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Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it is not fully understood how and when the onset of circulation affects HSC emergence. Here we show that in Ncx1−/− mouse embryos devoid of circulation the HSC l
There is a great need to find cheaper but still efficient treatment methods for wastewater. This study aimed to test the purifying performance of three different Moringa oleifera varieties that were cultivated in Tunisia on raw (RUW) and secondary treated urban wastewater (TUW). The seeds of the Mornag, Egyptian, and Indian varieties were powdered, added to the water (at concentrations of 0, 50, 1
A mathematical framework and accompanying numerical algorithm exploiting the continuity equation for 4D reconstruction of spatiotemporal attenuation fields from multi-angle full-field transmission measurements is presented. The algorithm is geared towards rotation-free dynamic multi-beam X-ray tomography measurements, for which angular information is sparse but the temporal information is rich. 3D
Background. School health programs need to target all aspects of physical, psychological, and social well-being. Using a slightly modified version of the COSMIN Risk of Bias checklist, we developed and conducted the first validation of the School Health Assessment Tool for Primary Schools (SHAT-PS). Method. The exploratory sequential mixed method was used in this study. In the first phase, scienti
The purpose of this perspective article is to critically explore the launch of the mission for 100 climate neutral cities in Europe. An overview of the mission approach in general is first presented, where key aspects and emerging critiques are identified. Second, key elements of the mission for 100 climate neutral cities in Europe are introduced along with some of its challenges and ambiguities.
Editor's notes: This article discusses self-awareness in wearable edge devices to enable real-time and long-term health monitoring. The authors use the notion of self-awareness to improve the battery life of edge wearable sensors for multimodal health and workload monitoring. This approach leads to a 27.6% lower energy consumption with less than 6% of performance loss. - Umit Y. Ogras, Arizona Sta
Continuous monitoring of patients suffering from cardiovascular diseases and, in particular, myocardial infarction (MI) places a considerable burden on health-care systems and government budgets. The rise of wearable devices alleviates this burden, allowing for long-term patient monitoring in ambulatory settings. One of the major challenges in this area is to design ultra-low energy wearable devic
Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the
Due to chemical agents consumption and energy demand during traditional Cr(VI)-containing wastewater treatments, it is essential to explore a cost-effective and sustainable technique to remove Cr(VI) from wastewater. Combining of phytoremediation and bio-electrochemical technology, an Acorus calamus L. constructed wetland-microbial fuel cell (CW-MFC) was ingeniously designed to purify Cr(VI)-conta
Musculoskeletal tissues are complex hierarchical materials where mechanical response is linked to structural and material properties at different dimensional levels. Therefore, high-resolution three-dimensional tomography is very useful for assessing tissue properties at different scales. In particular, Synchrotron Radiation micro-Computed Tomography (SR-microCT) has been used in several applicati
Dynamic resource management is a difficult problem in modern microservice applications. Many proposed methods rely on the availability of an analytical performance model, often based on queueing theory. Such models can always be hand-crafted, but this takes time and requires expert knowledge. Various methods have been proposed that can automatically extract models from logs or tracing data. Howeve
Bone is a composite material where tubular osteon structures surrounded by thin interfaces reinforce the tissue at the microscale. These interfaces provide alternative weak paths for crack growth and give rise to potent extrinsic toughening mechanisms. Numerical models can help to gain a deeper understanding of fracture resistance in bone, however, capturing the interface mechanics is key. For thi
The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples fr
Collaborative robots have been designed to perform tasks where human cooperation may occur. Additionally, undesired collisions can happen in the robot’s environment. A contact classifier may be needed if robot trajectory recalculation is to be activated depending on the source of robot–environment contact. For this reason, we have evaluated a fast contact detection and classification method and we
Im März 1847 erließ Papst Pius IX die Enzyklika „Praedecessores Nostros“, die die katholische Geistlichkeit weltweit aufrief, zur Linderung der großen irischen Hungersnot drei Tage der Gebete und Kollekten abzuhalten. Die Bischöfe, die diese Botschaft in den italienischen Staaten weiterführten, verfassten ihrerseits Appelle zur lokalen Durchführung des Triduums. Sie animierten die Gläubigen, dem B
