenärer och företag i Sverige är tågförseningar. Ett sätt att beskriva dessa är den andel av alla tåg som kommer fram mer än fem minuter för senTravel by train has increased steadily in Sweden the last 30 years. The pace has been about two to three percent per year, and we now have twice as many passengers. With growing awareness of the changing climate, the pace is increasing further. A problem that affects both passengers and businesses in Sweden is train delays. One way to describe these is as the share of trains that arrive less than

Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes : the TEDDY study

BACKGROUND: Participants' study satisfaction is important for both compliance with study protocols and retention, but research on parent study satisfaction is rare. This study sought to identify factors associated with parent study satisfaction in The Environmental Determinants of Diabetes in the Young (TEDDY) study, a longitudinal, multinational (US, Finland, Germany, Sweden) study of children at

Sample preparation effect on measured rheological properties of bitumen using Dynamic Shear Rheometer

Through improved bitumen characterization, which will increase the road'sdurability, stability, and performance, pavement engineering can apply thesustainability notion that should be followed in all disciplines nowadays. The newtechniques distinguish between the rheological properties of bituminous binders as a function of loading time and temperature to depict real-world behavior rather than onl

Measurement report : Black carbon properties and concentrations in southern Sweden urban and rural air-the importance of long-range transport

Soot, or black carbon (BC), aerosol is a major climate forcer with severe health effects. The impacts depend strongly on particle number concentration, size and mixing state. This work reports on two field campaigns at nearby urban and rural sites, 65gkm apart, in southern Sweden during late summer 2018. BC was measured using a single-particle soot photometer (SP2) and Aethalometers (AE33). Differ

Pain and function in patients with chronic low back pain and leg pain after Zhineng Qigong : a quasi-experimental feasibility study

BACKGROUND: Qigong includes training for body and mind, one method is Zhineng Qigong. Scientific literature on qigong for chronic low back pain (LBP) is sparse. This study aimed to investigate feasibility including evaluation of a Zhineng Qigong intervention for pain and other lumbar spine-related symptoms, disability, and health-related quality of life in patients with chronic LBP and/or leg pain

Importance of tumor volume, overall treatment time and fractionation sensitivity for p16-positive and p16-negative oropharyngeal tumors

BACKGROUND: Analyses of clinical outcomes following radiotherapy (RT) have advanced our understanding of fundamental radiobiological characteristics in head and neck squamous cell carcinoma (HNSCC). Low fractionation sensitivity appears to be a common feature, as well as susceptibility to changes in overall treatment time (OTT). Large tumors should be harder to cure if a successful RT requires the

Outcomes After Endovascular Aortic Intervention in Patients With Connective Tissue Disease

Importance: Endovascular treatment is not recommended for aortic pathologies in patients with connective tissue diseases (CTDs) other than in redo operations and as bridging procedures in emergencies. However, recent developments in endovascular technology may challenge this dogma. Objective: To assess the midterm outcomes of endovascular aortic repair in patients with CTD. Design, Setting, and Pa