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Large real-world registry data are important for understanding the current use and outcomes of novel therapies. The aim of this study was to assess treatment patterns and outcomes in patients who underwent percutaneous coronary intervention (PCI) with prasugrel or clopidogrel. Consecutive patient data from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) for 2010 and 2011 were use
Objectives The aim of this study was to describe the characteristics and outcome of all consecutive patients treated with percutaneous coronary intervention (PCI) in an unselected nationwide cohort over the past 2 decades. Background Over the last 20 years, treatment with PCI has evolved dramatically, but the change in patient characteristics has not been well described. Methods We included all pa
This non-interventional post-authorisation safety study (PASS) assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC) who participated in the TuberOus SClerosis registry to increase disease Awareness (TOSCA) clinical study and received everolimus for the licensed indications in the European Union. The rate of adverse events (AEs), AEs that led to dose adjustm
The purpose of this study is to interogate the tension-laden relationsship between men (of the dominant classes and ethnicities) and feminism. Closely linked to this lies the question of how valid and relevant official Swedish goals of gender equality can be to the Centres for Women´s Studies and Gender Research in Sweden. The essay is mainly an in-depth qualitative study concerned about question
Background: Brief episodes of atrial fibrillation (AF) may evolve into longer AF episodes increasing the chances of thrombus formation, stroke, and death. Classical methods for AF detection investigate rhythm irregularity or P-wave absence in the ECG, while deep learning approaches profit from the availability of annotated ECG databases to learn discriminatory features linked to different diagnosi
BACKGROUND: Sporadic primary hyperparathyroidism (pHPT) occurs separately and in several hereditary disorders including multiple endocrine neoplasia type 1. Irradiation to the neck, female gender, and age are well-identified risk factors that predispose to pHPT. The multiple endocrine neoplasia type 1 gene is the most commonly deranged gene in parathyroid adenomas and contains several polymorphism
Rapid advances in the development of sequencing technologies, numbers of commercial providers and diminishing costs have made DNA-based identification and diagnostics increasingly accessible to doctors and laboratories, eliminating the need for local investments in expensive technology and training or hiring of skilled technicians. However, reliable and comparable molecular analyses of bacteria in
BACKGROUND: The management of diverticular disease and its complications are an increasing burden to the health system. The natural history of conservatively managed diverticular abscesses (Hinchey I and II) is poorly described and it remains open to debate whether subsequent sigmoid resection is indicated after conservative management. This observational study compares outcomes of patients treate
Med äktenskapet följer en ekonomisk gemenskap mellan makar i form av giftorätt. När äktenskapet upphör, genom död eller skilsmässa, ska den ekonomiska gemenskapen makarna emellan upplösas. Avtalsfriheten mellan makar är omfattande. Äktenskapsbalkens bodelningsregler, där likadelning utgör en grundläggande princip, sätter annars en yttre ram. Denna uppsats syftar till att undersöka arvs- och bodelnWith marriage comes an economic community between spouses in the form of marital property. When the marriage ends, either through death or divorce, the economic community between the spouses should be dissolved. There is extensive freedom of contract between spouses. However, the rules of division of property in the Marriage Code, where equal division is a fundamental principle, provide an externa
Idrottsrörelsen är i dag Sveriges största folkrörelse och idrotten är världen över en angelägenhet för väldigt många människor. Idrottsrörelsen har en lång tradition av autonomi och självbestämmande, som tillsammans med en tilltagande kommersialisering har förstärkts av ett stort användande av skiljeavtal och egna skiljenämnder. Detta har gett upphov till frågan när allmänna domstolar egentligen bToday, the sports movement is the largest social movement in Sweden, and sports are a matter for many people all around the world. The Swedish sports movement has enjoyed a sense of autonomy and independence during a long period of time, and this order has been enhanced due to an increased extent of commercialisation, together with a vast use of arbitration agreements and own arbitration panels. T
PURPOSE: The "Shrunken pore syndrome" (SPS) is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatinC /eGFRcreatinine -ratio. Studies have demonstrated a high risk for cardiovascular morbidity and mortality for patients with SPS. In this discovery study, we explored associations between SPS and proteins implicated in cardiovascular dis
We compare abundance ratio trends in a sample of ∼11,000 Milky Way bulge stars (R GC < 3 kpc) from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) to those of APOGEE stars in the Galactic disk (5 kpc < R GC < 11 kpc). We divide each sample into low-Ia (high-[Mg/Fe]) and high-Ia (low-[Mg/Fe]) populations, and in each population, we examine the median trends of [X/Mg] versus [Mg/
Background: The purpose of this study is to investigate the impact of oxygen therapy on cardiovascular outcomes in relation to sex in patients with confirmed myocardial infarction (MI). Methods: The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction trial randomized 6,629 patients to oxygen at 6 L/min for 6-12 hours or ambient air. In the present subgroup analysis includi
Phosphorus induced eutrophication of freshwaters is one of the great global challenges. As the critical threshold concentration for eutrophication is very low, there is a strong need for development of phosphate sorbents with high affinity and selectivity. Single sheet iron oxide (SSI), a nanomaterial prepared from oxidation and exfoliation of layered iron(II)-iron(III) hydroxide (green rust), is
In a multicultural society, different cultures come in contact with each other which leads to many people need to relate to several cultures in their everyday lives. This study is aimed to highlight, analyze and discuss how young adult Malmö residents with a foreign background, reason about their identity creation in an environment where they are often reminded that they are different from the cro
In the last 30 years, a new mobile communications generation has been developed every 7 to 10 years. The last one that is currently under development is the Fifth Generation. This generation aims to fulfill a wide range of requirements for different use cases. To that end, a new radio access technology called New Radio (NR) has been developed. The main design principle behind NR is to allow enoug
Med SOU 2017:98 Tidiga förhör – nya bevisregler i brottmål föreslås en utökad möjlighet att använda dokumenterade förhör från förundersökningen som bevis i domstol. I uppsatsen berör jag den del av förslaget som innebär att utsagor som parter och vittnen lämnar i bevissyfte i större utsträckning ska dokumenteras med ljud och bild under förundersökningen och sedan presenteras i domstol. Detta innebWith SOU 2017:98 Early interrogations - new evidence rules in criminal cases an extended opportunity is given, to use documented interrogations from the preliminary investigation as evidence in court. In this essay I investigate the part of the bill concerning that statements left by parties, and witnesses for evidence purposes, should be documented using audio and video during preliminary investi
Makten att styra Sverige tillkommer statsråden, vilka utgör regeringen. Regeringsmakten begränsas genom lagbundenhet och funktionsfördelning. Riksdagens funktion är bland annat att kontrollera statsrådens arbete. Statsråden har ett såväl politiskt som rättsligt ansvar inför riksdagen. Uppsatsen utreder ifall regelverket för statsråds rättsliga ansvar för handlande i tjänsteutövningen är tillfredssThe power to govern Sweden belongs to the ministers, who form the government. The governmental powers are limited by law and by distribution of functions. One of the functions of the parliament is to monitor the work of the ministers. The ministers have both a political and a legal responsibility before the parliament. This essay examines whether the legal framework regarding the responsibility th
