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Preeclampsia is a leading cause of pregnancy complications and affects 3-7% of pregnant women. This review summarizes the current knowledge of a new potential etiology of the disease, with a special focus on hemoglobin-induced oxidative stress. Furthermore, we also suggest hemoglobin as a potential target for therapy. Gene and protein profiling studies have shown increased expression and accumulat
Protein S is an anticoagulant protein that circulates in plasma in complex with C4b-binding protein; (C4BP) or in free form. Deficiency of protein S increases the risk of venous thrombosis. Measurement of free protein S, as compared to total levels, has been shown to be superior for prediction of protein S deficiency. We studied the effects of different handling protocols for an immuno- and a liga
The Commission’s decision to utilize FRAND as the Union’s premiere IPR licensing form in ICT standardization has sparked a debate among policy makers and stakeholders in the software industry regarding which licensing form is best suited for interoperability software standards in public procurement. Several voices from within the ICT industry as well as public authorities have openly supported the
The dynamic nature of human working memory, the general-purpose system for processing continuous input, while keeping no longer externally available information active in the background, is well captured in immediate free recall of supraspan word-lists. Free recall tasks produce several benchmark memory phenomena, like the U-shaped serial position curve, reflecting enhanced memory for early and la
Despite advancements world-over in access to basic education, hundreds of millions of children cannot read simple texts nor solve simple math problems, whether or not they have been to school. While there is evidence signalling the significant role of teachers in education outcomes, they are often seen as contributing to the learning crisis. The purpose of this thesis was to explore the perception
Research aim and questions: The aim of this research is to investigate the way Radio Free Europe’s Romanian Language Service presented the events of December 1989 in Romania. Since Radio Free Europe/Radio Liberty was one of the most important international broadcasting institutions during the Cold War, it is relevant to see what kind of interpretation was assigned to Romania’s 1989 political and
We give a method for designing a mechanical impedance to suppress the propagation of disturbances along a chain of masses. The key feature of our method is that it is scale free. This means that it can be used to give a single, fixed, design, with provable performance guarantees in mass chains of any length. We illustrate the approach by designing a bidirectional control law in a vehicle platoon i
The development of electronic states in krypton clusters is investigated by high-resolution core-level electron spectroscopy. The energy ordering of bulk versus surface 3d(-1)np(n > 5) core-excited states in neutral clusters is demonstrated to be reversed to the 3d(-1)5p level situation. The cluster 3d(-1)6p,7p states are proven to be at a lower energy than the corresponding atomic levels. These f
Free energy perturbations have been performed on two blue copper proteins, plastocyanin and nitrite reductase. By changing the copper coordination geometry, force constants, and charges, we have estimated the maximum energy with which the proteins may distort the copper coordination sphere. By comparing this energy with the quantum chemical energy cost for the same perturbation on the isolated cop
The mechanism of ascorbate oxidation was studied in rat liver microsomes. A continuous consumption of the added ascorbate was observed, which was accompanied with a prompt appearance of ascorbyl free radical and dehydroascorbate. Microsomes sustained steady-state level of ascorbyl free radical and dehydroascorbate till ascorbate was present in the medium. Ascorbyl free radical formation was dimini
This paper examines the Swedish record of competition in the supply of bank notes in the 19th century. Between 1831 and 1902, private commercial banks, organized as partnerships with unlimited liability for their owners, issued notes competing with the notes of the Riksbank, the bank owned by the Riksdag, the Swedish parliament. The private banks turned out to be competitive in this market despite
Based on national legislations, Swedish municipal authorities have the responsibility as well as the means to shape their own transport and energy systems and lead the transformation towards fossil fuel free cities. In this report we explore how sixteen Swedish municipalities work toward fossil fuel free visions and goals with a particular emphasis on the urban transport and energy systems. We der
Background: Previous studies have reported an increased fracture risk after bariatric surgery. Objective: To investigate the association between different bariatric surgery procedures and fracture risk. Methods: Incidence rates and hazard ratios for fracture events were analysed in the Swedish Obese Subjects study; an ongoing, nonrandomized, prospective, controlled intervention study. Hazard ratio
Health economic evaluations provide decision makers with information whether the health effects of one intervention come at a reasonable cost in relation to a comparator. The existing evidence indicate that health promotion for community-dwelling older people result in a range of positive health outcomes, but there is a general lack of health economic evaluation. The aim was to evaluate cost-effec
