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Substances in the food we eat stress the insulin-producing beta cells to death. Albert Salehi conducts research on how the beta cells function, and believes in new anti-diabetic drugs that can protect the beta cells and prevent type 2 diabetes. After studying pharmacology at Linköping University, Albert Salehi wanted to go on to study medicine. By chance he came into contact with Professor Ingemar
https://www.ludc.lu.se/beta-cells-diet-and-new-drugs - 2026-07-07
Background & Aims: RNA interference (RNAi) may offer new treatment options for chronic hepatitis B. Replicating via an RNA intermediate, hepatitis B virus (HBV) is known to be principally vulnerable to RNAi. However, beyond delivery, the relevant issues of potential off-target effects, target site conservation in circulating HBV strains, and efficacy of RNAi itself have not systematically been
Background Multiple myeloma cells uniformly overexpress CD38. We studied daratumumab, a CD38-targeting, human IgG1κ monoclonal antibody, in a phase 1-2 trial involving patients with relapsed myeloma or relapsed myeloma that was refractory to two or more prior lines of therapy. Methods In part 1, the dose-escalation phase, we administered daratumumab at doses of 0.005 to 24 mg per kilogram of body
A rapid and simple approach of lactose analysis is proposed based on 3rd generation amperometric biosensors employing cellobiose dehydrogenase (CDH) from Trametes villosa or Phanerochaete sordida immobilised on screen-printed carbon electrodes (SPCEs). After optimisation of the working conditions of the biosensors - pH of the carrier buffer, flow rate and applied potential - the sensors were able
Background/Aims: Our purpose was to investigate whether the new research criteria for Alzheimer's disease proposed in 2007 by Dubois et al. are valid in a naturalistic memory clinic sample. Method: Retrospective diagnostic analyses were carried out to compare the traditional diagnostic criteria for dementia with the new criteria suggested by Dubois et al. No patient had gone through all procedures
Professor Physical Geography with a specialisation in remote sensingContact details Email: lars [dot] eklundh [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageLars Eklundhs profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climat
https://www.nateko.lu.se/lars-eklundh - 2026-07-08
Researcher Contact details Email: anneli [dot] poska [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageAnneli Poskas profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Member of Strategic Research Area MERGE: ModElling the
https://www.nateko.lu.se/anneli-poska - 2026-07-08
Title: To make a living by library music; Opportunities and prerequisites. The purpose of this essay is to investigate how a music producer or composer can achieve placement of his or her music in commercials, TV-shows, computer games, and other media. What is required to make a living by composing and producing music today? This is a qualitative study made by interviewing six persons, who all in
Limited-slip differentials (LSD) are normally placed in high-end and race cars to improve the handling, by reducing the differential speed and balancing the torque between the driving wheels. However, electrical-activated LSD struggles to continuously eliminate the differential speed over extended periods of time. To overcome this, BorgWarner proposed a dual-functional clutch pack, featuring two d
In central Budapest, when the city of Pest was developing, urban policy led to small plots built on all four sides mak- ing up the larger neighborhood block structures. Each small lot was centered around its even smaller courtyard, lead- ing to a myriad of small open spaces with little sunlight or activity. Many of these plots today have fallen into disrepair, becoming parking lots or unused p
When initiating the research for my graduate paper I had a rather straightforward intent in mind. It was to determine if the research being conducted in the bio-health related field was negatively affected by the patent system. If the research was delayed by the patent system I wanted to apprehend why. I came to the conclusion that over the years the sphere where the exchange of intellectual prope
The splice variant INS-IGF2 entails the preproinsulin signal peptide, the insulin B-chain, eight amino acids of the C-peptide and 138 unique amino acids from an ORF in the IGF2 gene. The aim was to determine whether levels of specific INS-IGF2 autoantibodies (INS-IGF2A) were related to age at diagnosis, islet autoantibodies, HLA-DQ, or both, in newly diagnosed type 1 diabetes patients and controls
More scheduled outdoor stay is increasingly advocated for school children. This study measured 2(nd) , 5(th) and 8(th) graders' erythemal UV-exposure in September, March and May at four Swedish schools. We related those exposures, as fractions of total available ambient radiation, to the schools outdoor environments differing in amount of shade, vegetation, and peripheral city-scape quantified as
How does democracy affect income inequality? Most would expect democracy to reduce income inequality. There is a general consensus that indeed democratizations in Europe during the nineteenth and early twentieth century did decrease income inequality. More recent democratizations, those countries that democratized during the 1970s-1990s, however, do not seem to have had the same effect. The body o
Titel: När de som vet köper: Marknadens reaktion på insynshandel Seminariedatum: 2025-06-05 Kurs: FEKH89, Examensarbete i finansiering på kandidatnivå, 15 HP Författare: Marcus Brodin, Sebastian Dolk Persson, Carl Edlund Handledare: Maria Gårdängen Nyckelord: Insynshandel; Abnorm avkastning; Eventstudie; Befattningar; Transaktionsstorlek Forskningsfrågor: Hur reagerar marknaden på insynshanTitle: When Those Who Know Buy: The market’s reaction to insider trading Seminar date: 2025-06-05 Course: FEKH89, Bachelor Degree Project in Financial Management, Undergraduate Level, 15 ECTS-Credits Authors: Marcus Brodin, Sebastian Dolk Persson, Carl Edlund Advisor: Maria Gårdängen Key words: Insider trading; Abnormal return; Event study; Position; Transaction size Research questions: How
PURPOSE: Provision of adequate support is much needed to secure equal educational opportunities for students with developmental language disorder (DLD). Important perspectives on support provision and its impact on academic progress are held by school professionals, caregivers, and students with DLD. This study sought to further the current knowledge on the perceived relation between educational s
Background: Chimney endovascular aneurysm repair (chEVAR) techniques have been described to manage a group of patients who are unsuitable for either open aortic aneurysm surgery or a variety of standard endovascular repair techniques. The aim of this study was to assess the long-term clinical outcomes of chEVAR in emergency settings for patients with abdominal aortic aneurysms that have complex mo
The success of cell therapy for type 1 diabetes (T1D) depends on reliable differentiation of stem cells into functional pancreatic islets. Current protocols produce stem cell-derived islets (SC-islets) that contain non-endocrine cells and show limited maturity. We developed a robust protocol that generates functional SC-islets from all eight tested human pluripotent stem cell (hPSC) lines. Differe
Confidentiality in arbitration has for many years been taken for granted by the parties involved. The question has, until recently, almost never been debated. Even though there has been an assumption that there is a duty of confidentiality, it normally does not rest on a statutory basis. Two opposing views have been taken among judges and scholars regarding the legislative silence. One point of vi
