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Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children in the western world. HUS is characterized by the triad of hemolytic anemia, thrombocytopenia and renal failure. There are two main subtypes of HUS; typical or D+ (D stands for diarrhea) HUS associated with enterohemorrhagic E. coli (EHEC) infection, which accounts for about 90% of all HUS cases, and atypic
In this study, we first determined the low molecular weight dissolved organic carbon (LMW DOC) concentration-dependent kinetics of soil respiration in a temperate grassland soil sampled on successive occasions. We then used the established relationship to estimate in situ LMW DOC concentrations from basal respiration measurements. C-14-labelled glucose was used as a model substrate and was added t
Background: Epidemiological studies on the association between maternal exposure to persistent organic pollutants (POPs) and fetal growth alteration report inconsistent findings which weights in favor of additional studies. Methods: Blood samples were collected from interviewed pregnant women in Greenland (572), Kharkiv (611) and Warsaw (258) and were analyzed for CB-153 and p,p'-DDE by gas chroma
The available energy (AE), driving the turbulent fluxes of sensible heat and latent heat at the earth surface, was estimated at four partly complex coniferous forest sites across Europe (Tharandt, Germany; Ritten/Renon, Italy; Wetzstein, Germany; Norunda, Sweden). Existing data of net radiation were used as well as storage change rates calculated from temperature and humidity measurements to final
Introduction Colon cancer is one of the most common forms of cancer world wide, with an incidence of almost 1 million cases anually. Surgery is a prerequisite for cure and the majority of patients are potentially curable at diagnosis. For a surgical resection to be curative the surgeon needs to remove the tumour together with all affected regional lymph nodes. How extensive the mesenteric resecti
Introduction The incidence of perforated peptic ulcer remains high in low and middle-income countries. Mortality can be significant, and early surgical management with careful evaluation of pre-operative risk factors is essential. The purpose of this study was to describe the clinical outcomes of surgical treatment for perforated peptic ulcer disease in Liberia and to explore risk factors for adve
PURPOSE: The purpose of this study was to report an initial experience with the endovascular repair of descending thoracic aortic aneurysm. Complications and intermediate-term morphologic changes were identified with the intent of altering patient selection and device design. METHODS: Endografts were placed into 25 patients at high-risk for conventional surgical repair over a 3(1/2)-year period. D
OBJECTIVE: To evaluate newly developed equations predicting relative glomerular filtration rate(GFR) in adult Swedish Caucasians and to compare with the Modification of Diet in Renal Disease(MDRD) and Mayo Clinic equations using enzymatic and zero-calibrated plasma creatinine assays. MATERIAL AND METHODS: GFR was measured with iohexol clearance adjusted to 1.73 m(2). One population sample (n=436/L
The prognostic impact of body mass index ( BMI) in patients following acute myocardial infarction ( AMI) may be altered by neurohormonal blockade. Methods: The impact of neurohormonal blockade on the association between BMI and mortality was examined in 5548 patients following AMI ( CONSENSUS II), 50% receiving enalapril and 7% beta- blockade, and in 4367 patients with coronary artery disease ( CA
The purpose of this study was to characterize the emissions of a large number of chemical compounds emitted from birch wood combustion in a wood stove. Birch wood is widely used as fuel in Swedish household appliances. The fuel load was held constant during six experiments. Particles < 2.5 mum diameter were collected and the size distribution of the particles was measured. The results were compare
OBJECTIVE: To investigate the risk of asthma in hairdressers. METHODS: The incidence of asthma was retrospectively estimated in a Swedish nationwide study including all female hairdressers certified from vocational schools from 1970 to 1995, and a stratified sample of women from the general population were referents. A postal questionnaire included questions on respiratory tract symptoms, atopy, s
Sulfur-containing compounds are used as rescue agents to protect normal tissue from the toxic side effects of cis-[PtCl2(NH3)(2)] (cisplatin) without affecting its anti-tumour activity. Reactions of the model complexes [Pt(dien)Cl](+) (1) and [Pt(dien)(GSMe)](2+) (2) (GSMe = S-methylglutathione) with the rescue agents glutathione (GSH), thiourea, thiosulfate, and diethyldithiocarbamate (DDTC) have
The importance of colonic fermentation has been realised during recent years as it has been found to be associated with colonic health and thus the overall health of the individual. The fermentation of dietary fibre and the addition of probiotics can have positive effects on the luminal environment and the colonic microbiota. Short-chain fatty acids, formed by the fermentation of dietary fibre, ha
Popular Abstract in Swedish Akut pankreatit (bukspottkörtelinflammation) drabbar årligen cirka 300 individer per miljon invånare i Sverige. Dödligheten ligger totalt på cirka 4-7 % och betydligt högre, cirka 20 %, vid svår nekrotiserande pankreatit. Mortaliteten är vanligen associerad med multipel organsvikt och korrelerad till storleken på det inflammatoriska svaret. Underliggande mekanismer för Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating ev
The increasingly apparent environmental problems in our surroundings necessitate a quest for sustainable development in all areas of human endeavour. Within the field of chemistry and the production of chemicals, the focus is increasingly on the development of green chemistry. This discipline aims to reduce environmental impact by replacing petrochemical raw materials with renewable feedstock and
AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine-phosphate-guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through which single-nucleotide polymorphisms (SNPs) can affect gene function via epigenetics. The aim of this
Background: High plasma copeptin (copeptin), the C-terminal fragment of arginine vasopressin pro-hormone, has been associated with the metabolic syndrome (MetS), diabetes mellitus (DM) development and nephropathy. Here we tested whether elevated copeptin level is associated with later development of the MetS, its individual components and microalbuminuria. Methods: We analysed copeptin at baselin
BACKGROUND: Situational needs of health care facilities inform the optimal allocation of resources and quality improvement efforts. This study examines surgical care delivery metrics at a tertiary care institution in Liberia. METHODS: We retrospectively reviewed operative and ward logbooks from January 1 to December 31, 2012. Data parameters included patients' age, diagnosis, procedure, mortality,
Objectives: First, to outline the theoretical and practical framework for geriatric rehabilitation in the Nordic countries and second, to survey the scientific medical publications for evidence-based geriatric rehabilitation. Methods: Brainstorming on geriatric rehabilitation in a working group of Nordic teachers in geriatric medicine. Papers on scientific programmes for geriatric rehabilitation f
Male breast cancer is poorly understood with a large proportion arising in the familial context particularly with the BRCA2 germline mutation. As phenotypic and genotypic differences between sporadic and familial male breast cancers have been noted, we investigated the importance of a hypoxic drive in these cancers as this pathway has been shown to be of importance in familial female breast cancer
