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Smart microscopy lies at the intersection of biology, optics, engineering, and computer science. Unlike traditional microscopes, smart systems actively adapt their acquisition settings in real time based on information extracted from the sample, allowing experiments to navigate competing demands such as resolution, speed and sample health. In this review, we present a practical framework for what
Bacteriophages must overcome diverse bacterial immune systems, yet the molecular principles enabling such escape remain poorly understood. Here, we show that the phage homing endonuclease SegB facilitates immune evasion by promoting the segmental amplification of anti-defense loci. The antiphage defense Septu inhibits phage T6 replication by cleaving the variable loop of tRNATyr. We show that SegB
Immersive visual environment can deceive our interoceptive perception of how we move relative to our environment. If the visual environment or a high reliance on vision produces straining work conditions, motion sickness or is associated with a medical disorder, the causes merit addressing. Therefore, the purpose of this study was to investigate whether postural control adapts to challenging visua
The oxygen reduction reaction (ORR) on platinum is limited by a substantial overpotential, which hampers the efficiency of fuel cell technologies. While adsorbate binding energies have been widely used to explain ORR kinetics, we here illustrate a more complex role of platinum surface oxides, which are often ambiguously defined in the literature. We use operando total reflection X-ray absorption f
Under electrochemical polarization, many electrocatalysts can undergo oxidation that alters their reactivity and can lead to restructuring and dissolution. In this context, the structure-property relationships of electrocatalysts, as well as their kinetics and dynamic behaviour, are still poorly understood. This knowledge gap mainly relies on the limitations of many traditional spectroscopic and s
Traumatic brain injury and stroke often result in contralateral sensorimotor deficits, including asymmetric posture. While these lateralized effects are classically attributed to neural tract disruption, recent evidence supports the existence of a complementary humoral pathway. Our previous work demonstrated that the neurohormone Arg-vasopressin (AVP) mediates right hindlimb responses to left-side
The dissociation of NO is a critical step in its catalytic reduction to N2, which is key to automotive exhaust treatment. Here, we examine the role of Rh atomic steps in the NO dissociation reaction under 0.05 mbar NO. We use a Rh crystal sample curved around the (111) direction and ambient-pressure X-ray photoelectron spectroscopy to probe different Rh surfaces subject to the very same reaction c
The interest in putting a price on carbon emissions is increasing in pace with the urgency of climate change. In this article we compare the adoption of one such policy instrument, carbon taxation, in the cases of Sweden and Mexico. We use a theoretical framework that focuses on economic and environmental factors influencing the policy process via distinct policy areas, as well as the mechanisms t
Nanoplastics are increasingly being recognized as a global pollutant. However, relatively few studies report directly measured concentrations of nano- and microplastics in environmental samples, although available data suggest levels of up to 0.5 mg L−1 in lake water, which is surprisingly high. Their degradation in the environment, particularly under UV irradiation, is still poorly understood. He
We must recognize that plastics likely constitute a pervasive background in many environments. Beyond their previously documented risks to ecosystems and human health, plastics may also exert unintended influences on laboratory experiments, potentially distorting experimental outcomes. Here, we demonstrate that ultrasound treatment of commonly used laboratory test tubes releases nanoplastics into
Attosecond pulses produced by high-order harmonic generation in gases driven by intense laser fields have become a cornerstone technique for probing ultrafast electronic motion in matter. These applications require a good knowledge of the temporal and spectral properties of the emitted radiation. In this work, we generate a train of two to three attosecond pulses that we characterize using two-col
Photoionization of atoms by high-order harmonics in the presence of a laser may lead to quantum interference from which information about the photoionization dynamics or the light fields can be extracted. Traditionally, this interference arises from two-photon transitions involving the absorption of consecutive harmonics combined with the absorption and stimulated emission of a laser photon. In th
Accurate three-dimensional (3D) tracking of dynamic particles in highly scattering, reacting environments like metal combustion remains challenging for conventional particle tracking velocimetry (PTV). While digital holography enables volumetric imaging, traditional holographic PTV suffers from significant depth positioning errors and velocity fluctuations due to inefficient frame-by-frame process
The aim of this thesis was to analyze and compare the effects of various types of speed-reducing measures (speed humps, raised pedestrian and cycle crossings, dynamic speed bumps, and combined solutions) on vehicle speeds and traffic safety on selected streets in Helsingborg, Sweden. The study focused on residential streets, school zones, and main roads with different traffic environments. The met
This study investigates the effect of remediation of contaminated sites on nearby property prices in Västra Götaland, Sweden. Using a hedonic property framework combined with a multi-period Difference-in-Differences method, the aim is to examine whether remediation leads to measurable changes in housing values. The analysis builds on the approach used by Haninger, Ma, and Timmins (2017), but appli
Bioenergy is perceived to play a vital role in climate mitigation, transition to renewable energy consumption, energy security, and local and rural socio-economic development. However, exploiting renewable bioenergy resources may need to be more sustainable in the current predominant paradigm. In this study, we raise two broad research questions: (1) what are the significant challenges to the curr
AbstractBackgroundThe increasing prevalence of obesity has led to a rise in bariatric surgery as an effective intervention for weight loss and associated co-morbidities. However, concerns persist regarding increased alcohol consumption after surgery.ObjectivesTo objectively assess long-term changes in alcohol use after bariatric surgery, we used the highly specific alcohol biomarker phosphatidylet
Drug use disorder (DUD) is distributed unevenly over geographical areas of Sweden. We explore, using geographically weighted regression, the proportion of this variation associated with community levels of genetic risk, social deprivation and urbanicity. In the 5983 Demographic Statistical areas (DeSOs) within Sweden, we predict DeSO prevalence from mean genetic risk for DUD, measured by the famil
