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We give a complete proof of the classical Benjamin and Lighthill conjecture for arbitrary two-dimensional steady water waves with vorticity. We show that the flow force constant of an arbitrary smooth solution is bounded by the flow force constants for the corresponding conjugate laminar flows. We prove these inequalities without any assumptions on the geometry of the surface profile and put no re
Background: Chronic lung disease (CLD) occurs frequently in preterm infants and is associated with respiratory morbidity. Bronchodilators have the potential effect of dilating small airways with muscle hypertrophy. Increased compliance and tidal volume, and decreased airway resistance, have been documented with the use of bronchodilators in infants with CLD. Therefore, bronchodilators are widely c
In this article, the account-making of social workers and institutional care staff on locked institutional care for youth is analysed, based on empirical material consisting of 10 interviews with 25 members of the two professions. The study departs from a Swedish context where locked institutional care for youth is mainly provided for individuals who are in compulsory care due to criminality, drug
Heart failure (HF) is a leading cause of death and disability globally. HF represents the common end- stage of most heart conditions, during which the heart is unable to generate sufficient output of blood for the metabolic demands of the body and intracardiac pressures increase. Different heart diseases display specific molecular pathophysiologies, but common pathways are also present that drive
We contribute to the argument for a “new” business history employing a quantitative approach. We illustrate opportunities for new perspectives from this approach using a novel microlevel longitudinal database comprising 131 variables for 1,419 cooperative creameries in Denmark for the period 1898–1945, which we also document and make available to the scholarly community. We present a number of app
During the last decade, the application of strontium isotope analysis (87Sr/86Sr) has increased rapidly. The understanding of the strontium isoscape and the construction of a strontium isotope baseline in southern Scandinavia are biased toward Denmark and southwestern to eastern Scania. We report the results of new baseline samples in Halland and the Bjäre Peninsula, adding to the rich strontium i
A search for the associated production of a heavy resonance with a top-quark or a top-antitop-quark pair, and decaying into a tt¯ pair is presented. The search uses the data recorded by the ATLAS detector in pp collisions at s=13 TeV at the Large Hadron Collider during the years 2015–2018, corresponding to an integrated luminosity of 139 fb-1. Events containing exactly one electron or muon are sel
Introduction: Opinions differ on what drugs have both a rationale and a development potential for the treatment of bladder storage dysfunction. Areas covered: In the present review, the focus is given to small molecule blockers of TRP channels (TRPV1, TRPV4, TRPA1, and TRPM8), P2 × 3receptor antagonists, drugs against oxidative stress, antifibrosis agents, cyclic nucleotide–dependent pathways, and
PURPOSE: To follow the clinical outcome after surgery for cervical radiculopathy caused by degenerative cervical disc disease and to compare it with the outcome after conservative treatment.METHOD: Forty-three patients all awaiting surgery were studied prospectively. A control group of 39 conservatively treated patients were chosen, matched for gender and age. All patients rated their Sickness Imp
In Latin-America -as in most parts of the world- indigenous peoples are ‘the poorest of the poor, and the most excluded of the excluded’. Poverty goes hand in hand with their situation of vulnerability, exclusion and disempowerment. How can this situation be changed? How to find adequate frameworks able to facilitate the overturn of their structural disenfranchisement? Departing from the jurisprud
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of higher versus standard doses of caffeine on mortality and major neurodevelopmental disability in preterm infants with (or at risk of) apnea, and preterm infants peri-extubation. To determine the effects of early versus late discontinuation of caffeine administration on m
Background: The 2017 Alzheimer’s disease (AD) Strategic Biomarker Roadmap (SBR) structured the validation of AD diagnostic biomarkers into 5 phases, systematically assessing analytical validity (Phases 1–2), clinical validity (Phases 3–4), and clinical utility (Phase 5) through primary and secondary Aims. This framework allows to map knowledge gaps and research priorities, accelerating the route t
Background: To reduce local recurrence risk, rectal washout (RW) is integrated in the total mesorectal excision (TME) technique when performing anterior resection (AR) for rectal cancer. Although RW is considered a safe practice, data on the complication risk are scarce. Our aim was to examine the association between RW and 30-day postoperative complications after AR for rectal cancer. Methods: Pa
Pepsin-like aspartic proteases (PAPs) are a class of aspartic proteases which shares tremendous structural similarity with human pepsin. One of the key structural features of PAPs is the presence of a β-hairpin motif otherwise known as flap. The biological function of the PAPs is highly dependent on the conformational dynamics of the flap region. In apo PAPs, the conformational dynamics of the fla
One can falsely assume that it is well known that bacteremia is associated with higher mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture-negative and culture-positive sepsis with different conclusions depending on study design. The aim of this study was to describe outcome for critically ill patients with either culture-positive or -negative sepsis in a
We analyze the problem of allocating indivisible objects and monetary compensations to a set of agents. In particular, we consider envy-free and budget-balanced rules that are least manipulable with respect to agents counting or with respect to utility gains. A key observation is that, for any profile of quasi-linear preferences, the outcome of any such least manipulable envy-free rule can be obta
Städer, och framför allt stadsdelar, är nyckelplatser för att tillhandahålla en uppbyggd miljö med direkta kopplingar till sociala och miljömässiga frågor. De ses i allt högre grad som platser för strategiska åtgärder i en omställning till hållbarhet och resiliens, med stora möjligheter till grundläggande samhällsförändringar. Inramningen (så kallad framing) på stadsdelsnivå av problem och lösning
