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Pre-fractionation of a complex mixture of proteins increases the resolution in analytical separations of proteins from cells, tissues or organisms. Here we demonstrate a novel method for pre-fractionation of membrane proteins by a detergent-based aqueous two-phase system. Membrane proteins are strongly under-represented in proteomic studies based on two-dimensional electrophoresis (2-DE). As a mod
The secosteroid hormone active vitamin D [1,25(OH)(2)D-3] is a key player in the regulation of calcium homeostasis and bone mineralization. In addition, it has antiproliferative and prodifferentiating effects on various cells in vitro and in vivo. The action of 1,25(OH)(2)D-3 is mediated through the vitamin D receptor (VDR), which belongs to the superfamily of steroid/thyroid hormone nuclear recep
Popular Abstract in Swedish Bakgrund För att diagnostisera förändringar i käkbenet är röntgenundersökning av stor betydelse. En bendestruktion blir synlig i röntgenbilden först när relativt stor mängd ben försvunnit. Flera tidigare studier har visat att destruktionen inte ses förrän den påverkar den kompakta yttre delen av käkbenet. Andra studier har däremot visat att destruktionen kan ses tidigaThe aim was to study digital radiography and to evaluate the influence of image processing on digital dental radiographs for the assessment of periapical lesions. In four studies, artificial bone lesions were made periapically and interradicularly in the mandibular premolar and molar regions. In a clinical study, direct digital radiographic images depicting the periapical bone tissue of different
Popular Abstract in Swedish Data från AVHRR-sensorn ombord på NOAA satelliten används operationellt för att övervaka vegetation och torka i global och regional skala. Ett vegetationsindex (NDVI) används som en indikator på grön växtbiomassa. Analys av AVHRR NDVI-data över Östafrika pekar på att det finns ett starkt samband mellan den ytmässiga fördelingen av vegetation och NDVI i arida och semi-aIn this thesis, an assessment is made of the performance of the Normalized Difference Vegetation Index (NDVI) derived from coarse resolution data from the NOAA AVHRR sensor, with particular reference to mapping and monitoring of drought and vegetation in East African vegetation and climatic conditions. Methods for analysing time series of satellite data are investigated. By studying the empirical
Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which the 0 cells in the pancreas are destroyed by the body's own immune system. IL12 plays a role in pathological situations, such as septic shock, tissue damage during inflammation, and organ-specific autoimmune diseases. In NOD mice, administration of IL12 induces T1DM and administration of IL12 antagonists prevents T1DM. Linkage and a
Given electronic wave functions generated by the MCHF_CI program (LSJ format), this program calculates diagonal Lande a factors that determine separations of magnetic sublevels in weak external magnetic fields. In addition the program computes off-diagonal Lande factors and constructs the total interaction matrix for an atom in a magnetic field. By diagonalizing the interaction matrix and plotting
A new coated time-domain reflectometry (TDR) probe design is described and evaluated. In contrast to previous coated TDR probes, our probe may be used to measure both the dielectric constant (K-a) and bulk electrical conductivity (sigma(a)) in saline porous media. This was made possible by attaching two coaxial cables to a 0.27-m three-rod with a coated central rod. The shield of the first cable w
Effects of ultraviolet (UV)-B radiation and acidification on pelagic carbon flux in a humic lake (dissolved organic carbon [DOC] similar to15 mg C L-1) were studied in a mesocosm experiment during the summer of 2000. Triplicate tanks (107 liters volume, 1 m high) were exposed to natural solar radiation, a daily extra dose of UV-B radiation, or kept dark. One set of tanks was submitted to a decreas
A comparison, based on a study of how time is treated, between three development tools for real time expert system is exposed. After a presentation of the tools, some of their advantages and disadvantages arepinpointed. Since these tools are only a partial answer to the problem of real time within the expert system's area, a standpoint concerning a good use of each tool is given.
Two methods for visual evaluation of image quality of clinical radiographs have been compared. In visual grading analysis (VGA) specified anatomical structures in an image are visually compared with the same structures in a reference image, and in a free-response forced error (FFE) experiment - an extension of conventional ROC (receiver operating characteristics) analysis - the objective is to cor
1. Five oligotrophic clear-water lakes on the Faroe Islands were studied during August 2000. Algal and bacterial production rates, community respiration, and CO2 saturation were determined. In addition, we examined the plankton community composition (phytoplankton and heterotrophic nanoflagellates) and measured the grazing pressure exerted by common mixotrophic species on bacteria. 2. High respir
Ultrafast accelerator-based sources combined with synchronized femtosecond lasers are currently being developed. The method described here is intended as a jitter monitor at such facilities. We report on the possibility of extracting a time-offset signal between two different synchronized ultrashort light pulses. The method is based on sum-frequency generation in a nonlinear crystal. Aiming at ext
This article suggests an extension of the standard decomposition of the concentration index that allows for an exploration of the pathways through which socioeconomic background relates to income-related health inequality. This novel approach is contrasted to the standard one using a panel of Swedish women in Statistics Sweden’s Survey of Living Conditions for one vital health-related behavior, sm
